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Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]-

Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]- structure

CAS No.: 1225177-95-6

Chemical Name:: Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]-

Synonyms: Covidcil-19;Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]-

CBNumber:: CB09785926

Molecular Formula:: C16H14N4O2

Molecular Weight:: 294.31

MDL Number:

MOL File:: 1225177-95-6.mol

Last updated:2023-06-30 15:45:59

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Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]- Properties

Boiling point	580.2±60.0 °C(Predicted)
Density	1.414±0.06 g/cm3(Predicted)
solubility	To be determined:2.94(Max Conc. mg/mL);10.0(Max Conc. mM)
pka	3.88±0.10(Predicted)

Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]- Chemical Properties,Uses,Production

Description

Covidcil-19 binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with high affinity (Kd = 11 nM). It stabilizes the hairpin's folded state and reduces frameshifting efficiency in cells. Covidcil-19 inhibits viral propagation and reduces viral infectivity by > 3.5 orders of magnitude.

Uses

3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic Acid is used in the preparation of some molecular binders that targets the SARS-CoV-2 RNA genome, the causative agent of COVID-??19.

storage

Store at -20°C

Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]- Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28091	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

Benzoic acid, 3-[[4-(methylamino)-2-quinazolinyl]amino]- Covidcil-19 1225177-95-6