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Guanosine-5'-diphosphate disodium salt

Guanosine-5'-diphosphate disodium salt Structure
Guanosine-5'-diphosphate disodium salt structure
CAS No.
7415-69-2
Chemical Name:
Guanosine-5'-diphosphate disodium salt
Synonyms
GDP;GDP.Na2;GDP*2Na;GDP, NA2H;5'-GDP-Na2;5'-GDP 3NA;5'-GDP,2Na;Einecs 231-026-2;en pyrophosphate);Sodium (2R,3R,4R,5R)
CBNumber:
CB1124550
Molecular Formula:
C10H16N5NaO11P2
Molecular Weight:
467.2
MDL Number:
MFCD00066538
MOL File:
7415-69-2.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24
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Guanosine-5'-diphosphate disodium salt Properties

Melting point >280°C (dec.)
storage temp. -20°C
solubility H2O: 50 mg/mL, clear, colorless
form Powder
color White
biological source Porcine brain
microbial (Corynebacterium sp)
synthetic
Water Solubility Soluble in water
Stability Hygroscopic
InChIKey PVMPTWQLNDHIEV-NGPBCCOENA-N
SMILES O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=NC2C(NC(N)=NC1=2)=O)O.[NaH] |&1:1,2,3,15,r|
UNSPSC Code 41106305
NACRES NA.51

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36/37/39-27-26
WGK Germany  3
F  3-10-21
HS Code  29349990

Guanosine-5'-diphosphate disodium salt price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 51060 Guanosine 5′-diphosphate disodium salt ≥90% (HPLC) 7415-69-2 100mg $203 2024-03-01 Buy
Sigma-Aldrich 51060 Guanosine 5′-diphosphate disodium salt ≥90% (HPLC) 7415-69-2 500mg $700 2024-03-01 Buy
Alfa Aesar J61646 Guanosine-5'-diphosphate disodium salt 7415-69-2 100mg $140 2024-03-01 Buy
Alfa Aesar J61646 Guanosine-5'-diphosphate disodium salt 7415-69-2 500mg $488 2024-03-01 Buy
Usbiological 296168 Guanosine 5'-Diphosphate Disodium Salt 7415-69-2 1g $319 2021-12-16 Buy
Product number Packaging Price Buy
51060 100mg $203 Buy
51060 500mg $700 Buy
J61646 100mg $140 Buy
J61646 500mg $488 Buy
296168 1g $319 Buy

Guanosine-5'-diphosphate disodium salt Chemical Properties,Uses,Production

Uses

Guanosine 5'-diphosphate disodium salt is a useful research chemical.

Uses

Guanosine-5'-diphosphate disodium salt is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors. It is also used to study cell signaling processes mediate by guanine nucleotide exchange factors.

General Description

Guanosine 5′-diphosphate (GDP) is a purine nucleotide and is interconvertible to guanosine by the action of ectonucleotidases and by nucleoside phosphorylase into guanine. GDP is majorly acted upon by 5′‐ectonucleotidases in neuronal cells.

Biochem/physiol Actions

Guanosine based nucleosides play a key role in multiple cellular processes and generation growth factors. Elevated levels of guanosine 5′-diphosphate (GDP) is associated with the pathogenesis of neurological disorders. GDP is bound to G protein . G protein coupled receptors (GPCRs) activate G proteins by exchanging the bound GDP to GTP. GDP is potent inhibitor agent of hepcidin- ferroportin complex and may be effective for promoting erythropoiesis and treating anemia of inflammation(AI).

in vivo

Guanosine 5'-diphosphate disodium salt (30 mg/kg, i.p., a single dose for 24 h) combined with FeSO4 (2 mg/kg, i.p., a single dose for 24 h) suppresses the iron storage ferritin level, thus preventing Hepcidin (HY-P70400)-induced internalization of FPN with increased iron absorption in normal mice[2].
Guanosine 5'-diphosphate disodium salt (30 mL/kg, i.p., three times a week for two weeks) can improve turpentine-induced inflammatory anemia in mice[1].

Animal Model:Male BALB/c mice[2].
Dosage:30 mL/kg
Administration:Intraperitoneal injection (i.p.)
Result:Increased hemoglobin levels and serum iron levels in the long-term dosing model.
Decreased Hamp mRNA expression, and spleen iron content was reduced by 46% in the short-term dosing model.

IC 50

Human Endogenous Metabolite

Guanosine-5'-diphosphate disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

Guanosine-5'-diphosphate disodium salt Suppliers

Global( 253)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Meiya Pharmaceutical Co Ltd
+86-021-33686691 +8618001850931 sales@meiyapharm.com China 58 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531157085 abby@chuanghaibio.com China 8808 58
Hebei Mujin Biotechnology Co.,Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12809 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21628 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29859 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Shanghai Longyu Biotechnology Co., Ltd. 		+8619521488211 info@longyupharma.com China 2555 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49732 58
Supplier Advantage
Hangzhou Meiya Pharmaceutical Co Ltd
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Mujin Biotechnology Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
BOC Sciences 		58
Shanghai Longyu Biotechnology Co., Ltd. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58

View Lastest Price from Guanosine-5'-diphosphate disodium salt manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Guanosine-5'-diphosphate disodium salt pictures 2025-04-24 Guanosine-5'-diphosphate disodium salt
7415-69-2
 US $0.00-0.00 / kg 1kg 98%min 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
Guanosine 5’-diphosphate disodium salt（GDP-Na2） pictures 2025-04-24 Guanosine 5’-diphosphate disodium salt（GDP-Na2）
7415-69-2
 US $0.00-0.00 / kg 1kg ≥95.0% 1000 kg Hangzhou Meiya Pharmaceutical Co Ltd
Guanosine 5'-diphosphate disodium salt;GDP; GDP-Na2; 5'-GDP-Na2 pictures 2025-04-23 Guanosine 5'-diphosphate disodium salt;GDP; GDP-Na2; 5'-GDP-Na2
7415-69-2
 US $0.00-0.00 / g 10g 99.0%min. HPLC 10000 HangZhou RunYan Pharma Technology Co.,LTD.

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