2-Maleimido acetic acid
- CAS No.
- 25021-08-3
- Chemical Name:
- 2-Maleimido acetic acid
- Synonyms
- 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid;NSC 266055;N-Maleoylglycine;N-MaleiMidoglycine;N,N-maleoyl-glycine;MALEIMIDOACETIC ACID;2-maleimide acetic acid;2-MALEIMIDO ACETIC ACID;N-(CarboxyMethyl)MaleiMide;2-MALEIMIDO ACETIC ACID 97%
- CBNumber:
- CB61118111
- Molecular Formula:
- C6H5NO4
- Molecular Weight:
- 155.11
- MDL Number:
- MFCD00457254
- MOL File:
- 25021-08-3.mol
Melting point | 114 °C(Solv: chloroform (67-66-3)) |
---|---|
Boiling point | 376.7±25.0 °C(Predicted) |
Density | 1.578±0.06 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | soluble in DMSO, Methanol |
form | powder to crystal |
pka | 3.31±0.10(Predicted) |
color | White to Almost white |
InChI | InChI=1S/C6H5NO4/c8-4-1-2-5(9)7(4)3-6(10)11/h1-2H,3H2,(H,10,11) |
InChIKey | GBKPNGVKZQBPCZ-UHFFFAOYSA-N |
SMILES | N1(CC(O)=O)C(=O)C=CC1=O |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
HS Code | 2925.19.4200 | |||||||||
NFPA 704 |
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2-Maleimido acetic acid price More Price(26)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | M3143 | 2-Maleimidoacetic Acid >98.0%(HPLC)(T) | 25021-08-3 | 50mg | $65 | 2024-03-01 | Buy |
TCI Chemical | M3143 | 2-Maleimidoacetic Acid >98.0%(HPLC)(T) | 25021-08-3 | 250mg | $191 | 2024-03-01 | Buy |
TRC | M124990 | MaleimidoaceticAcid | 25021-08-3 | 250mg | $135 | 2021-12-16 | Buy |
Matrix Scientific | 119970 | 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid 95+% | 25021-08-3 | 1g | $810 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0155638 | 2-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)ACETIC ACID 95.00% | 25021-08-3 | 1G | $925.31 | 2021-12-16 | Buy |
2-Maleimido acetic acid Chemical Properties,Uses,Production
Chemical Properties
White to Almost white powder to crystal or Pale Yellow Solid.
Uses
Maleimidoacetic Acid (CAS# 25021-08-3) is a heterocyclic organic compound that has a variety of uses in organic synthesis. It contains both a maleimide and carboxylic acid functional group, making it a versatile reagent for coupling reactions with amine-containing compounds.
Application
2-Maleimido acetic acid is a maleimide-containing ligand that could be used to produce the cisplatin-based Pt(IV) complexes (OC-6-44)-diamminedichlorido(ethanolato)(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV) and (OC-6-44)-acetatodiamminedichlorido(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV). The Pt(IV) complexes are considered to act as antitumor prodrugs and their in vivo activity can be improved by exploiting drug targeting and delivery strategies[1]. In this case, conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition.
References
[1] Gabano E, et al. Conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition. Inorganica Chimica Acta, 2019; 488: 195-200.
2-Maleimido acetic acid Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4242 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
Shanghai Gubang New Materail Technology Co. LTD | 21-51317962 +8618721305404 | 16728589@qq.com | CHINA | 272 | 58 |
Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9320 | 58 |
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
View Lastest Price from 2-Maleimido acetic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2021-07-13 | 2-Maleimido acetic acid
25021-08-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
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2021-07-09 | 2-Maleimido acetic acid
25021-08-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
![]() |
2020-01-09 | 2-Maleimido acetic acid
25021-08-3
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- 2-Maleimido acetic acid
25021-08-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 2-Maleimido acetic acid
25021-08-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 2-Maleimido acetic acid
25021-08-3
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co
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