ChemicalBook >> CAS DataBase List >>Rutamycin
Rutamycin
- CAS No.
- 1404-59-7
- Chemical Name:
- Rutamycin
- Synonyms
- A-272;RR-32705;Rutamycin;RRNo-32705;oligomycin D;26-Demethyloligomycin A;RutaMycin, 26-deMethyloligoMycin A, A 272, RR 32705, RutaMycin A;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-,(1S,2'R,4E,5'S,6S,6'S,7S,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-, (1S,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-
- CBNumber:
- CB11120704
- Molecular Formula:
- C44H72O11
- Molecular Weight:
- 777.042
- MDL Number:
- MFCD32640222
- MOL File:
- 1404-59-7.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
| Melting point | 116-119° |
|---|---|
| alpha | D20 -62° (c = 1.36 in CHCl3) |
| Boiling point | 883.4±65.0 °C(Predicted) |
| Density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble |
| form | A lyophilisate |
| pka | 12.52±0.70(Predicted) |
| EWG's Food Scores | 1 |
| FDA UNII | 4736R46V0G |
SAFETY
Risk and Safety Statements
| RIDADR | 2811 |
|---|---|
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LD50 oral in mouse: 800mg/kg |
Rutamycin price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 20184 | Oligomycin D ≥95% | 1404-59-7 | 500μg | $335 | 2024-03-01 | Buy |
| Cayman Chemical | 20184 | Oligomycin D ≥95% | 1404-59-7 | 2.5mg | $751 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | API0012448 | RUTAMYCIN 95.00% | 1404-59-7 | 5MG | $501.12 | 2021-12-16 | Buy |
Rutamycin Chemical Properties,Uses,Production
Description
Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F1FO-ATPase and is used to uncouple oxidative phosphorylation from electron transport. Oligomycin D is reported to inhibit K-Ras plasma membrane localization in MDCK cells with an IC50 value of 3.49 nM and is cytotoxic to SW620 colon cancer cells with an IC50 value of 36 μM.
Uses
Oligomycin D is an inhibitor of mitochondrial F1F0-ATPase.
Uses
Oligomycin D (rutamycin) is macrocyclic lactone belonging to the oligomycin class but identified from different species of Streptomyces in 1961. Like oligomycin A, oligomycin D inhibits mitochondrial F1F0-ATPase and is an important bioprobe to study the organisation of ATPase on the mitochondrial membrane. Oligomycin D exhibits a broad biological profile including antifungal, antitumor and nematocidal activities.
Rutamycin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 38)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30238 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19741 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-18791163155 +86-13119157289 | 13119157289@163.com | China | 2973 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57423 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
1404-59-7(Rutamycin)Related Search:
26-Demethyloligomycin A
A-272
RR-32705
RRNo-32705
RutaMycin, 26-deMethyloligoMycin A, A 272, RR 32705, RutaMycin A
Rutamycin
oligomycin D
Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-,(1S,2'R,4E,5'S,6S,6'S,7S,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-
Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-, (1S,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-
1404-59-7
C44H72O11