プラルモレリン

プラルモレリン 化学構造式
158861-67-7
CAS番号.
158861-67-7
化学名:
プラルモレリン
别名:
プラルモレリン;プラモレリン;(2S)-6-アミノ-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-2-アミノプロパンアミド]-3-(ナフタレン-2-イル)プロパンアミド]プロパンアミド]-3-(1H-インドール-3-イル)プロパンアミド]-3-フェニルプロパンアミド]ヘキサンアミド;KP-102;D-Ala-3-(2-ナフチル)-D-Ala-L-Ala-L-Trp-D-Phe-L-Lys-NH2
英語名:
GHRP-2
英語别名:
GHRP-2;GHRP;CHRP-2;GHRP-2 ACETATE;GHCA;EIF3A;d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide;-2;-2;p-ERK1
CBNumber:
CB1104514
化学式:
C45H55N9O6
分子量:
817.97
MOL File:
158861-67-7.mol

プラルモレリン 物理性質

融点 :
149 - 151°C
沸点 :
1265.3±65.0 °C(Predicted)
比重(密度) :
1.270±0.06 g/cm3(Predicted)
貯蔵温度 :
−20°C
溶解性:
DMSO(微量、超音波処理)、水(微量)
酸解離定数(Pka):
13.40±0.46(Predicted)
外見 :
凍結乾燥粉末
色:
白からベージュ
安定性::
Hygroscopic
InChIKey:
HRNLPPBUBKMZMT-RDRUQFPZSA-N
SMILES:
C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC1=CC=C2C(=C1)C=CC=C2)NC(=O)[C@@H](C)N
CAS データベース:
158861-67-7(CAS DataBase Reference)

安全性情報

WGK Germany  3

プラルモレリン 価格 もっと(9)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01LKTG2968
GHRP-2
158861-67-7 0.5mg ¥28400 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01LKTG2968
GHRP-2
158861-67-7 1mg ¥48200 2024-03-01 購入
Sigma-Aldrich Japan I2644 インターロイキン-2 ヒト IL-2, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
IL-2, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
158861-67-7 10μG ¥55300 2024-03-01 購入
Sigma-Aldrich Japan I7908 インターロイキン-2 ヒト recombinant, expressed in Pichia pastoris, suitable for cell culture
recombinant, expressed in Pichia pastoris, suitable for cell culture
158861-67-7 10000UNITS ¥76600 2024-03-01 購入
Sigma-Aldrich Japan I2644 インターロイキン-2 ヒト IL-2, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
IL-2, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
158861-67-7 5X10μG ¥260000 2024-03-01 購入

プラルモレリン 化学特性,用途語,生産方法

説明

Pralmorelin (also known as KP-102, GPA-748, GHRP-2, and Growth Hormone Releasing Peptide-2)  is a potent GH secretagogue in development as a diagnostic agent for growth hormone deficiency and for the treatment of pituitary disorders and GH deficiency. It acts as signal molecules that are involved in the control of cell growth and differentiation.

使用

Growth hormone releasing factor. Pralmorelin is a growth hormone secretagogue that acts on the pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone release.

利点

Regulation of blood pressure, increased strength and healing, reduced injury, increased cell rejuvenation, increase in lean muscle mass and stronger bones.

Biochem/physiol Actions

Pralmorelin, also known as Growth hormone-releasing peptide 2 or GHRP-2, is an orally-active, synthetic peptide analogue of met-enkephalin that acts as a ghrelin/growth hormone secretagogue receptor (GHSR) agonist to selectively stimulate the ghrelin receptor and cause growth hormone release. Pralmorelin (GHRP-2) has been used clinically for the assessment of growth hormone deficiency (GHD), It has also been shown to have anti-inflammatory activity.

副作用

No side effects or toxicities were observed. Thus, GHRP-2 is well tolerated and can stimulate GH secretion. Formulations or routes of administration that allow for a longer duration of action will likely be needed to use GHRP-2 in therapy[1].

プラルモレリン 上流と下流の製品情報

原材料

準備製品


プラルモレリン 生産企業

Global( 283)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328
sales03@chemcn.cn China 970 58
Zhuzhou New Peptides Tech Co.,Ltd.
+86-18073326374 +86-18073326374
sales@goodpeptides.com China 56 58
Strong peptide cross-border e-commerce Co. LTD
+undefined13930052870
qt01@qiangtaipharm.com China 84 58
Qingdao Xinli Technology Development Co., Ltd.
+8616632313095
xinlikeji01@qdxlchem.com China 124 58
Sea Biological Co.,LTD
+86-13865152372 +86-13865152372
tim@sea-biol.com China 71 58
Hebei Miaoyin Technology Co.,Ltd
+86-17367732028 +86-17367732028
kathy@hbyinsheng.com China 3512 58
Shanghai Affida new material science and technology center
+undefined15081010295
admin@oudaxin.com China 114 58
Huaian Banting Trading Co., Ltd.
+undefined13102576090
sales5@bantingpeptide.com China 38 58
Shanghai Longyu Biotechnology Co., Ltd.
+8619521488211
info@longyupharma.com China 2541 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12834 58

プラルモレリン  スペクトルデータ(1HNMR)


158861-67-7(プラルモレリン)キーワード:


  • 158861-67-7
  • D-ALANYL-3-(2-NAPHTHALENYL)-D-ALANYL-L-ALANYL-L-TRYPTOPHYL-D-PHENYLALANYL-L-LYSINAMIDE ACETATE ADDUCT
  • GHRP-2 (FREE PEPTIDE)
  • (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-naphthalen-2-yl-propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]-N-[(2R)-2-aminopropanoyl]hexanamide
  • D-Ala-bata-(2-naphthyl)-D-Ala-Trp-D-Phe-Lys amide
  • D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide
  • D-Ala-D-β-Nal-Ala-Trp-D-Phe-Lys-NH2
  • 4-dichloro-1
  • 8-naphthyridine
  • 3-d]pyriMidine TFA
  • 2-trifluoroethyl)thiazole
  • 5-(Tributylstannyl)-2-(2
  • 3-a]pyrazine-3
  • 4]triazolo[4
  • 6-dihydro-[1
  • 7-tert-butyl 3-ethyl 5
  • 7-naphthyridine-3
  • 7-tert-butyl 3-Methyl 5
  • 4]triazine-6-carboxylate
  • ethyl 4-chloropyrrolo[1
  • tert-butyl 3-Methoxy-5
  • 2-trifluoroethyl)cyclopropyl)stannane
  • Tributyl(2-(2
  • Growth HorMone Releasing Hexapeptide-2
  • Monoclonal Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&
  • GH secretagogue receptor
  • GH-releasing peptide receptor
  • GHS receptor
  • Acetic acid ghrelin -2
  • L-Lysinamide, D-alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-
  • PRALMORELIN
  • プラルモレリン
  • プラモレリン
  • (2S)-6-アミノ-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-2-アミノプロパンアミド]-3-(ナフタレン-2-イル)プロパンアミド]プロパンアミド]-3-(1H-インドール-3-イル)プロパンアミド]-3-フェニルプロパンアミド]ヘキサンアミド
  • KP-102
  • D-Ala-3-(2-ナフチル)-D-Ala-L-Ala-L-Trp-D-Phe-L-Lys-NH2
Copyright 2017 © ChemicalBook. All rights reserved