4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid

4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid structure

CAS No.: 27031-00-1

Chemical Name:: 4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid

Synonyms: iGP-1;4-[[4-(2-Benzimidazolyl)phenyl]amino]-4-oxobutanoic Acid;4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-oxobutanoic acid;4-{[4-(1H-benzimidazol-2-yl)phenyl]amino}-4-oxobutanoic acid;4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-oxo-butanoic acid;4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid;Butanoic acid, 4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-oxo-;4-((4-(1H-Benzo[d]imidazol-2-yl)phenyl)amino)-4-oxobutanoic acid

CBNumber:: CB13055936

Molecular Formula:: C17H15N3O3

Molecular Weight:: 309.32

MDL Number:: MFCD00395378

MOL File:: 27031-00-1.mol

Last updated:2023-07-18 08:29:06

Request For Quotation

4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid Properties

Density	1.398±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO (up to 50 mg/ml).
form	solid
pka	4.48±0.10(Predicted)
color	Beige
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	159611	4-{[4-(1H-Benzimidazol-2-yl)phenyl]amino}-4-oxobutanoic acid	27031-00-1	0.500g	$120	2021-12-16	Buy
Matrix Scientific	159611	4-{[4-(1H-Benzimidazol-2-yl)phenyl]amino}-4-oxobutanoic acid	27031-00-1	1g	$150	2021-12-16	Buy

Product number	Packaging	Price	Buy
159611	0.500g	$120	Buy
159611	1g	$150	Buy

4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid Chemical Properties,Uses,Production

Description

iGP-1 (27031-00-1) is a potent and cell permeable inhibitor of mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), IC50=6.3 μM, that is selective over the cytosolic enzyme1. It does not block pyruvate uptake into cells or mitochondria and has no direct effect on glycolysis in synaptosomes. This novel inhibitor is a unique tool which may be used to investigate the role of glycerol-3-phosphate metabolism in isolated and intact systems.1

References

1) Orr?et al.?(2014),?Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase; PLoS One,?9?e89938

4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid synthesis

Synthesis of 4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid from Succinic anhydride and 4-(1H-BENZOIMIDAZOL-2-YL)-PHENYLAMINE

4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid Suppliers

Global( 18)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11012	58
MQ (shanghai) Pharmaceuticals Co., Ltd.	13761635123	1014988033@qq.com	China	4997	55
Shanghai Puhao Chemical Technology Co. Ltd.	13761817188	774028079@qq.com	China	283	58
Zhengzhou anmousse chemical products co. LTD	0371-55289822 18737195735	483339295@qq.com	China	7097	58
Zhengzhou Convergence Chemical Co. LTD	0371-53736046 13393710386	2853979814@qq.com	China	9987	58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.	021-51816796-820 13611835272	sales2@sunwaypharm.com	China	44484	58
Bide Pharmatech Ltd.	400-1647117 15221909166	product02@bidepharm.com	China	63720	58
Ningbo Chemrio Chemtech Co,.Ltd.	0574-27891269 18667892864	frank.xiaodong@chemriotech.com	China	3583	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
MQ (shanghai) Pharmaceuticals Co., Ltd.	55
Shanghai Puhao Chemical Technology Co. Ltd.	58
Zhengzhou anmousse chemical products co. LTD	58
Zhengzhou Convergence Chemical Co. LTD	58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.	58
Bide Pharmatech Ltd.	58
Ningbo Chemrio Chemtech Co,.Ltd.	58
TargetMol Chemicals Inc.	58

27031-00-1(4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid)Related Search:

5-[(2R)-2-([(2R)-2-(3-CHLOROPHENYL)-2-HYDROXYETHYL]AMINO)PROPYL]-1,3-BENZODIOXOLE-2,2-DICARBOXYLATE DISODIUM PUROMYCIN DIHYDROCHLORIDE TYRPHOSTIN A9 Vanillylidenacetone

4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid 4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-oxobutanoic acid 4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-oxo-butanoic acid 4-{[4-(1H-benzimidazol-2-yl)phenyl]amino}-4-oxobutanoic acid 4-((4-(1H-Benzo[d]imidazol-2-yl)phenyl)amino)-4-oxobutanoic acid iGP-1 Butanoic acid, 4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-oxo- 4-[[4-(2-Benzimidazolyl)phenyl]amino]-4-oxobutanoic Acid 27031-00-1