- Retrorsine
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- $35.00 / 1mg
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2024-10-30
- CAS:480-54-6
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | RETRORSINE Basic information |
| Product Name: | RETRORSINE | | Synonyms: | BETA-LONGILOBINE;12,18-DIHYDROXYSENECIONAN-11,16-DIONE;RETRORSINE;16-dione,12,18-dihydroxy-senecionan-1;5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-hydroxymethyl-5-3-ethylidene-4;cis-retronecicacidesterofretronecine;methyl(1,6)dioxacyclododeca(2,3,4-gh)pyrrolizidine-2,7-dione;trans-15-ethylidene-12beta-hydroxy-12alpha-hydroxymethyl-13beta-methylsenec-1- | | CAS: | 480-54-6 | | MF: | C18H25NO6 | | MW: | 351.39 | | EINECS: | 610-403-9 | | Product Categories: | | | Mol File: | 480-54-6.mol |  |
| | RETRORSINE Chemical Properties |
| Melting point | 208-211 °C (lit.) | | alpha | D18 -17.6° (c = 1.99 in ethanol) | | Boiling point | 485.2°C (rough estimate) | | density | 1.32±0.1 g/cm3 (20 ºC 760 Torr) | | refractive index | 1.5100 (estimate) | | storage temp. | 2-8°C | | form | Solid | | pka | 12.00±0.40(Predicted) | | color | White to off-white | | Merck | 13,8253 | | InChIKey | BCJMNZRQJAVDLD-VMOBWIEOSA-N | | CAS DataBase Reference | 480-54-6 | | IARC | 3 (Vol. 10, Sup 7) 1987 | | EPA Substance Registry System | Retrorsine (480-54-6) |
| | RETRORSINE Usage And Synthesis |
| Uses | Retrorsine-D4 is a labelled analogue of Retrorsine (R279000). Retrorsine is a pyrrolizidine alkaloid that blocks the hepatocyte cell cycle, ultimately affecting hepatocyte proliferative capacity. | | Definition | ChEBI: Retrorsine is a macrolide. | | General Description | This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG | | Safety Profile | Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. hhtation data reported. When heated to decomposition it emits toxic fumes of NOx. |
| | RETRORSINE Preparation Products And Raw materials |
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