ChemicalBook >> CAS DataBase List >>6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-α-ethyl-2,3,9-trimethyl-, (αR,6S)-
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-α-ethyl-2,3,9-trimethyl-, (αR,6S)-
- CAS No.
- 2421153-77-5
- Chemical Name:
- 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-α-ethyl-2,3,9-trimethyl-, (αR,6S)-
- Synonyms
- ET-JQ1-OH;6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-α-ethyl-2,3,9-trimethyl-, (αR,6S)-;(2R)-2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.02,?]trideca-2(6),4,7,10,12-pentaen-9-yl]butanoic acid
- CBNumber:
- CB112073510
- Molecular Formula:
- C21H21ClN4O2S
- Molecular Weight:
- 428.94
- MDL Number:
- MOL File:
- 2421153-77-5.mol
Last updated:2023-06-30 15:45:59
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-α-ethyl-2,3,9-trimethyl-, (αR,6S)- Chemical Properties,Uses,Production
Biological Activity
(+)-JQ1 bump, acid functionalized is a BET bromodomain binding analog of (+)-JQ1 that selectively binds single point mutant form of Brd4 (Brd4BD2 L387A). Functionalized with a carboxylic acid group to enable onward chemistry. The position of the carboxylic acid group represents an 'exit vector' allowing modification without interfering with compound binding ability.
storage
Store at -20°C
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-α-ethyl-2,3,9-trimethyl-, (αR,6S)- Preparation Products And Raw materials
Raw materials
Preparation Products
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-α-ethyl-2,3,9-trimethyl-, (αR,6S)- Suppliers
Global( 5)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou J&H Chemical Co., Ltd. | 0571-+86-571-87396432 | sales@jhechem.com | China | 11280 | 59 |
Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1382 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23962 | 58 |
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. | 025-66061636 18013972705 | qqyang@aikonchem.com | China | 8263 | 58 |
Elucigen bio | 13501719342 | wayne.zheng@elucigenbio.com | China | 4587 | 58 |
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-α-ethyl-2,3,9-trimethyl-, (αR,6S)-
ET-JQ1-OH
(2R)-2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.02,?]trideca-2(6),4,7,10,12-pentaen-9-yl]butanoic acid
2421153-77-5