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CAY10614

CAY10614 Structure
CAY10614 structure
CAS No.
1202208-36-3
Chemical Name:
CAY10614
Synonyms
CAY10614;CAY10614 Exclusive;cyclopentyl-[[3,4-di(tetradecoxy)phenyl]methyl]-dimethylazanium:iodide;N-cyclopentyl-N,N-dimethyl-3,4-bis(tetradecyloxy)-benzenemethanaminium, iodide
CBNumber:
CB12590443
Molecular Formula:
C42H78INO2
Molecular Weight:
756
MDL Number:
MFCD18382116
MOL File:
1202208-36-3.mol
Last updated:2024-07-02 08:55:00
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CAY10614 Properties

storage temp. Store at -20°C
solubility DMF: 0.15 mg/ml; DMSO: 0.14 mg/ml
form A crystalline solid
color White to off-white

CAY10614 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13615 CAY10614 ≥98% 1202208-36-3 1mg $55 2024-03-01 Buy
Cayman Chemical 13615 CAY10614 ≥98% 1202208-36-3 5mg $236 2024-03-01 Buy
Cayman Chemical 13615 CAY10614 ≥98% 1202208-36-3 10mg $420 2024-03-01 Buy
Cayman Chemical 13615 CAY10614 ≥98% 1202208-36-3 25mg $914 2024-03-01 Buy
AK Scientific 1922AH N-Cyclopentyl-N,N-dimethyl-3,4-bis(tetradecyloxy)-benzenemethanaminium,iodide 1202208-36-3 1mg $158 2021-12-16 Buy
Product number Packaging Price Buy
13615 1mg $55 Buy
13615 5mg $236 Buy
13615 10mg $420 Buy
13615 25mg $914 Buy
1922AH 1mg $158 Buy

CAY10614 Chemical Properties,Uses,Production

Description

Lipid A is a lipid-rich component of endotoxin, also known as lipopolysaccharide (LPS), which in turn is part of the outer membrane of Gram-negative bacteria. Lipid A activates toll-like receptor 4 (TLR4), initiating an immune response. CAY10614 is an antagonist of lipid A activation of TLR4, exhibiting an IC50 value of 1.68 μM in a cell-based assay using modified human embryonic kidney (HEK) cells.1 It does not significantly affect HEK cell viability. In a model of sepsis, CAY10614 dramatically and significantly improves survival of mice given intraperitoneal LPS.1

References

1. Piazza, M., Rossini, C., Fiorentina, S.D., et al. Glycolipids and benzylammonium lipids as novel antisepsis agents: Synthesis and biological characterization J. Med. Chem. 52(4),1209-1213(2009).

CAY10614 Preparation Products And Raw materials

Raw materials

Preparation Products

CAY10614 Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Xingui Biotechnology Co., Ltd. 17501653715 xingui2022@126.com China 10033 58
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29795 68
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9294 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28118 58
Supplier Advantage
Shanghai Xingui Biotechnology Co., Ltd. 58
BOC Sciences 65
Shanghai EFE Biological Technology Co., Ltd. 58
Beijing Solarbio Science & Tecnology Co., Ltd. 68
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
RD International Technology Co., Limited 58
TargetMol Chemicals Inc. 58
CAY10614 N-cyclopentyl-N,N-dimethyl-3,4-bis(tetradecyloxy)-benzenemethanaminium, iodide CAY10614 Exclusive cyclopentyl-[[3,4-di(tetradecoxy)phenyl]methyl]-dimethylazanium:iodide 1202208-36-3