ANTI-L/S-AFADIN
- CAS No.
- Chemical Name:
- ANTI-L/S-AFADIN
- Synonyms
- ANTI-L/S-AFADIN;Anti-l/s-Afadin antibody produced in rabbit
- CBNumber:
- CB1417964
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03455383
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Safety Statements | 23-24/25 |
|---|---|
| WGK Germany | - |
ANTI-L/S-AFADIN price More Price(1)
ANTI-L/S-AFADIN Chemical Properties,Uses,Production
Uses
Anti-l/s-Afadin antibody produced in rabbit has been used in :
- immunocytochemistry
- immunohistochemistry
- immunoprecipitation
General Description
S-Afadin is a protein which lacks both the third proline-rich and the F-actin binding regions and is homologous to the human AF-6 (ALL-1 fusion partner from chromosome 6) gene product. Anti-l/s-Afadin is developed in rabbit using a synthetic peptide of rat afadin.
Biochem/physiol Actions
s-Afadin binds to several cytoplasmic proteins such as the small guanosine triphosphatase (GTPase) Ras, the tight junction protein ZO-1 2 and the vinculin binding protein ponsin/ sorbin and SH3 domain containing 1 (SH3P12). In addition, l-afadin also binds through its PDZ several integral membrane components such as the Ca2+ -independent homophilic immunoglobulin-like nectin, the junctional adhesion molecule (JAM)4 and a subset of the EphB receptor protein-tyrosine kinases.
ANTI-L/S-AFADIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-L/S-AFADIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |