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POLY(N-ISOPROPYL ACRYLAMIDE)

CAS No.
25189-55-3
Chemical Name:
POLY(N-ISOPROPYL ACRYLAMIDE)
Synonyms
PNIPAM;CHEBI:53234;nipam polymer;POLY(N-ISOPROPYL ACRYLAMIDE);N-ISO-PROPYLACRYLAMIDE POLYMER;Poly(N-isopropylacrylamide) (PNiPAM);Poly(N-isopropylacrylamide) Mn ~40,000;n-(1-methylethyl)-2-propenamidhomopolymer;poly(N-isopropylacrylamide) macromolecule;poly(n-iso-propylacrylamide)(mw20000-25000)
CBNumber:
CB1188228
Molecular Formula:
C6H11NO
Molecular Weight:
113.15764
MDL Number:
MFCD00284282
MOL File:
25189-55-3.mol
MSDS File:
SDS
Last updated:2024-07-02 17:04:22

POLY(N-ISOPROPYL ACRYLAMIDE) Properties

Melting point 96 °C(lit.)
Tg 130
Density 1.386 g/cm3
storage temp. -20°C
form powder
color white to off-white
Viscosity 1.0(Inherent viscosity)
EPA Substance Registry System 2-Propenamide, N-(1-methylethyl)-, homopolymer (25189-55-3)

SAFETY

Risk and Safety Statements

WGK Germany  1

POLY(N-ISOPROPYL ACRYLAMIDE) price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 900188 Poly(N-isopropyl acrylamide) NHS ester end functionalized, average Mn 5,000 25189-55-3 1g $368 2024-03-01 Buy
Sigma-Aldrich 535311 Poly(N-isopropyl acrylamide) Mn ~40,000 25189-55-3 10g $821 2024-03-01 Buy
Sigma-Aldrich 901422 Poly(N-isopropylacrylamide) average Mn 85,000 25189-55-3 10G $352 2023-06-20 Buy
Sigma-Aldrich 806366 Poly(N-isopropyl acrylamide) carboxylic acid, thiol 25189-55-3 1G $503 2023-06-20 Buy
scipoly 963 Poly(N-isopropyl acrylamide) 25189-55-3 10g $36 2024-07-03 Buy
Product number Packaging Price Buy
900188 1g $368 Buy
535311 10g $821 Buy
901422 10G $352 Buy
806366 1G $503 Buy
963 10g $36 Buy

POLY(N-ISOPROPYL ACRYLAMIDE) Chemical Properties,Uses,Production

Chemical Properties

mp 96°C phase transitions at 32°C to insoluble phase

Uses

PolyNIPAM is a stimuli-responsive polymer. The low PDI means that the distribution of chain lengths is narrow which will typically lead to better reproducibility. This polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The carboxylic acid functional group can be used to conjugate a variety of biomolecules to the polymer chain.

Uses

Poly(N-iso-propyl acrylaMide) can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.

Definition

ChEBI: An acrylic macromolecule, arising from poymerisation of N-isopropylamide.

General Description

Poly(N-isopropylacrylamide) (PNIPAM) is a temperature-responsive polymer used in biomedical research applications. PNIPAM undergoes a reversible, lower critical solution temperature (LCST) phase transition when heated above 32 °C, transitioning from a soluble to an insoluble material. PNIPAM is also frequently crosslinked to yield hydrogels with reversible, thermal shrinking and swelling. Poly(N-isopropylacrylamide) is also readily functionalized and has been used as the hydrophilic block in the synthesis of thermoresponsive, amphiphilic block copolymers. Due to the similarity in temperature between the LCST of PNIPAM and the temperature of the human body, PNIPAM materials have been frequently utilized in tissue engineering and controlled drug delivery research applications.

Solubility in organics

Acetone, THF, water (cold)

POLY(N-ISOPROPYL ACRYLAMIDE) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 77)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Dorne Chemical Technology co. LTD
+86-86-13583358881 +8618560316533 Ethan@dornechem.com China 3095 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 22883 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9639 58
Henan Alfa Chemical Co., Ltd
+86-18339805032; +8618339805032 alfa4@alfachem.cn China 13227 58
Alfa Chemistry
Info@alfa-chemistry.com United States 24072 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
PT CHEM GROUP LIMITED
peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49979 58

View Lastest Price from POLY(N-ISOPROPYL ACRYLAMIDE) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
POLY(N-ISOPROPYL ACRYLAMIDE)  pictures 2022-07-22 POLY(N-ISOPROPYL ACRYLAMIDE)
25189-55-3
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
n-(1-methylethyl)-2-propenamidhomopolymer poly(n-iso-propylacrylamide)(mw20000-25000) Poly(N-isopropylacrylaMide) Mw 20,000-40,000 Poly(N-isopropylacrylaMide), carboxylic acid terMinated average Mn 10,000 nipam polymer 2-Propenamid, N-(1-methylethyl)-, Homopolymer 2-Propenamide, N-(1-methylethyl)-, homopolymer n-(1-methylethyl)-2-propenamid homopolymer N-(1-Methylethyl)-2-propenamide homopolymer Poly(N-isopropylacrylamide),NIPAM polymer, PNIPAM, Polyacrylamide, polyNIPAM PNIPAM Poly(N-isopropylacrylamide) Mn 20,000-40,000 Poly(N-isopropylacrylamide) average Mn 30,000 N-ISO-PROPYLACRYLAMIDE POLYMER POLY(N-ISOPROPYL ACRYLAMIDE) 2-Propenamide,N-(1-methylethyl)-,homopolymer poly(N-isopropylacrylamide) macromolecule Poly(N-isopropylacrylamide) average Mn 85,000 POLY(N-ISOPROPYL ACRYLAMIDE) ISO 9001:2015 REACH Poly(N-isopropylacrylamide) Mn ~40,000 Poly(N-isopropylacrylamide) (PNiPAM) CHEBI:53234 25189-55-3 Acrylamides Acrylics Biomaterials Hydrogels and Crosslinked Polymers Hydrophilic Polymers Materials Science Polymer Science Polymers