ELASTATINAL
- CAS No.
- 51798-45-9
- Chemical Name:
- ELASTATINAL
- Synonyms
- ELASTATINAL;AIDS-006470;Leu-co-cpd-Gln-Ala-h;ELASTATINAL USP/EP/BP;elastatinal from microbial source;N-[-N-ALPHA-CARBONYL-CPD-GLN-ALA-AL]-LEU;l-glutamamide,l-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl-n-(((1-carboxy-3-m;N-[(S)-1-CARBOXYISOPENTYL]CARBAMOYL-ALPHA-[2-IMINOHEXAHYDRO-4(S)-PYRIMIDYL-(S)-GLYCYL-(S)-GLUTAMINYL-(S)-ALANINAL];Nα-[2-(2-Amino-1,4,5,6-tetrahydropyrimidin-4-yl)-N-[[(1-carboxy-3-methylbutyl)amino]carbonyl]-L-glycyl]-N1-(1-methyl-2-oxoethyl)-L-glutaminamide;L-Glutamamide, (2S)-2-(4S)-2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl-N-(1S)-1-carboxy-3-methylbutylaminocarbonylglycyl-N1-(1S)-1-methyl-2-oxoethyl-
- CBNumber:
- CB1249000
- Molecular Formula:
- C21H36N8O7
- Molecular Weight:
- 512.56
- MDL Number:
- MFCD00151180
- MOL File:
- 51798-45-9.mol
- MSDS File:
- SDS
storage temp. | -20°C |
---|---|
solubility | H2O: 20 mg/mL, clear, yellow |
form | Yellow solid. |
color | off-white |
BRN | 873543 |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month. |
FDA UNII | LX4Y75DOA7 |
ELASTATINAL price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | E0881 | Elastatinal microbial | 51798-45-9 | 5mg | $181 | 2024-03-01 | Buy |
Sigma-Aldrich | E0881 | Elastatinal microbial | 51798-45-9 | 10mg | $330 | 2024-03-01 | Buy |
Alfa Aesar | J61120 | Elastatinal | 51798-45-9 | 5mg | $147 | 2023-06-20 | Buy |
Alfa Aesar | J61120 | Elastatinal | 51798-45-9 | 25mg | $432 | 2021-12-16 | Buy |
Cayman Chemical | 22288 | Elastatinal ≥95% | 51798-45-9 | 5mg | $93 | 2024-03-01 | Buy |
ELASTATINAL Chemical Properties,Uses,Production
Description
Elastatinal is a potent inhibitor of pancreatic elastase (Ki = 240 nM) that is produced by various species of Actinomycetes. It more strongly inhibits pancreatic elastase versus the leukocyte-derived enzyme. Elastatinal reduces electrophoretic mobilities of 2A proteinases from poliovirus and human rhinovirus 14 in a dose-dependent manner, indicating substrate recognition by 2A proteinases is similar to that of pancreatic elastases. It can also inhibit elastase-like protease collagenolytic protease from C. maenas digestive glands.
Uses
Elastatinal is an elastase inhibitor.
Biochem/physiol Actions
Potent, irreversible elastase inhibitor. Elastatinal is a much stronger inhibitor of elastase from pancreas than from leucocytes.
References
1) Umezawa et al. (1973), Letter: Elastatinal, a new elastase inhibitor produced by actinomycetes; J. Antibiotics, 26 787 2) Nakajima et al. (1992), Identification of elastase as a secretory protease from cultured rat microglia; J. Neurochem., 58 1401 3) Molla et al. (1993), Inhibition of proteolytic activity of poliovirus and rhinovirus 2A proteases by elastase-specific inhibitors; J. Virol., 67 4688 4) Menendez-Arias et al. (1992), Isolation and characterization of alpha 2-macroglobulin-protease complexes from purified mouse mammary tumor virus and culture supernatants from virus-infected cell lines; J. Biol. Chem., 267 11392
ELASTATINAL Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | sales@alabiochem.com | China | 888 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29826 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 24607 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
DONBOO AMINO ACID COMPANY | +8613063595538 | donboo@donboo.com | China | 9365 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Alabiochem Tech.Co., Ltd. | 0512-58900862 400-0707518 | sales@alabiochem.com | China | 997 | 59 |
View Lastest Price from ELASTATINAL manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-01-09 | ELASTATINAL
51798-45-9
|
US $1.00 / g | 1g | ≥98% | g/kg/Ton | Career Henan Chemical Co |
- ELASTATINAL
51798-45-9
- US $1.00 / g
- ≥98%
- Career Henan Chemical Co