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AP 14145 hydrochloride

AP 14145 hydrochloride Structure
AP 14145 hydrochloride structure
CAS No.
2387505-59-9
Chemical Name:
AP 14145 hydrochloride
Synonyms
AP 14145 hydrochloride
CBNumber:
CB08202895
Molecular Formula:
C18H18ClF3N4O
Molecular Weight:
398.81
MDL Number:
MOL File:
2387505-59-9.mol
Last updated:2023-06-30 15:45:59
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AP 14145 hydrochloride Properties

solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol

AP 14145 hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 6481 AP14145hydrochloride ≥98%(HPLC) 2387505-59-9 5 $249 2021-12-16 Buy
Product number Packaging Price Buy
6481 5 $249 Buy

AP 14145 hydrochloride Chemical Properties,Uses,Production

Biological Activity

AP 14145 hydrochloride is a KCa2 (small conductance Ca2+-activated potassium) channel negative allosteric modulator (IC50 = 1.1 μM). Increases the EC50 of Ca2+ on KCa2.3 channels by ~3-fold. Prolongs atrial effective refractory period (AERP) in rats. Reduces atrial fibrillation (AF) duration and prolongs atrial refractoriness without affecting ventricular refractory period in an animal AF model.

storage

Store at -20°C

AP 14145 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

AP 14145 hydrochloride Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
AP 14145 hydrochloride 2387505-59-9