ChemicalBook >> CAS DataBase List >>4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
- CAS No.
- 300827-87-6
- Chemical Name:
- 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
- Synonyms
- D2069;Desvenlafaxine HCl;Venlafaxine Impurity 16;Desvenlafaxine hydrochloride;4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
- CBNumber:
- CB12101937
- Molecular Formula:
- C16H25NO2HCl
- Molecular Weight:
- 0
- MDL Number:
- MFCD11045287
- MOL File:
- 300827-87-6.mol
Last updated:2023-07-05 08:28:19
Melting point | >75°C (dec.) |
---|---|
storage temp. | 2-8°C |
solubility | DMSO: >20mg/mL |
form | powder |
color | white to off-white |
Stability | Hygroscopic |
FDA UNII | 3TP4E4F972 |
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | D2069 | Desvenlafaxine hydrochloride ≥98% (HPLC), powder | 300827-87-6 | 10mg | $233 | 2024-03-01 | Buy |
Sigma-Aldrich | D2069 | Desvenlafaxine hydrochloride ≥98% (HPLC), powder | 300827-87-6 | 50mg | $711 | 2024-03-01 | Buy |
TRC | D297928 | Desvenlafaxine hydrochloride | 300827-87-6 | 50mg | $525 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008432 | DESVENLAFAXINE HYDROCHLORIDE 95.00% | 300827-87-6 | 10MG | $713.71 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008432 | DESVENLAFAXINE HYDROCHLORIDE 95.00% | 300827-87-6 | 50MG | $1220.03 | 2021-12-16 | Buy |
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Chemical Properties,Uses,Production
Uses
Desvenlafaxine Hydrochloride is a major active metabolite of venlafaxine (V120000), which is a slective serotonin noradrenaline reuptake inhibitor and used as an antidepressant.
Uses
Desvenlafaxine hydrochloride has been used to evaluate if its occurrence in drinking water at environmental concentrations could induce neuronal gene expression.
Biochem/physiol Actions
Desvenlafaxine hydrochloride is a dual SERT/NET reuptake inhibitor. It is a major active metabolite of venlafaxine (#542); brain penetrant; Ki = 40 nM and 122 nM for hSERT and hNET, respectively (weak binding at the hDAT). Inhibition of [3H]5-HT or [3H]NE uptake for the hSERT or hNET produced IC50 values of 47 and 531 nM.
![99300-78-4](/CAS/GIF/99300-78-4.gif)
![300827-87-6](/CAS/GIF/300827-87-6.gif)
Synthesis of 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride from Venlafaxine hydrochloride
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Preparation Products And Raw materials
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Suppliers
Global( 23)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
SynAsst Chemical. | 021-60343070 | China | 12742 | 55 | |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 | wxf@sungening.com | China | 9592 | 60 |
Guangzhou Dreampharm Biotechnology Co., Ltd. | 020-36607679 17825480238 | 3008233717@qq.com | China | 9875 | 12 |
300827-87-6(4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride)Related Search:
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1of3
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
Desvenlafaxine hydrochloride
Desvenlafaxine HCl
D2069
Venlafaxine Impurity 16
300827-87-6