alisporivir
- CAS No.
- 254435-95-5
- Chemical Name:
- alisporivir
- Synonyms
- DEB-025;Debio-025;alisporivir;Alisporivir (Debio-025);alisporivir /DB025/DB-025;Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-D-alanyl-N-ethyl-L-valyl-L-valyl-N-methyl-L-leucyl]
- CBNumber:
- CB12677410
- Molecular Formula:
- C63H113N11O12
- Molecular Weight:
- 1216.66
- MDL Number:
- MFCD32694261
- MOL File:
- 254435-95-5.mol
| Boiling point | 1294.2±65.0 °C(Predicted) |
|---|---|
| Density | 1.011±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : ≥ 100 mg/mL (82.19 mM) |
| pka | 13.32±0.70(Predicted) |
| form | Solid |
| color | White to off-white |
| FDA UNII | VBP9099AA6 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H372-H361-H302-H413 |
| Precautionary statements | P260-P264-P270-P314-P501-P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501 |
alisporivir Chemical Properties,Uses,Production
Uses
Trofinetide is a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), that has shown to be neuroprotective in animal models of brain injury.
Definition
ChEBI: Alisporivir is a homodetic cyclic peptide. It has a role as an anticoronaviral agent.
Biological Activity
Alisporivir is a Cyclophilin A inhibitor with potent anti-hepatitis C virus (HCV) activity. Alisporivir has also been investigated for Duchenne muscular dystrophy.
in vivo
Combination treatment with Alisporivir and ICN-1229 does not protect against SARS-CoV infection in a mouse model[3].
alisporivir Preparation Products And Raw materials
Raw materials
Preparation Products
alisporivir Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| Guangzhou Biocar Biotechnology Co.,Ltd. | +86-13397196830 | carrie@gzbiocar.cn | China | 435 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3466 | 58 |
| Shanghai Chaolan Chemical Technology Center | 021-QQ：65489617 15618227136 | Sales@ATKchemical.com | China | 9330 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
| Heze Development Zone chuangli Chemical Co., Ltd. | 0530-+86-530-529 6766，+86-15666160102 15666160102 | info@chuangli-chem.com | China | 838 | 55 |