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ChemicalBook >> CAS DataBase List >>N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine

N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine

N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine Structure
N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine structure
CAS No.
1252927-45-9
Chemical Name:
N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine
Synonyms
Parahappani impurity 50;N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine;2H-Indazol-6-amine, N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-;(4-Chloro-pyrimidin-2-yl)-(2,3-dimethyl-2H-indazol-6-yl)-methyl-amine
CBNumber:
CB13106775
Molecular Formula:
C14H14ClN5
Molecular Weight:
287.75
MDL Number:
MFCD18917547
MOL File:
1252927-45-9.mol
Last updated:2023-06-06 08:28:35
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N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine Properties

Boiling point 497.8±53.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
pka 2.96±0.30(Predicted)

N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine Chemical Properties,Uses,Production

Uses

N-(4-Chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine is an intermediate in the synthesis of 5-((2-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-4-yl)amino)-2-methylbenzenesulfonamide Hydrochloride (D474433) which is an impurity of Pazopanib (P210925), which is an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine synthesis

1226499-97-3
74-88-4
1252927-45-9
Synthesis of N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine from N-(4-chloro-2-pyrimidinyl)-2,3-dimethyl-2H-Indazol-6-amine and Iodomethane

N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine Preparation Products And Raw materials

Raw materials

2,3-dimethyl-2H-indazol-6-amine hydrochloride N-(4-chloro-2-pyrimidinyl)-2,3-dimethyl-2H-Indazol-6-amine Iodomethane

Preparation Products

N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7182 65
Shenzhen ruikai de biotechnology co., ltd. 0755-61348847 17820674378 2682116078@qq.com China 7844 58
Hubei Xinyang Medical Technology Co., Ltd 15347293736 15347293736 2853117764@qq.com China 7888 58
Molcoo Chemicals Inc. 18627923403 18627753421 3001006472@qq.com China 9284 58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd 18502726233; 18502726233 3641133981@qq.com China 9808 58
Supplier Advantage
China National Standard Pharmaceutical Corporation Limited 		58
Daicel Chiral Technologies (China)CO.,LTD 65
Shenzhen ruikai de biotechnology co., ltd. 58
Hubei Xinyang Medical Technology Co., Ltd 58
Molcoo Chemicals Inc. 58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd 58
N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine (4-Chloro-pyrimidin-2-yl)-(2,3-dimethyl-2H-indazol-6-yl)-methyl-amine 2H-Indazol-6-amine, N-(4-chloro-2-pyrimidinyl)-N,2,3-trimethyl- Parahappani impurity 50 1252927-45-9