GHRP-2 | 158861-67-7

GHRP-2 Properties

Melting point	149 - 151°C
Boiling point	1265.3±65.0 °C(Predicted)
Density	1.270±0.06 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO (Slightly, Sonicated), Water (Slightly)
pka	13.40±0.46(Predicted)
form	lyophilized powder
color	white to beige
Stability	Hygroscopic
InChIKey	HRNLPPBUBKMZMT-RDRUQFPZSA-N
SMILES	C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC1=CC=C2C(=C1)C=CC=C2)NC(=O)[C@@H](C)N
CAS DataBase Reference	158861-67-7(CAS DataBase Reference)
FDA UNII	E6S6E1F19M

SAFETY

Risk and Safety Statements

WGK Germany	3

GHRP-2 price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML2056	Pralmorelin trifluoroacetate salt ≥97% (HPLC)	158861-67-7	1MG	$162	2023-01-07	Buy
Sigma-Aldrich	SML2056	Pralmorelin trifluoroacetate salt ≥97% (HPLC)	158861-67-7	5MG	$650	2023-01-07	Buy
Alfa Aesar	J66029	Growth Hormone Releasing Peptide-2	158861-67-7	25mg	$270	2021-12-16	Buy
Alfa Aesar	J66029	Growth Hormone Releasing Peptide-2	158861-67-7	5mg	$113	2021-12-16	Buy
Usbiological	382743	eIF3A	158861-67-7	96Tests	$729	2021-12-16	Buy

Product number	Packaging	Price	Buy
SML2056	1MG	$162	Buy
SML2056	5MG	$650	Buy
J66029	25mg	$270	Buy
J66029	5mg	$113	Buy
382743	96Tests	$729	Buy

GHRP-2 Chemical Properties,Uses,Production

Description

Pralmorelin (also known as KP-102, GPA-748, GHRP-2, and Growth Hormone Releasing Peptide-2) is a potent GH secretagogue in development as a diagnostic agent for growth hormone deficiency and for the treatment of pituitary disorders and GH deficiency. It acts as signal molecules that are involved in the control of cell growth and differentiation.

Uses

Growth hormone releasing factor. Pralmorelin is a growth hormone secretagogue that acts on the pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone release.

Definition

ChEBI: Pralmorelin is an oligopeptide.

benefits

Regulation of blood pressure, increased strength and healing, reduced injury, increased cell rejuvenation, increase in lean muscle mass and stronger bones.

Biochem/physiol Actions

Pralmorelin, also known as Growth hormone-releasing peptide 2 or GHRP-2, is an orally-active, synthetic peptide analogue of met-enkephalin that acts as a ghrelin/growth hormone secretagogue receptor (GHSR) agonist to selectively stimulate the ghrelin receptor and cause growth hormone release. Pralmorelin (GHRP-2) has been used clinically for the assessment of growth hormone deficiency (GHD), It has also been shown to have anti-inflammatory activity.

Mechanism of action

GHRP-2 is an agonist of ghrelin, a gut peptide and also known as “the hunger hormone”, which binds to the growth hormone secretagogue receptor. Pralmorelin works to enhance natural growth hormone production in two ways. First, the GHRP-2 intensifies the natural growth hormone releasing signal, resulting in a substantial secretion of growth hormone. Second, it suppresses a hormone in the body called somatostatin, also known as growth hormone inhibiting hormone (GHIH). Somatostatin generates the body to decrease its natural growth hormone production. By restricting the activity of somatostatin, GHRP-2 can improve growth hormone creation, resulting in increased natural growth hormone levels. GHRP-2 also activates ghrelin, a peptide hormone produced in the gastrointestinal system, which has strong effects on growth hormone production and appetite.

Side effects

No side effects or toxicities were observed. Thus, GHRP-2 is well tolerated and can stimulate GH secretion. Formulations or routes of administration that allow for a longer duration of action will likely be needed to use GHRP-2 in therapy[1].

References

[1] V Mericq. “Effects of eight months treatment with graded doses of a growth hormone (GH)-releasing peptide in GH-deficient children.” Journal of Clinical Endocrinology & Metabolism 83 7 (1998): 2355–60.

GHRP-2 Preparation Products And Raw materials

Raw materials

Preparation Products

GHRP-2 Suppliers

Global( 280)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	970	58
Zhuzhou New Peptides Tech Co.,Ltd.	+86-18073326374 +86-18073326374	sales@goodpeptides.com	China	56	58
Strong peptide cross-border e-commerce Co. LTD	+undefined13930052870	qt01@qiangtaipharm.com	China	84	58
Qingdao Xinli Technology Development Co., Ltd.	+8616632313095	xinlikeji01@qdxlchem.com	China	134	58
Sea Biological Co.,LTD	+86-13865152372 +86-13865152372	tim@sea-biol.com	China	71	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3512	58
Shanghai Affida new material science and technology center	+undefined15081010295	admin@oudaxin.com	China	114	58
Huaian Banting Trading Co., Ltd.	+86-13102576090	sales5@bantingpeptide.com	China	35	58
Shanghai Longyu Biotechnology Co., Ltd.	+8619521488211	info@longyupharma.com	China	2529	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12840	58

Supplier	Advantage
hebei hongtan Biotechnology Co., Ltd	58
Zhuzhou New Peptides Tech Co.,Ltd.	58
Strong peptide cross-border e-commerce Co. LTD	58
Qingdao Xinli Technology Development Co., Ltd.	58
Sea Biological Co.,LTD	58
Hebei Miaoyin Technology Co.,Ltd	58
Shanghai Affida new material science and technology center	58
Huaian Banting Trading Co., Ltd.	58
Shanghai Longyu Biotechnology Co., Ltd.	58
Hebei Mojin Biotechnology Co., Ltd	58

View Lastest Price from GHRP-2 manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-22	GHRP-2 Acetate 158861-67-7	US $40.00 / box	1box	99%	5000boxes	Hebei Zhuanglai Chemical Trading Co.,Ltd
2024-11-22	GHRP-2 Acetate 158861-67-7	US $0.00 / G	1G	99%	20kg	CONTIDE BIOTECH CO.,LTD
2024-11-22	GHRP-2 158861-67-7	US $30.00-20.00 / box	1box	99.9%	500 box	hebei hongtan Biotechnology Co., Ltd

GHRP-2 Acetate
158861-67-7
US $40.00 / box
99%
Hebei Zhuanglai Chemical Trading Co.,Ltd

GHRP-2 Acetate
158861-67-7
US $0.00 / G
99%
CONTIDE BIOTECH CO.,LTD

GHRP-2
158861-67-7
US $30.00-20.00 / box
99.9%
hebei hongtan Biotechnology Co., Ltd

GHRP-2 Spectrum

Pralmorelin(158861-67-7)¹HNMR

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D-ALANYL-3-(2-NAPHTHALENYL)-D-ALANYL-L-ALANYL-L-TRYPTOPHYL-D-PHENYLALANYL-L-LYSINAMIDE ACETATE ADDUCT GHRP-2 (FREE PEPTIDE) (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-naphthalen-2-yl-propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]-N-[(2R)-2-aminopropanoyl]hexanamide D-Ala-bata-(2-naphthyl)-D-Ala-Trp-D-Phe-Lys amide D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide D-Ala-D-β-Nal-Ala-Trp-D-Phe-Lys-NH2 4-dichloro-1 8-naphthyridine 3-d]pyriMidine TFA 2-trifluoroethyl)thiazole 5-(Tributylstannyl)-2-(2 3-a]pyrazine-3 4]triazolo[4 6-dihydro-[1 7-tert-butyl 3-ethyl 5 7-naphthyridine-3 7-tert-butyl 3-Methyl 5 4]triazine-6-carboxylate ethyl 4-chloropyrrolo[1 tert-butyl 3-Methoxy-5 2-trifluoroethyl)cyclopropyl)stannane Tributyl(2-(2 Growth HorMone Releasing Hexapeptide-2 Monoclonal Anti-MAP Kinase, Activated (Diphosphorylated ERK-1& GH secretagogue receptor GH-releasing peptide receptor GHS receptor Acetic acid ghrelin -2 L-Lysinamide, D-alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl- PRALMORELIN D-ALA-D-NAL(2)-ALA-TRP-D-PHE-LYS-NH2 ACETATE SALT D-ALA-BETA-(2-NAPHTHYL)-D-ALA-TRP-D-PHE-LYS AMIDE D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2 (DES-ALA3,D-ALA1,D-2-NAL2)-GHRP-6 (DES-ALA3)-GHRP-2 (DES-ALA3)-GROWTH HORMONE-RELEASING PEPTIDE-2 (DES-ALA3)-KP-102 (DES-ALA3)-PRALMORELIN (DES-ALA8,D-ALA6,D-2-NAL7,D-PHE10)-ALPHA-MSH (6-11) AMIDE H-D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2 H-D-ALA-D-2-NAL-TRP-D-PHE-LYS-NH2 H-D-ALA-D-ALA(2-NAPHTHYL)-TRP-D-PHE-LYS-NH2 GROWTH HORMONE RELEASING PROTEIN-2 (D-ALA1,D-2-NAL2)-GHRP-6 TRIFLUOROACETATE SALT D-ala-B-(2-naphthyl)-D-ala-trp-D-phe-*lys amide -2 (Tetrahydro-2H-pyran-4-yl)methoxy=pyrimidine-4-carboxylic acid Bovine Viral Diarrhea Virus Type 1,2, gp53 (BVDV-1& 2 (Gamma-aminobutyric acid Receptor Subunit gamma-2, GABA(A) Receptor Subunit gamma-2, GABRG2, GABAAR&gamma Macroglobulin &alpha Chikungunya (CHIKV-Env 1 & Laminin &alpha DNA pol &gamma PLC &beta 1, phosphorylated (Y405) GCS-&beta Laminin &gamma IL-13R&alpha