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DFMO

DFMO structure

CAS No.: 66640-93-5

Chemical Name:: DFMO

Synonyms: DFMO;L-DFMO;L-RMI71782;EFLORNITINE;L-Eflornithine;H-DL-(F2ME)ORN-OH;DIFLUOROMETHYLORNITHINE;L-α-difluoromethylornithine;L-α-difluoromethylornithine;L Eflornithine,LEflornithine

CBNumber:: CB1373228

Molecular Formula:: C6H12F2N2O2

Molecular Weight:: 182.17

MDL Number:: MFCD00221766

MOL File:: 66640-93-5.mol

Last updated:2024-10-28 23:16:16

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DFMO Properties

Boiling point	347.0±42.0 °C(Predicted)
Density	1.293±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
pka	1.22±0.44(Predicted)
NCI Dictionary of Cancer Terms	difluoromethylornithine
FDA UNII	C780YUS9YI

DFMO price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AHH	MT-50140	Difluoromethylornithine 98%	66640-93-5	1g	$310	2021-12-16	Buy

Product number	Packaging	Price	Buy
MT-50140	1g	$310	Buy

DFMO Chemical Properties,Uses,Production

Biological Activity

L-Eflornithine (L-DFMO) is the enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with KD of 1.3±0.3 μM and Kinact of 0.15±0.03 min-1.

in vivo

The more potent L-Eflornithine is present at much lower concentrations in both plasma and cerebrospinal fluid (CSF) than those of the D-Eflornithine. The plasma concentrations of L-Eflornithine are on average 52% of the D -enantiomer concentrations. The typical oral clearances of L-Eflornithine and D-eflornithine are 17.4 and 8.23 liters/h, respectively.

target

KD: 1.3±0.3 μM (Ornithine decarboxylase, ODC)

DFMO Preparation Products And Raw materials

Raw materials

Preparation Products

DFMO Suppliers

Global( 14)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
TargetMol Chemicals Inc.	+8613564774135	zijue.cai@tsbiochem.com	United States	19885	58
Sanover (Xiamen) Technology Co., Ltd	059265188632; 13876246362	422165847@qq.com	China	508	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24644	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
TargetMol Chemicals Inc.	58
Sanover (Xiamen) Technology Co., Ltd	58
TargetMol Chemicals Inc.	58

View Lastest Price from DFMO manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-28	L-Eflornithine 66640-93-5	US $1520.00-1980.00 / mg			10g	TargetMol Chemicals Inc.

L-Eflornithine
66640-93-5
US $1520.00-1980.00 / mg
TargetMol Chemicals Inc.

66640-93-5(DFMO)Related Search:

BETA-FLUORO-DL-ALANINE 2-(TRIFLUOROMETHYL)ORNITHINE DFMO Eflornithine hydrochloride DFMO

ALPHA-DIFLUORO-ME-DL-ORNITHINE ALPHA-DIFLUOROMETHYL-DL-ORNITHINE L-alpha-Difluoromethylornithine DFMO EFLORNITINE DL-ALPHA-DIFLUOROMETHYLORNITHINE DIFLUOROMETHYLORNITHINE H-DL-(F2ME)ORN-OH H-DL-(ALPHA-DIFLUOROMETHYL)ORN-OH H-ALPHA-DIFLUORO-ME-DL-ORN-OH L-Eflornithine L-α-difluoromethylornithine L-Ornithine, 2-(difluoromethyl)- L-α-difluoromethylornithine L-RMI71782 L-DFMO L Eflornithine,LEflornithine 66640-93-5 Angiogenesis BioChemical Cancer Research Angiogenesis Inhibitors