DISUCCINIMIDYL SUBERATE
- CAS No.
- 68528-80-3
- Chemical Name:
- DISUCCINIMIDYL SUBERATE
- Synonyms
- DSS;DSS Crosslinker;Disuccinimidyl subera;DISUCCINIMIDYL SUBERATE;DSS Disuccinimidyl subera;Disuccinimidyl subera(DSS);DISUCCINIMIDYL OCTANEDIOATE;Di(N-succinimidyl) Suberate;Bis-(N-succinimidyl)-suberate;Di(N-succinimidyl)Suberate>
- CBNumber:
- CB1219157
- Molecular Formula:
- C16H20N2O8
- Molecular Weight:
- 368.34
- MDL Number:
- MFCD00049059
- MOL File:
- 68528-80-3.mol
- MSDS File:
- SDS
Melting point | 169-170°C |
---|---|
Boiling point | 513.5±60.0 °C(Predicted) |
Density | 1.295 g/cm3 |
storage temp. | 2-8°C |
solubility | chloroform: 50 mg/mL |
form | powder |
color | White to Almost white |
Water Solubility | Insoluble in water. Soluble in chloroform: 50 mg/mL. |
InChIKey | ZWIBGKZDAWNIFC-UHFFFAOYSA-N |
CAS DataBase Reference | 68528-80-3 |
FDA UNII | V9WYZ7QMDT |
UNSPSC Code | 12352100 |
NACRES | NA.21 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P280-P304+P340-P305+P351+P338 | |||||||||
Safety Statements | 24/25 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 29171900 | |||||||||
NFPA 704 |
|
DISUCCINIMIDYL SUBERATE price More Price(44)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | S1885 | Suberic acid bis(N-hydroxysuccinimide ester) ≥95%, powder | 68528-80-3 | 1g | $132 | 2024-03-01 | Buy |
Sigma-Aldrich | S1885 | Suberic acid bis(N-hydroxysuccinimide ester) ≥95%, powder | 68528-80-3 | 5g | $352 | 2024-03-01 | Buy |
TCI Chemical | D3895 | Di(N-succinimidyl) Suberate >98.0%(HPLC)(N) | 68528-80-3 | 1g | $94 | 2024-03-01 | Buy |
TCI Chemical | D3895 | Di(N-succinimidyl) Suberate >98.0%(HPLC)(N) | 68528-80-3 | 5g | $324 | 2024-03-01 | Buy |
Alfa Aesar | H51771 | Disuccinimidyl suberate, 97% | 68528-80-3 | 500mg | $74.65 | 2024-03-01 | Buy |
DISUCCINIMIDYL SUBERATE Chemical Properties,Uses,Production
Description
DSS Crosslinker is a membrane permeable, noncleavable crosslinker. The NHS ester groups are reactive toward primary amines.
Uses
Disuccinimidyl suberate is a homobifunctional amine-reactive crosslinker. It is usually coupled to molecules containing primary amines via amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates an 8-atom spacer arm.
Uses
Suberic acid bis(N-hydroxysuccinimide ester) has been:
- supplemented in pierce lysis buffer used for immunoprecipitation
- used to conjugate the oligonucleotide standards to gelatin
- used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers
Uses
Disuccinimidyl suberate (DSS) is a bifunctional cross-linking reagent which contains two N-hydroxysuccinimide esters that are reactive toward primary amines. DSS is membrane-permeable and is commonly used to cross-link proteins in intact cells.
General Description
Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker.
reaction suitability
reagent type: cross-linking reagent
IC 50
Non-cleavable Linker
DISUCCINIMIDYL SUBERATE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12185 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32197 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15393 | 58 |
Alfa Chemistry | info@alfa-chemistry.com | United States | 2344 | 58 |
View Lastest Price from DISUCCINIMIDYL SUBERATE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-11-19 | DSS Crosslinker
68528-80-3
|
US $41.00-57.00 / mg | 99.72% | 10g | TargetMol Chemicals Inc. | ||
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2021-07-13 | DISUCCINIMIDYL SUBERATE
68528-80-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
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2021-07-09 | DISUCCINIMIDYL SUBERATE
68528-80-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- DSS Crosslinker
68528-80-3
- US $41.00-57.00 / mg
- 99.72%
- TargetMol Chemicals Inc.
-
- DISUCCINIMIDYL SUBERATE
68528-80-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- DISUCCINIMIDYL SUBERATE
68528-80-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd