ChemicalBook >> CAS DataBase List >>3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-methyl-1,4-dithiin-2-yl)-, 3,5-bis(4-pyridinylmethyl) ester

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-methyl-1,4-dithiin-2-yl)-, 3,5-bis(4-pyridinylmethyl) ester

CAS No.
1000817-20-8
Chemical Name:
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-methyl-1,4-dithiin-2-yl)-, 3,5-bis(4-pyridinylmethyl) ester
Synonyms
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-methyl-1,4-dithiin-2-yl)-, 3,5-bis(4-pyridinylmethyl) ester
CBNumber:
CB110059314
Molecular Formula:
C26H25N3O4S2
Molecular Weight:
507.62
MDL Number:
MOL File:
1000817-20-8.mol
Last updated:2023-03-31 09:12:58

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-methyl-1,4-dithiin-2-yl)-, 3,5-bis(4-pyridinylmethyl) ester Properties

Boiling point 671.1±55.0 °C(Predicted)
Density 1.316±0.06 g/cm3(Predicted)
pka 4.91±0.10(Predicted)

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-methyl-1,4-dithiin-2-yl)-, 3,5-bis(4-pyridinylmethyl) ester Chemical Properties,Uses,Production

Description

NIK-250 is a P-glycoprotein inhibitor. NIK250 might be useful in reversing MDR, which often develops during chemotherapy of advanced or hormone-resistant prostatic cancer. NIK250 could also reverse multidrug resistance in human glioma cells. The glioma cell lines were the two MRP-expressing cell lines, T98G and IN500, an MDR1-expressing cell line, CCF-STTG1, and the MRP1 MDR1-non-expressing cell line, IN157.

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-methyl-1,4-dithiin-2-yl)-, 3,5-bis(4-pyridinylmethyl) ester Preparation Products And Raw materials

Raw materials

Preparation Products

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-methyl-1,4-dithiin-2-yl)-, 3,5-bis(4-pyridinylmethyl) ester Suppliers

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TargetMol Chemicals Inc.
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TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24016 58
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-methyl-1,4-dithiin-2-yl)-, 3,5-bis(4-pyridinylmethyl) ester 1000817-20-8