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Oxyphenonium

CAS No.
14214-84-7
Chemical Name:
Oxyphenonium
Synonyms
Diethylmethyl[2-(hydroxyphenylcyclohexylacetoxy)ethyl]aminium;2-[Cyclohexyl(hydroxy)(phenyl)acetoxy]-N,N-diethyl-N-methylethanaminium
CBNumber:
CB11379876
Molecular Formula:
C21H34NO3+
Molecular Weight:
348.51
MDL Number:
MOL File:
14214-84-7.mol
Last updated:2023-05-04 17:34:33

Oxyphenonium Properties

FDA UNII D2G5508Y7I

Oxyphenonium Chemical Properties,Uses,Production

Originator

A-Spasm ,Acme Laboratories Ltd.

Definition

ChEBI: 2-(2-cyclohexyl-2-hydroxy-1-oxo-2-phenylethoxy)ethyl-diethyl-methylammonium is an acylcholine.

Manufacturing Process

1 mol cycloxehylhydroxyphenylacetic acid methyl ester was mixed with 1 mol 2-diethylaminoethanol in presence of 1 mol sodium methylate to give cycloxehylhydroxyphenylacetic acid 2-diethylamino-ethyl ester.
5 parts by weight of it was dissolved in 50 volumes glacial acetic acid and a gaseous methyl bromide was introduced. The mixture was heated to about 50°C and crystallization of cycloxehylhydroxyphenylacetic acid diethylaminoethyl ester methyl bromide has shortly after begun. On cooling the crystals was filtered off and recrystallized from mixture of ethyl acetate ant a little ethanol to give the oxyphenonium bromide. MP: 189°-191°C.

brand name

Antrenyl (Novartis).

Therapeutic Function

Anticholinergic, Spasmolytic

Oxyphenonium Preparation Products And Raw materials

Raw materials

Preparation Products

Oxyphenonium Suppliers

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2-[Cyclohexyl(hydroxy)(phenyl)acetoxy]-N,N-diethyl-N-methylethanaminium Diethylmethyl[2-(hydroxyphenylcyclohexylacetoxy)ethyl]aminium 14214-84-7