ChemicalBook >> CAS DataBase List >>RETRORSINE
RETRORSINE
- CAS No.
- 480-54-6
- Chemical Name:
- RETRORSINE
- Synonyms
- RETRORSIN;Retrosine;RETRORSINE;Retrorcine;β-Longilobine;RETRORSINE(AS);BETA-LONGILOBINE;cis-retronecicacidesterofretronecine;16-dione,12,18-dihydroxy-senecionan-1;12,18-DIHYDROXYSENECIONAN-11,16-DIONE
- CBNumber:
- CB1256406
- Molecular Formula:
- C18H25NO6
- Molecular Weight:
- 351.39
- MDL Number:
- MFCD00870195
- MOL File:
- 480-54-6.mol
Last updated:2023-05-15 10:43:14
Melting point | 208-211 °C (lit.) |
---|---|
alpha | D18 -17.6° (c = 1.99 in ethanol) |
Boiling point | 485.2°C (rough estimate) |
Density | 1.32±0.1 g/cm3 (20 ºC 760 Torr) |
refractive index | 1.5100 (estimate) |
storage temp. | 2-8°C |
pka | 12.00±0.40(Predicted) |
Merck | 13,8253 |
InChIKey | BCJMNZRQJAVDLD-VMOBWIEOSA-N |
CAS DataBase Reference | 480-54-6 |
EWG's Food Scores | 1 |
FDA UNII | XJ86XWL8IY |
IARC | 3 (Vol. 10, Sup 7) 1987 |
EPA Substance Registry System | Retrorsine (480-54-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H300+H310+H330 |
Precautionary statements | P260-P262-P264-P280-P302+P352+P310-P304+P340+P310 |
Hazard Codes | T |
Risk Statements | 25 |
Safety Statements | 22-36/37/39-45 |
RIDADR | 1544 |
WGK Germany | 3 |
RTECS | VH7525000 |
HazardClass | 6.1(a) |
PackingGroup | II |
RETRORSINE price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | R0382 | Retrorsine ≥90% (HPLC) | 480-54-6 | 100mg | $261 | 2024-03-01 | Buy |
Sigma-Aldrich | R0382 | Retrorsine ≥90% (HPLC) | 480-54-6 | 500mg | $898 | 2024-03-01 | Buy |
Sigma-Aldrich | PHL89775 | Retrorsine phyproof Reference Substance | 480-54-6 | 10mg | $342 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | API0009902 | RETRORSINE 95.00% | 480-54-6 | 10MG | $573.3 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 48570 | Retrorsine | 480-54-6 | 10mg | $585 | 2021-12-16 | Buy |
RETRORSINE Chemical Properties,Uses,Production
Uses
Retrorsine-D4 is a labelled analogue of Retrorsine (R279000). Retrorsine is a pyrrolizidine alkaloid that blocks the hepatocyte cell cycle, ultimately affecting hepatocyte proliferative capacity.
Definition
ChEBI: Retrorsine is a macrolide.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Safety Profile
Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. hhtation data reported. When heated to decomposition it emits toxic fumes of NOx.
![69102-07-4](/CAS/GIF/69102-07-4.gif)
![102731-60-2](/CAS/20210305/GIF/1000210-73-0.gif)
![480-54-6](/CAS/GIF/480-54-6.gif)
Synthesis of RETRORSINE from PUTRESCINE-1,4-14C DIHYDROCHLORIDE and Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-
RETRORSINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 90)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chengdu Greenpure Biopharma CO.,Ltd | +8618283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9626 | 58 |
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9020 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
480-54-6(RETRORSINE)Related Search:
ALLYL ISOVALERATE
3-METHOXYPYRROLIDINE
(2-Propenyloxy)propanol
Butyl hydroxyacetate
3-ALLYLOXY-1,2-PROPANEDIOL
2-Dimethylaminoethyl acetate
DIMETHYL 2-METHYLADIPATE
3-Butoxypropanamine
2-HYDROXY-3-METHYLBUTYRIC ACID
3-Pyrrolidinol
1of4
BETA-LONGILOBINE
12,18-DIHYDROXYSENECIONAN-11,16-DIONE
RETRORSINE
16-dione,12,18-dihydroxy-senecionan-1
5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-hydroxymethyl-5-3-ethylidene-4
cis-retronecicacidesterofretronecine
methyl(1,6)dioxacyclododeca(2,3,4-gh)pyrrolizidine-2,7-dione
trans-15-ethylidene-12beta-hydroxy-12alpha-hydroxymethyl-13beta-methylsenec-1-
RETRORSINE(AS)
β-Longilobine, 12,18-Dihydroxysenecionan-11,16-dione
β-Longilobine
Retrorcine
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-, (3Z,5R,6S,14aR,14bR)-
RETRORSIN
Retrosine
480-54-6
C18H23O5N