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1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one structure

CAS No.: 55314-16-4

Chemical Name:: 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one

Synonyms: 4G-951;Imatinib Impurity 19;Imatinib Impurity 74;Imatinib EP Impurity A;Imatinib USP Impurity A;Nilotinib??Intermediates?B;Imatinib Related Compound A;Imatinib Dimethylamino Impurity;3-Dimethylamino-1-pyridin-3-yl-pr;3-[3-(Dimethylamino)acryloyl]pyridine

CBNumber:: CB1406106

Molecular Formula:: C10H12N2O

Molecular Weight:: 176.22

MDL Number:: MFCD00115180

MOL File:: 55314-16-4.mol

Last updated:2025-01-27 09:38:02

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1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Properties

Melting point	86-88
Boiling point	281.4±36.0 °C(Predicted)
Density	1.070±0.06 g/cm3(Predicted)
vapor pressure	0.049Pa at 20℃
storage temp.	Inert atmosphere,Room Temperature
solubility	Soluble in chloroform and dichloromethane.
form	powder to crystal
pka	6.19±0.70(Predicted)
color	Light yellow to Brown
InChI	InChI=1S/C10H12N2O/c1-12(2)7-5-10(13)9-4-3-6-11-8-9/h3-8H,1-2H3
InChIKey	MZLRFUCMBQWLNV-FNORWQNLSA-N
SMILES	C(C1=CC=CN=C1)(=O)C=CN(C)C
LogP	0.26 at 20℃ and pH7.2
Surface tension	71.8mN/m at 1.008g/L and 20℃
CAS DataBase Reference	55314-16-4(CAS DataBase Reference)
FDA UNII	MD6L0C82BN
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Xi,Xn

Risk Statements

22-36/37/38

Safety Statements

26-36/37/39

HazardClass

IRRITANT

HS Code

29333990

NFPA 704

	1
2		0

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	D3949	2-(Dimethylamino)vinyl 3-Pyridyl Ketone >98.0%(GC)	55314-16-4	1g	$68	2023-06-20	Buy
TCI Chemical	D3949	2-(Dimethylamino)vinyl 3-Pyridyl Ketone >98.0%(GC)	55314-16-4	5g	$204	2023-06-20	Buy
Alfa Aesar	H54187	3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, 97%	55314-16-4	5g	$208	2021-12-16	Buy
Alfa Aesar	H54187	3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, 97%	55314-16-4	1g	$53.2	2021-12-16	Buy
Alfa Aesar	H54187	3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, 97%	55314-16-4	250mg	$17.8	2021-12-16	Buy

Product number	Packaging	Price	Buy
D3949	1g	$68	Buy
D3949	5g	$204	Buy
H54187	5g	$208	Buy
H54187	1g	$53.2	Buy
H54187	250mg	$17.8	Buy

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Chemical Properties,Uses,Production

Description

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one can be used in the synthesis of imatinib and nilotinib (AMN107), a compound currently in multiple Phase II/III clinical trials for chronic granulocytic leukaemia. Imatinib, on the other hand, is a cancer growth blocker known as a tyrosine kinase inhibitor (TKI), which is used to treat a wide range of leukaemias, myelodysplastic/myeloproliferative disorders, systemic mastocytosis, eosinophilia syndromes, raised dermal fibrosarcoma and gastrointestinal mesenchymal tumours.

Chemical Properties

Off-White Solid

Uses

3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one is used ads pharmaceutical intermediate, an imatinib intermediate.

Uses

Rasagiline intermediate

Solubility in organics

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one is soluble in Chloroform and Dichloromethane.

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide N,N-Dimethylformamide dimethyl acetal 3-Acetylpyridine

Preparation Products

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one Suppliers

Global( 259)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Yangzhou Qinyuan Pharmatech Co.,ltd	+86-18752526868	jennysun@yzqyyykj.com	China	81	58
QUALITY CONTROL SOLUTIONS LTD.	0755-66853366; 13670046396	ORDERS@QCSRM.COM	China	24342	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	FandaChem@Gmail.com	China	3315	55
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	340	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29858	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2957	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58

Supplier	Advantage
Yangzhou Qinyuan Pharmatech Co.,ltd	58
QUALITY CONTROL SOLUTIONS LTD.	58
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Hangzhou FandaChem Co.,Ltd.	55
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58

View Lastest Price from 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-04	1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 55314-16-4	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2024-10-31	1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 55314-16-4	US $0.00 / g	10g	98%	10tons	Yangzhou Qinyuan Pharmatech Co.,ltd
2021-10-26	1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 55314-16-4	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
55314-16-4
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
55314-16-4
US $0.00 / g
98%
Yangzhou Qinyuan Pharmatech Co.,ltd

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
55314-16-4
US $1.10 / g
99.00%
Dideu Industries Group Limited

55314-16-4(1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one)Related Search:

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2-DiMethylaMino-1-(3-pyridyl)-2-propene-1-one 3-[3-(Dimethylamino)acryloyl]pyridine 2-(Dimethylamino)ethenyl 3-Pyridyl Ketone 3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one 3-[3-(Dimethylamino)acryloyl]pyridine (E)-3-DIMETHYLAMINO-1-PYRIDIN-3-YL-PROPENONE 3-diMethylaMino-1-(3-pyridyl)-2-propen-1-one, 3-(N,N-diMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one, 3-(diMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one 3-(Dimethylamino)-1-(3-pyridinyl)-2-propen-1-one (2E)-3-(Dimethylamino)-1-(3-pyridinyl)-2-propen-1-one (E)-3-dimethylamino-1-(3-pyridyl)prop-2-en-1-one 3-dimethylamino-1-(3-pyridyl)prop-2-en-1-one 3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one 4G-951 Imatinib Dimethylamino Impurity Imatinib USP Impurity A 3-(DIMETHYLAMINO)-1-(3-PYRIDINYL)-2-PROPEN-1-ONE 1-(3-PYRIDYL)-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE 3-(Dimethylamino)-1-pyridin-3-ylprop-2-en-1-one 2-propen-1-one,3-（dimethylamino）-1-（3-pyridinyl） 3-Dimethylamino-1-(pyridin-3-yl)propenone 1-(3-PYRIDYL)-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE 95% 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one ,97% 2-(DiMethylaMino)vinyl 3-Pyridyl Ketone Imatinib Related Compound A 3-(Dimethylamino)-1-(3-pyridinyl)-2-propene-1-one Imatinib Impurity 19 Imatinib EP Impurity A 2-(Dimethylamino)vinyl3-PyridylKetone> Imatinib Dimethylamino Impurity Certified Reference Standard 2-(Dimethylamino)ethenyl 3-Pyridyl Ketone 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one ISO 9001：2015 REACH Imatinib EP Impurity A (Imatinib Dimethylamino Impurity) Nilotinib??Intermediates?B 1 - (3-pyridyl) - 3 - (dimethylamino) - 2-propene-1-one 3-Dimethylamino-1-pyridin-3-yl-pr Imatinib Dimethylamino ImpurityQ: What is Imatinib Dimethylamino Impurity Q: What is the CAS Number of Imatinib Dimethylamino Impurity Q: What is the storage condition of Imatinib Dimethylamino Impurity Q: What are the applications of Imatinib Dimethylamino Impurity 2-(Dimethylamino)vinyl 3-Pyridyl Ketone, ≥ 95.0% Imatinib Impurity 74 55314-16-4 Intermediate of Imatinib Chemical Amines Amines Bases & Related Reagents Intermediates & Fine Chemicals Nucleotides Pharmaceuticals Heterocycles Intermediates