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CNX-1351

CAS No.
1276105-89-5
Chemical Name:
CNX-1351
Synonyms
CS-1069;CNX-1351;CNX1351cas;CNX-1351, >=98%;CNX-1351; CNX 1351; CNX1351;CNX1351,inhibit,PI3K,Phosphoinositide 3-kinase,Inhibitor,CNX 1351,CNX-1351;1-(4-((2-(1H-indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-6-methylhept-5-ene-1,4-dione;1-[4-[[2-(1H-Indazol-4-yl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]-1-piperazinyl]-6-methyl-5-heptene-1,4-dione;5-Heptene-1,4-dione, 1-[4-[[2-(1H-indazol-4-yl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]-1-piperazinyl]-6-methyl-;1-[4-[[2-(1H-Indazol-4-yl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]-1-piperazinyl]-6-methyl-5-heptene-1,4-dione CNX1351
CBNumber:
CB12668207
Molecular Formula:
C30H35N7O3S
Molecular Weight:
573.71
MDL Number:
MFCD25976872
MOL File:
1276105-89-5.mol
MSDS File:
SDS
Last updated:2024-11-19 20:33:22

CNX-1351 Properties

Density 1.328±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 33.33 mg/mL (58.10 mM; Need ultrasonic)
form Powder
pka 12.22±0.40(Predicted)
color White to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

CNX-1351 price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30264 CNX-1351 1276105-89-5 5mg $116 2024-03-01 Buy
Cayman Chemical 30264 CNX-1351 1276105-89-5 25mg $442 2024-03-01 Buy
Cayman Chemical 30264 CNX-1351 1276105-89-5 1mg $37 2024-03-01 Buy
Cayman Chemical 30264 CNX-1351 1276105-89-5 10mg $213 2024-03-01 Buy
ChemScene CS-3610 CNX-1351 99.88% 1276105-89-5 10mg $240 2021-12-16 Buy
Product number Packaging Price Buy
30264 5mg $116 Buy
30264 25mg $442 Buy
30264 1mg $37 Buy
30264 10mg $213 Buy
CS-3610 10mg $240 Buy

CNX-1351 Chemical Properties,Uses,Production

Biological Activity

CNX-1351 is a potent and selective PI3Kα inhibitor with IC50 of 6.8 nM.

in vivo

CNX-1351 inhibits p-Akt Ser473 in mouse spleens and bonds to PI3Kα in vivo. It is delivered into the intraperitoneal cavity of nude mice at 100 mg/kg once a day for 5 consecutive days (n=3 mice per group).

target

PI3Kα

6.8 nM (IC 50 )

PI3Kβ

166 nM (IC 50 )

PI3Kδ

240.3 nM (IC 50 )

PI3Kγ

3020 nM ( IC 50 )

CNX-1351 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24727 58
Chemtour Biotech Co., Ltd
+8617327281506 market@chemtour.com China 1460 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8467 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2922 55
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7552 61

View Lastest Price from CNX-1351 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CNX-1351 pictures 2024-11-19 CNX-1351
1276105-89-5
US $41.00-155.00 / mg 99.69% 10g TargetMol Chemicals Inc.
  • CNX-1351 pictures
  • CNX-1351
    1276105-89-5
  • US $41.00-155.00 / mg
  • 99.69%
  • TargetMol Chemicals Inc.
1-[4-[[2-(1H-Indazol-4-yl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]-1-piperazinyl]-6-methyl-5-heptene-1,4-dione CNX1351 CNX-1351, >=98% CNX-1351 1-[4-[[2-(1H-Indazol-4-yl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]-1-piperazinyl]-6-methyl-5-heptene-1,4-dione 1-(4-((2-(1H-indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-6-methylhept-5-ene-1,4-dione CS-1069 CNX-1351; CNX 1351; CNX1351 CNX1351cas CNX1351,inhibit,PI3K,Phosphoinositide 3-kinase,Inhibitor,CNX 1351,CNX-1351 5-Heptene-1,4-dione, 1-[4-[[2-(1H-indazol-4-yl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]-1-piperazinyl]-6-methyl- 1276105-89-5 C30H35N7O3S Inhibitors