ChemicalBook >> CAS DataBase List >>Isosorbide
Isosorbide
- CAS No.
- 652-67-5
- Chemical Name:
- Isosorbide
- Synonyms
- (3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diol;at101;IsMotic;Isosorbide (75% solution, 1 g);ucitoL;isobide;hydronol;Isosorbid;NSC 40725;devicoran
- CBNumber:
- CB1162705
- Molecular Formula:
- C6H10O4
- Molecular Weight:
- 146.14
- MDL Number:
- MFCD00064827
- MOL File:
- 652-67-5.mol
- MSDS File:
- SDS
Last updated:2024-12-18 14:07:02
| Melting point | 60-63 °C (lit.) |
|---|---|
| Boiling point | 175°C/2mmHg(lit.) |
| alpha | 42 º (c=3, H2O) |
| Density | 1.0945 (rough estimate) |
| vapor pressure | 0.007Pa at 20℃ |
| refractive index | 45 ° (C=5, H2O) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| pka | 13.17±0.40(Predicted) |
| form | Crystals, Crystalline Solid or Mass |
| color | Off-white to light yellow or beige |
| optical activity | [α]20/D +45.2°, c = 3 in H2O |
| Water Solubility | Soluble in alcohols, water and ketones. |
| Sensitive | Hygroscopic |
| Merck | 14,5224 |
| BRN | 80510 |
| InChIKey | KLDXJTOLSGUMSJ-JGWLITMVSA-N |
| LogP | -1.39 at 20℃ |
| CAS DataBase Reference | 652-67-5(CAS DataBase Reference) |
| FDA UNII | WXR179L51S |
| EPA Substance Registry System | D-Glucitol, 1,4:3,6-dianhydro- (652-67-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227 | |||||||||
| Precautionary statements | P501-P210-P280-P370+P378-P403+P235 | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | LZ4380000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29349990 | |||||||||
| Hazardous Substances Data | 652-67-5(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
Isosorbide price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 329207 | Dianhydro-D-glucitol 98% | 652-67-5 | 100g | $91.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1352008 | Isosorbide United States Pharmacopeia (USP) Reference Standard | 652-67-5 | 1g | $436 | 2024-03-01 | Buy |
| TCI Chemical | I0407 | Isosorbide >98.0%(GC) | 652-67-5 | 25g | $28 | 2024-03-01 | Buy |
| TCI Chemical | I0407 | Isosorbide >98.0%(GC) | 652-67-5 | 100g | $54 | 2024-03-01 | Buy |
| Alfa Aesar | A13989 | D-Isosorbide, 98% | 652-67-5 | 50g | $39.3 | 2024-03-01 | Buy |
Isosorbide Chemical Properties,Uses,Production
Chemical Properties
off-white to light yellow or beige crystals,
Uses
pharmaceutical intermediate for dimethyl ether and mono- and dinitrate derivatives; the nitrate esters find use as vasodilators and coronary disease therapeutics.
Uses
D-Isosorbide is used as a reagent in the preparation of detergents, agrochemicals, cleansers, cosmetics and vasodilators. It is also employed as a pharmaceutical intermediate for dimethyl ether and mono- and dinitrate derivatives, which is used as vasodilators and coronary disease therapeutics. It is used in the treatment of hydrocephalus and glaucoma. It finds application as a building block for polymers like polycarbonates and polyesters.
Uses
Isosorbide is a reagent widely used to prepare detergents, cleansers, cosmetics, agrochemicals and vasodilators.
Definition
A polyol with a hydroxyl group attached to each of two cis-oriented saturated furan rings. Intermediate for pharmaceuticals. Combustible.
brand name
Ismotic (Alcon).
Biological Functions
emergency treatment of acute angle-closure glaucoma. It should not be confused with isosorbide dinitrate, an antianginal drug.
Flammability and Explosibility
Non flammable
Clinical Use
Isosorbide is basically a bicyclic form of sorbitol that is used orally to cause a reduction in intraocular pressure in glaucoma cases. Although a diuretic effect is noted, its ophthalmologic properties are its primary value.
Isosorbide Preparation Products And Raw materials
Global( 453)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Hongbaifeng Industry And Trade Co., Ltd | +86-531-87333789 +86-15066110813 | hongbaifeng@live.cn | China | 2 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8808 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12834 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1001 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
View Lastest Price from Isosorbide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-23 | Isosorbide
652-67-5
|
US $120.00 / kg | 1kg | 99% | 10ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-11-19 | Isosorbide
652-67-5
|
US $56.00 / g | 97.28% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-14 | Isosorbide
652-67-5
|
US $14.50 / KG | 25KG | 98% | 1-200mt | Baoji Guokang Bio-Technology Co., Ltd. |
-
- Isosorbide
652-67-5
- US $120.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Isosorbide
652-67-5
- US $56.00 / g
- 97.28%
- TargetMol Chemicals Inc.
-
- Isosorbide
652-67-5
- US $14.50 / KG
- 98%
- Baoji Guokang Bio-Technology Co., Ltd.
652-67-5(Isosorbide)Related Search:
Isosorbide-2-Acetate
ISOSORBIDE MONONITRATE,ISOSORBIDE 5-NITRATE,ISOSORBIDE 5-MONONITRATE, 98.5%,ISOSORBIDE MONO ACETATE,ISOSORBIDE 5-MONONITRATE,5-ISOSORBIDE MONONITRATE
ISOSORBIDE 2-MONONITRATE,ISOSORBIDE 2-MONONITRATE 99-101.0%,isosorbide2-nitrat
Isostearic Acid
isononyl alcohol
1of4
Dianhydro-D-glucitol 98%
1,4:3,6-DIANHYDRO-D-SORBITOL
1,4:3,6-DIANHYDROGLUCITOL
1,4:3,6-DIANHYDROSORBITOL
1,4:3,6-DIANHYDRO-D-GLUCITOL
D-ISOSORBIDE
DIANHYDRO-D-GLUCITOL
DIANHYDRO-D-SORBITOL
ISOSORBIDE
(3S,3AR,6R,6AR)-HEXAHYDRO-FURO[3,2-B]FURAN-3,6-DIOL
1,4:3,6-dianhydro-d-glucito
Isosorbide, typically 98%
1,4:3,6-Dianhydro-D-sorbitol, D-Isosorbide
Isosorbide,98%
Dianhydro-D-glucitol,1,4:3,6-Dianhydro-D-sorbitol, D-Isosorbide
Isosorbide, 98% 100GR
1,4:3,6-Dianhydroglucitol
1,4:3,6-Dianhydrosorbitol
1,4,3,6,5-Dianhydrosorbitol
ISOSONBIDE(1,4:3,6-DIANHYDRO-D-SORHITOL)
Isosorbid
D-Glucitol, 1,4:3,6-dianhydro-
D-Glucitol, 1,4:3,6-dianhydro- (9CI)
NSC 40725
1,4,3,6-DIANHYDRO-D-GLUCITOL D-ISOSORBIDE
4:3,6-dianhydro-d-glucito
d-1,4:3,6-dianhydroglucitol
devicoran
hydronol
isobide
Isosorbide,typically98%
Isosorbide Isosorbide
Isosorbide>
Isosorbide, 97%, reagent grade
Dianhydro-D-g
ucitoL
Dianhydro-D-gL
Isosorbide USP/EP/BP
Isosorbide Impurity 21
Isosorbide Impurity 22
IsosorbideQ: What is
Isosorbide Q: What is the CAS Number of
Isosorbide Q: What is the storage condition of
Isosorbide Q: What are the applications of
Isosorbide
Isosorbide (75% solution, 1 g) (1352008)
Isosorbide (75% solution, 1 g)
IsMotic
(3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diol
at101
1,4：3,6-dianhydro-D-[UL-13C6]glucitol
Isosorbitol
(3S, 3AR, 6R, 6AR) - Hexahydrogen - [3,2-B] furan-3,6-diol)
Isosorbide
1,4:3,6-Dianhydro-D-glucitol
Isosorbide in Acetonitrile
lsosorbide
652-67-5
662-67-5
Carbohydrate Synthesis
Specialty Synthesis
Monosaccharides
Carbohydrates & Derivatives
Heterocycles