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2S,4R-Sacubitril

2S,4R-Sacubitril Structure
2S,4R-Sacubitril structure
CAS No.
2307668-79-5
Chemical Name:
2S,4R-Sacubitril
Synonyms
[1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxobutyl)amino]-α-methyl-, 4-ethyl ester, (αR,γS)-rel-
CBNumber:
CB09272710
Molecular Formula:
C25H31NO5
Molecular Weight:
425.53
MDL Number:
MOL File:
2307668-79-5.mol
Last updated:2024-07-02 08:54:58
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2S,4R-Sacubitril Properties

Boiling point 658.5±55.0 °C(Predicted)
Density 1.136±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 4.76±0.10(Predicted)
form Oil
color Colorless to light yellow

2S,4R-Sacubitril price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
A2B BA33135 2S,4R-Sacubitril 99% 2307668-79-5 1mg $685 2021-12-16 Buy
A2B BA33135 2S,4R-Sacubitril 99% 2307668-79-5 5mg $2035 2021-12-16 Buy
Product number Packaging Price Buy
BA33135 1mg $685 Buy
BA33135 5mg $2035 Buy

2S,4R-Sacubitril Chemical Properties,Uses,Production

Description

2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and Drug Administration for use in combination with valsartan for the treatment of patients with heart failure.

References

[1]. Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.

2S,4R-Sacubitril Preparation Products And Raw materials

Raw materials

Preparation Products

2S,4R-Sacubitril Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 Gsiyu@solarbio.com China 50471 58
Supplier Advantage
Beijing Jin Ming Biotechnology Co., Ltd. 58
Beijing Solarbio Science & Tecnology Co., Ltd. 58

2307668-79-5(2S,4R-Sacubitril)Related Search:

LCZ696(valsartan + sacubitril) impurity 35 [1,1′-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, 4-methyl ester, calcium salt (2:1), (αR,γS)- LCZ696(valsartan + sacubitril) impurity 31 [1,1'-Biphenyl]-4-pentanoic acid, γ-(acetylamino)-α-methyl-, (αR,γS)- LCZ696(valsartan + sacubitril) impurity 34
Sacubatrava valsartan sodium hydrate Sacubitril Impurity 43 Sacubitril Sodium Sacubitril Methyl esterQ: What is Sacubitril Methyl ester Q: What is the CAS Number of Sacubitril Methyl ester Sacubitrilat-d5

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[1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxobutyl)amino]-α-methyl-, 4-ethyl ester, (αR,γS)-rel- 2307668-79-5