Sodium salicylate
- CAS No.
- 54-21-7
- Chemical Name:
- Sodium salicylate
- Synonyms
- SALICYLATE;NASAL;alysine;2-Hydroxybenzoate;clin;ardall;aroall;kerosal;nadisal;salisod
- CBNumber:
- CB1255762
- Molecular Formula:
- C7H5NaO3
- Molecular Weight:
- 160.1
- MDL Number:
- MFCD00002440
- MOL File:
- 54-21-7.mol
- MSDS File:
- SDS
| Melting point | >300 °C (lit.) |
|---|---|
| Density | 0.32 g/cm3 (20℃) |
| bulk density | 320kg/m3 |
| vapor pressure | <1 hPa ( 25 °C) |
| refractive index | 1.435 |
| storage temp. | Store at +15°C to +25°C. |
| solubility | 1000g/l |
| form | Crystals or Crystalline Powder |
| color | White |
| PH | 6.5 (100g/l, H2O, 20℃) |
| Odor | wh. lustrous cryst. scales or amorphous powd., odorless or faint odor, saline taste |
| Water Solubility | 1000 g/L (20 ºC) |
| Sensitive | Light Sensitive |
| Merck | 14,8332 |
| BRN | 3732792 |
| Stability | Stable. Incompatible with mineral acids, metallic salts, iodine. May be light-sensitive. |
| InChIKey | ABBQHOQBGMUPJH-UHFFFAOYSA-M |
| LogP | 2.061 (est) |
| CAS DataBase Reference | 54-21-7(CAS DataBase Reference) |
| Indirect Additives used in Food Contact Substances | SODIUM SALICYLATE |
| FDA 21 CFR | 175.105; 310.545 |
| EWG's Food Scores | 1 |
| FDA UNII | WIQ1H85SYP |
| NCI Dictionary of Cancer Terms | nasal; sodium salicylate |
| NCI Drug Dictionary | sodium salicylate |
| ATC code | N02BA04 |
| EPA Substance Registry System | Sodium salicylate (54-21-7) |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319-H361d | |||||||||
| Precautionary statements | P201-P202-P264-P301+P312-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-41-36/37/38-36 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | VO5075000 | |||||||||
| F | 8 | |||||||||
| Autoignition Temperature | >250 °C | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29182100 | |||||||||
| Toxicity | LD50 i.p. in rats: 780 mg/kg (Goldenthal) | |||||||||
| NFPA 704 |
|
Sodium salicylate price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3238 | Sodium Salicylate pharmaceutical secondary standard, certified reference material | 54-21-7 | 1G | $173 | 2024-03-01 | Buy |
| Sigma-Aldrich | 567630 | Sodium Salicylate - CAS 54-21-7 - Calbiochem A cell-permeable, non-steroidal anti-inflammatory agent that interferes with TNF-induced NF-κB activation by inhibiting phosphorylation and subsequent degradation of the IκB-α protein. | 54-21-7 | 5G | $56.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 31493 | Sodium salicylate puriss. p.a., Reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance) | 54-21-7 | 1kg | $208 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1.06601 | Sodium salicylate for analysis EMSURE? | 54-21-7 | 250g | $79.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1614636 | Sodium salicylate United States Pharmacopeia (USP) Reference Standard | 54-21-7 | 500mg | $420 | 2024-03-01 | Buy |
Sodium salicylate Chemical Properties,Uses,Production
Description
Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure. Historically, it has been synthesized from methyl salicylate (found in wintergreen plants or the bark of sweet birch tree) by reacting it with an excess of sodium hydroxide and heating it under reflux.
Chemical Properties
Sodium salicylate is of the salicylate family and this compound is known to trigger Reye's Syndrome in children and adults, usually following a viral infection such as influenza or chicken pox. Products containing such salicylates should not be given to children under the age of 19.
Chemical Properties
Sodium salicylate, HOC6H4COONa, is a shiny, white powder with sweetish taste and mild aromatic aroma that is soluble in water,glycerol, and alcohol.Used in medicine and as a preservative.
Uses
It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non - steroidal anti - inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. It is also a potential replacement for aspirin for people sensitive to it. It may also be used as a phosphor for the detection of vacuum ultra violet radiation and electrons.
Uses
keratolytic
Uses
In manufacture of aspirin, methyl salicylate, and other salicylates. Coupling agent for azo dyes. Has been used as food preservative.
Definition
A salt or ester of salicylic acid.
brand name
Alysine (Marion Merrell Dow).
General Description
Sodium salicylate may be prepared by the reaction, in aqueoussolution, by adding equal molar ratio of salicylic acidand sodium bicarbonate; evaporating to dryness yields thewhite salt. In solution, particularly in the presence of sodiumbicarbonate, the salt will darken on standing. This is the saltof choice for salicylate medication and usually is administeredwith sodium bicarbonate to lessen gastric distress, or itis administered in enteric coated tablets. However, the useof sodium bicarbonate is ill advised, because it decreases theplasma levels of salicylate and increases the excretion offree salicylate in the urine.
Sodium salicylate, even though not as potent as aspirinfor pain relief, also has less GI irritation and is useful for patientswho are hypersensitive to aspirin.
Biochem/physiol Actions
Cell permeable: yes
Safety Profile
Experimental poison by subcutaneous route. Moderately toxic to humans by ingestion. Moderately toxic experimentally by ingestion, intraperitoneal, and intravenous routes. An experimental teratogen. Human systemic effects by multiple and unspecified routes: toxic psychosis, excitement, respiratory stimulation, nausea or vomiting, and sweating. Experimental reproductive effects. Mutation data reported. A powerful irritant which affects the central nervous system. Incompatible with ferric salts, mineral acids, iodme, lead acetate, silver nitrate, sodium phosphate powder. When heated to decomposition it emits toxic fumes of Na2O.
Sodium salicylate Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6383 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12809 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5868 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18137 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3005 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20235 | 58 |
| airuikechemical co., ltd. | +86-18353166132 +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +86-17396673057 | linda@tnjone.com | China | 1143 | 58 |
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View Lastest Price from Sodium salicylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-25 | Sodium salicylate
54-21-7
|
US $0.00 / KG | 25KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-04-23 | Sodium salicylate
54-21-7
|
US $1.00 / kg | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-04-15 | Sodium salicylate
54-21-7
|
US $0.00-0.00 / kg | 1kg | 99.0% | 1tons | Henan Suikang Pharmaceutical Co.,Ltd. |
-
- Sodium salicylate
54-21-7
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Sodium salicylate
54-21-7
- US $1.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Sodium salicylate
54-21-7
- US $0.00-0.00 / kg
- 99.0%
- Henan Suikang Pharmaceutical Co.,Ltd.