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L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI)

CAS No.
99141-91-0
Chemical Name:
L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI)
Synonyms
Ac-Ala-Val-OMe;ZZL-7 / Ac-Ala-Val-OMe;L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI)
CBNumber:
CB111435386
Molecular Formula:
C11H20N2O4
Molecular Weight:
244.29
MDL Number:
MOL File:
99141-91-0.mol
Last updated:2024-07-02 08:54:59

L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI) Properties

Melting point 105 °C
Boiling point 442.1±25.0 °C(Predicted)
Density 1.078±0.06 g/cm3(Predicted)
solubility Soluble to 100 mM in ethanol and to 100 mM in DMSO
pka 13.30±0.46(Predicted)
form Oil
color White to off-white

L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI) Chemical Properties,Uses,Production

Biological Activity

ZZL-7 is a fast-acting antidepressant that enhances 5-HT (serotonin) signaling in forebrain circuits. ZZL-7 disrupts the interaction between the 5-HT transporter (SERT) and neuronal nitric oxide synthase (nNOS) in the dorsal raphe nucleus (DRN), which reduces extracellular 5-HT concentration and down-regulates 5-HT1A receptor auto-activity in the DRN. This reduced auto-inhibition enables increase in firing frequency of serotonergic neurons in the DRN and increases in 5-HT release in the medial hippocampus. ZZL-7 can readily cross the blood-brain barrier.

storage

Store at -20°C

L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI) Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan senwayer century chemical Co.,Ltd
+undefined-27-86652399 +undefined13627115097 market02@senwayer.com China 889 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9874 58
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 eric@peptidego.com China 6526 58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD 0571-87213919 17306812703 3007955328@qq.com China 6213 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9155 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28118 58

View Lastest Price from L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ZZL-7 / Ac-Ala-Val-OMe pictures 2024-03-29 ZZL-7 / Ac-Ala-Val-OMe
99141-91-0
US $0.00 / g 1g 99% min 20 tons Wuhan Senwayer Century Chemical Co.,Ltd

L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI) Spectrum

L-Valine, N-acetyl-L-alanyl-, methyl ester (9CI) Ac-Ala-Val-OMe ZZL-7 / Ac-Ala-Val-OMe 99141-91-0