ANTI-L/S-AFADIN 化学特性,用途語,生産方法
使用
Anti-l/s-Afadin antibody produced in rabbit has been used in :
- immunocytochemistry
- immunohistochemistry
- immunoprecipitation
一般的な説明
S-Afadin is a protein which lacks both the third proline-rich and the F-actin binding regions and is homologous to the human AF-6 (ALL-1 fusion partner from chromosome 6) gene product. Anti-l/s-Afadin is developed in rabbit using a synthetic peptide of rat afadin.
Biochem/physiol Actions
s-Afadin binds to several cytoplasmic proteins such as the small guanosine triphosphatase (GTPase) Ras, the tight junction protein ZO-1 2 and the vinculin binding protein ponsin/ sorbin and SH3 domain containing 1 (SH3P12). In addition, l-afadin also binds through its PDZ several integral membrane components such as the Ca2+ -independent homophilic immunoglobulin-like nectin, the junctional adhesion molecule (JAM)4 and a subset of the EphB receptor protein-tyrosine kinases.
ANTI-L/S-AFADIN 上流と下流の製品情報
原材料
準備製品