(+)-Blebbistatin
- CAS No.
- 1177356-70-5
- Chemical Name:
- (+)-Blebbistatin
- Synonyms
- (+)Blebbistatin,(+) Blebbistatin;(+)-Blebbistatin - CAS 1177356-70-5 - Calbiochem;4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aR)-
- CBNumber:
- CB12620724
- Molecular Formula:
- C18H16N2O2
- Molecular Weight:
- 292.33
- MDL Number:
- MFCD08460906
- MOL File:
- 1177356-70-5.mol
- MSDS File:
- SDS
| Boiling point | 507.3±60.0 °C(Predicted) |
|---|---|
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | -20C |
| solubility | DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 12.5 mg/ml |
| form | Yellow solid |
| pka | 11.15±0.20(Predicted) |
| FDA UNII | XWG1958E8I |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H317 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P272-P280-P301+P312-P330-P302+P352-P304+P340-P305+P351+P338-P362+P364-P333+P313-P321-P337+P313-P363-P501 | |||||||||
| NFPA 704 |
|
(+)-Blebbistatin price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 203392 | (+)-Blebbistatin - CAS 1177356-70-5 - Calbiochem The inactive enantiomer of (±)-Blebbistatin. | 1177356-70-5 | 1mg | $172 | 2024-03-01 | Buy |
| Cayman Chemical | 13165 | (+)-Blebbistatin ≥98% | 1177356-70-5 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 13165 | (+)-Blebbistatin ≥98% | 1177356-70-5 | 5mg | $151 | 2024-03-01 | Buy |
| Cayman Chemical | 13165 | (+)-Blebbistatin ≥98% | 1177356-70-5 | 10mg | $283 | 2024-03-01 | Buy |
| Cayman Chemical | 13165 | (+)-Blebbistatin ≥98% | 1177356-70-5 | 25mg | $618 | 2024-03-01 | Buy |
(+)-Blebbistatin Chemical Properties,Uses,Production
Chemical Properties
Bright Yellow Solid
Uses
Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. It blocks both blebbing and cytokinesis at 50-100μM. A negative control for the (S)-(-)-Blebblastatin. [a]D= +110 (c= 1.21 CHCl3) (±)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-one Selective inhibitor of nonmuscle myosin II; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells.
Definition
ChEBI: (R)-blebbistatin is the (R)-enantiomer of blebbistatin. It is a blebbistatin and a tertiary alpha-hydroxy ketone.
storage
Store at +4°C
(+)-Blebbistatin Preparation Products And Raw materials
Raw materials
Preparation Products
(+)-Blebbistatin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4694 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4264 | 55 | |
| Guangzhou Zhiya Chemdrugs Co.,Ltd | 18122150900 | sculk28@163.com | China | 646 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |