ChemicalBook >> CAS DataBase List >>DFMO
DFMO
- CAS No.
- 66640-93-5
- Chemical Name:
- DFMO
- Synonyms
- DFMO;L-DFMO;L-RMI71782;EFLORNITINE;L-Eflornithine;H-DL-(F2ME)ORN-OH;DIFLUOROMETHYLORNITHINE;L-α-difluoromethylornithine;L-α-difluoromethylornithine;L Eflornithine,LEflornithine
- CBNumber:
- CB1373228
- Molecular Formula:
- C6H12F2N2O2
- Molecular Weight:
- 182.17
- MDL Number:
- MFCD00221766
- MOL File:
- 66640-93-5.mol
Last updated:2024-10-28 23:16:16
Boiling point | 347.0±42.0 °C(Predicted) |
---|---|
Density | 1.293±0.06 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
pka | 1.22±0.44(Predicted) |
NCI Dictionary of Cancer Terms | difluoromethylornithine |
FDA UNII | C780YUS9YI |
DFMO Chemical Properties,Uses,Production
Biological Activity
L-Eflornithine (L-DFMO) is the enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with KD of 1.3±0.3 μM and Kinact of 0.15±0.03 min-1.
in vivo
The more potent L-Eflornithine is present at much lower concentrations in both plasma and cerebrospinal fluid (CSF) than those of the D-Eflornithine. The plasma concentrations of L-Eflornithine are on average 52% of the D -enantiomer concentrations. The typical oral clearances of L-Eflornithine and D-eflornithine are 17.4 and 8.23 liters/h, respectively.
target
KD: 1.3±0.3 μM (Ornithine decarboxylase, ODC)
DFMO Preparation Products And Raw materials
Raw materials
Preparation Products
DFMO Suppliers
Global( 14)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32063 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38463 | 58 | |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52925 | 58 |
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19863 | 58 |
Sanover (Xiamen) Technology Co., Ltd | 059265188632; 13876246362 | 422165847@qq.com | China | 509 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24648 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
Aladdin Scientific | 58 |
TargetMol Chemicals Inc. | 58 |
Sanover (Xiamen) Technology Co., Ltd | 58 |
TargetMol Chemicals Inc. | 58 |
View Lastest Price from DFMO manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-28 | L-Eflornithine
66640-93-5
|
US $1520.00-1980.00 / mg | 10g | TargetMol Chemicals Inc. |
- L-Eflornithine
66640-93-5
- US $1520.00-1980.00 / mg
- TargetMol Chemicals Inc.
66640-93-5(DFMO)Related Search:
ALPHA-DIFLUORO-ME-DL-ORNITHINE
ALPHA-DIFLUOROMETHYL-DL-ORNITHINE
L-alpha-Difluoromethylornithine
DFMO
EFLORNITINE
DL-ALPHA-DIFLUOROMETHYLORNITHINE
DIFLUOROMETHYLORNITHINE
H-DL-(F2ME)ORN-OH
H-DL-(ALPHA-DIFLUOROMETHYL)ORN-OH
H-ALPHA-DIFLUORO-ME-DL-ORN-OH
L-Eflornithine
L-α-difluoromethylornithine
L-Ornithine, 2-(difluoromethyl)-
L-α-difluoromethylornithine
L-RMI71782
L-DFMO
L Eflornithine,LEflornithine
66640-93-5
Angiogenesis
BioChemical
Cancer Research
Angiogenesis Inhibitors