ChemicalBook >> CAS DataBase List >>ARS-1620

ARS-1620

CAS No.
1698055-85-4
Chemical Name:
ARS-1620
Synonyms
CPD1588;ARS-1620;ARS-1620;ARS 1620;ARS1620;inhibit,Ras,Inhibitor,ARS-1620,ARS 1620,ARS1620;(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one;(S)-1-[4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-2-propen-1-one;2-Propen-1-one, 1-[4-[(7S)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-;1-?[4-?[(7S)?-?6-?Chloro-?8-?fluoro-?7-?(2-?fluoro-?6-?hydroxyphenyl)?-?4-?quinazolinyl]?-?1-?piperazinyl]?-?2-?propen-?1-?one
CBNumber:
CB13369787
Molecular Formula:
C21H17ClF2N4O2
Molecular Weight:
430.84
MDL Number:
MFCD31619312
MOL File:
1698055-85-4.mol
Last updated:2024-11-19 23:02:33

ARS-1620 Properties

Boiling point 614.7±55.0 °C(Predicted)
Density 1.434±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:70.0(Max Conc. mg/mL);162.47(Max Conc. mM)
form A solid
pka 6.03±0.35(Predicted)
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

ARS-1620 price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27915 ARS1620 1698055-85-4 1mg $118 2024-03-01 Buy
Cayman Chemical 27915 ARS1620 1698055-85-4 5mg $351 2024-03-01 Buy
ChemScene CS-0035119 ARS-1620 99.20% 1698055-85-4 25mg $690 2021-12-16 Buy
ChemScene CS-0035119 ARS-1620 99.20% 1698055-85-4 50mg $990 2021-12-16 Buy
ChemScene CS-0035119 ARS-1620 99.20% 1698055-85-4 100mg $1250 2021-12-16 Buy
Product number Packaging Price Buy
27915 1mg $118 Buy
27915 5mg $351 Buy
CS-0035119 25mg $690 Buy
CS-0035119 50mg $990 Buy
CS-0035119 100mg $1250 Buy

ARS-1620 Chemical Properties,Uses,Production

Uses

ARS-1620, is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.

Definition

ChEBI: ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent.

ARS-1620 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 81)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32956 60
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29810 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9639 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58

View Lastest Price from ARS-1620 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ARS-1620 pictures 2024-11-19 ARS-1620
1698055-85-4
US $84.00-198.00 / mg ≥95% 10g TargetMol Chemicals Inc.
ARS-1620 pictures 2020-01-19 ARS-1620
1698055-85-4
US $1.00 / KG 1KG 99.0% 100kg Career Henan Chemical Co
  • ARS-1620 pictures
  • ARS-1620
    1698055-85-4
  • US $84.00-198.00 / mg
  • ≥95%
  • TargetMol Chemicals Inc.
  • ARS-1620 pictures
  • ARS-1620
    1698055-85-4
  • US $1.00 / KG
  • 99.0%
  • Career Henan Chemical Co

1698055-85-4(ARS-1620)Related Search:

ARS-1620 CPD1588 ARS-1620;ARS 1620;ARS1620 (S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one 1-?[4-?[(7S)?-?6-?Chloro-?8-?fluoro-?7-?(2-?fluoro-?6-?hydroxyphenyl)?-?4-?quinazolinyl]?-?1-?piperazinyl]?-?2-?propen-?1-?one 2-Propen-1-one, 1-[4-[(7S)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]- (S)-1-[4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-2-propen-1-one inhibit,Ras,Inhibitor,ARS-1620,ARS 1620,ARS1620 1698055-85-4 C21H17ClF2N4O2 APIs API