ChemicalBook >> CAS DataBase List >>6-AZAURIDINE
6-AZAURIDINE
- CAS No.
- 54-25-1
- Chemical Name:
- 6-AZAURIDINE
- Synonyms
- azauridine;6-azuridine;azur;6-azur;nsc32074;AZURIDINE;Aids008706;Aids-008706;6-AZAURIDINE;ribo-azuracil
- CBNumber:
- CB1413830
- Molecular Formula:
- C8H11N3O6
- Molecular Weight:
- 245.19
- MDL Number:
- MFCD00006472
- MOL File:
- 54-25-1.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Melting point | 157-159 °C(lit.) |
|---|---|
| Boiling point | 388.15°C (rough estimate) |
| Density | 1.4866 (rough estimate) |
| refractive index | 1.7950 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated), Pyridine (Slightly), Water |
| form | Powder |
| pka | 6.70(at 25℃) |
| color | White |
| Water Solubility | It is soluble in water. |
| Merck | 14,904 |
| Stability | Hygroscopic |
| InChIKey | WYXSYVWAUAUWLD-YGWZKZRUSA-N |
| CAS DataBase Reference | 54-25-1(CAS DataBase Reference) |
| FDA UNII | 7BVB29RCPR |
| NCI Drug Dictionary | 6-azauridine |
| UNSPSC Code | 41106305 |
| NACRES | NA.51 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H351 |
| Precautionary statements | P201-P280-P301+P312-P302+P352+P312-P304+P340+P312-P308+P313 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-40 |
| Safety Statements | 22-36 |
| WGK Germany | 3 |
| RTECS | XY8575000 |
| HS Code | 29349990 |
| Hazardous Substances Data | 54-25-1(Hazardous Substances Data) |
| Toxicity | LD50 oral in quail: > 316mg/kg |
6-AZAURIDINE price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A1882 | 6-Azauridine | 54-25-1 | 1g | $86.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | A1882 | 6-Azauridine | 54-25-1 | 5g | $481 | 2024-03-01 | Buy |
| TCI Chemical | A0559 | 6-Azauridine >99.0%(HPLC) | 54-25-1 | 10mg | $30 | 2024-03-01 | Buy |
| Alfa Aesar | J61309 | 6-Azauridine | 54-25-1 | 1g | $118.65 | 2024-03-01 | Buy |
| Alfa Aesar | J61309 | 6-Azauridine | 54-25-1 | 5g | $471.65 | 2024-03-01 | Buy |
6-AZAURIDINE Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
6-Azauridine (AzUrd) blocks the conversion of orotic acid into UMP and it is used in antiviral studies.
Uses
6-Azauridine can be applied in antiviral studies. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. It is also used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Uses
Research on cell formation and cancer.
Definition
ChEBI: 6-azauridine is a N-glycosyl-1,2,4-triazine. It has a role as an antineoplastic agent, an antimetabolite and a drug metabolite.
General Description
6-Azauridine is a pyrimidine nucleoside analog.
Biochem/physiol Actions
6-azauridine is a prodrug, upon conversion to 6-aza-UMP, inhibits uridine monophosphate synthase (UMPS). It is a broad spectrum anti-metabolite. It interferes with pyrimidine biosynthesis and affects the cellular nucleic acid levels. It is considered as a antineoplastic metabolite. It inhibits RNA viruses like chikungunya virus, semliki forest virus, and human coronavirus. It significantly inhibits the growth of Cryptosporidium parasites.
6-AZAURIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 120)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29875 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22787 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 9983 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 |
View Lastest Price from 6-AZAURIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | 6-Azauridine
54-25-1
|
US $40.00 / mg | 100% | 10g | TargetMol Chemicals Inc. | ||
 |
2019-07-06 | 6-AZAURIDINE
54-25-1
|
US $1.00 / kg | 1kg | 95%-99% | as request | Career Henan Chemical Co | |
 |
2019-07-06 | 6-AZAURIDINE
54-25-1
|
US $1.00 / kg | 1kg | 95%-99% | 100kg | Career Henan Chemical Co |
-
- 6-Azauridine
54-25-1
- US $40.00 / mg
- 100%
- TargetMol Chemicals Inc.
-
- 6-AZAURIDINE
54-25-1
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co
-
- 6-AZAURIDINE
54-25-1
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co
54-25-1(6-AZAURIDINE)Related Search:
azur
nsc32074
ribo-azuracil
2-(beta-D-ribofuranosyl)-1,2,4-triazine-3,5-diol
2-β-d-ribofuranosyl-1,2,4-triazine-3,5(2h,4h)-dione
AZURIDINE
TRIAZINE-3,5-DIONE,2-BETA-D-RIBOFURANOSYL-
6-Azauracil riboside, 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione
Ribo-Azauracil
1,2,4-Triazine-3,5(2H,4H)-dione, 2-.beta.-D-ribofuranosyl-
Aids008706
Aids-008706
2-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione
1,2,4-Triazine-3,5(2H,4H)-dione,2-b-D-ribofuranosyl-
Rib-Azauracil
6-AZAURIDINE CRYSTALLINE
6-AZA-2,4-DIHYDROXYPYRIMIDINE RIBOSIDE
6-AZAURIDINE MONOHYDRATE
6-AZAURACIL RIBOSIDE
6-AZAURACIL RIBOSIDE MONOHYDRATE
6-AZAURIDINE
2-BETA-D-RIBOFURANOSYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE
AZAURIDINE, 6-
2-beta-d-ribofuranosyl-1,2,4-triazin-3,5(2h,4h)-dion
2-beta-d-ribofuranosyl-as-triazine-3,5(2h,4h)-dione
3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazineriboside
4h)-dione,2-beta-d-ribofuranosyl-as-triazine-5(2h
4-triazine-3,5(2h,4h)-dione,2-beta-d-ribofuranosyl-2
6-azauracil1-riboside
6-azauracil-beta-d-riboside
6-azauracilribosid
6-azur
6-Azauridine>
1,2,4-Triazine-3,5(2H,4H)-dione, 2-β-D-ribofuranosyl-
6-AZAURIDINE USP/EP/BP
6-Azauridine, antimetabolic antineoplastic agent
6-azuridine
azauridine
1-(beta-D-Ribofuranosyl)-6-azauracil
54-25-1
C8H11N3O6H2O
C8H11N3O6
Biochemicals and Reagents
BioChemical
Nucleosides, Nucleotides, Oligonucleotides
Nucleoside Analogs
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Pyridines, Pyrimidines, Purines and Pteredines