LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT)

CAS No.
95991-05-2
Chemical Name:
LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT)
Synonyms
lipid A, diphosphoryl;LIPID A, DIPHOSPHORYL FROM SALMONELLA*MI NNESOTA RE-;LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT);LIPID A, DIPHOSPHORYL FROM SALMONELLA MINNESOTA RE-595 (R MUTANTS);lipid a, diphosphoryl from salmonella enterica serotype minnesota re 595 (re mutant);2-deoxy-6-O-<2-deoxy-2-<(R)-3-dodecanoyloxytetradecanoylamino>-3-O-<(R)-3-tetradecanoyloxytetradecanoyl>-β-D-glucopyranosyl>-3-O-<(R)-3-hydroxytetradecanoyl>-2-<(R)-3-hydroxytetradecanoylamino>-α-D-glucopyranose 1,4'-bis(phosphate);α-D-Glucopyranose, 2-deoxy-6-O-[2-deoxy-2-[[(3R)-1-oxo-3-[(1-oxododecyl)oxy]tetradecyl]amino]-3-O-[(3R)-1-oxo-3-[(1-oxotetradecyl)oxy]tetradecyl]-4-O-phosphono-β-D-glucopyranosyl]-2-[[(3R)-3-hydroxy-1-oxotetradecyl]amino]-, 1-(dihydrogen phosphate) 3-[(3R)-3-hydroxytetradecanoate];α-D-Glucopyranose, 2-deoxy-6-O-[2-deoxy-2-[[(3R)-1-oxo-3-[(1-oxododecyl)oxy]tetradecyl]amino]-3-O-[(3R)-1-oxo-3-[(1-oxotetradecyl)oxy]tetradecyl]-4-O-phosphono-β-D-glucopyranosyl]-2-[[(3R)-3-hydroxy-1-oxotetradecyl]amino]-, 1-(dihydrogen phosphate) 3-[(3R)-3-hydroxytetradecanoate]
CBNumber:
CB1457188
Molecular Formula:
C94H178N2O25P2
Molecular Weight:
1798.37
MDL Number:
MFCD07369021
MOL File:
95991-05-2.mol

LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) Properties

Density 1.13±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 1.73±0.10(Predicted)

SAFETY

Risk and Safety Statements

Hazard Codes  Xn
WGK Germany  3

LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L5399 Lipid A, diphosphoryl from Escherichia coli F583 (Rd mutant) 95991-05-2 1MG $193 2023-06-20 Buy
Sigma-Aldrich L5399 Lipid A, diphosphoryl from Escherichia coli F583 (Rd mutant) 95991-05-2 5MG $790 2023-06-20 Buy
Sigma-Aldrich L0774 Lipid A, diphosphoryl from Salmonella enterica serotype minnesota Re 595 (Re mutant) 95991-05-2 1mg $322 2023-01-07 Buy
American Custom Chemicals Corporation LIP0003692 LIPID A DIPHOSPHORYL 95.00% 95991-05-2 5MG $501.37 2021-12-16 Buy
Product number Packaging Price Buy
L5399 1MG $193 Buy
L5399 5MG $790 Buy
L0774 1mg $322 Buy
LIP0003692 5MG $501.37 Buy

LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) Chemical Properties,Uses,Production

Uses

Lipid A, diphosphoryl from?Escherichia coli?F583 (Rd mutant) has been used:

  • to study the effect of various lipid A molecules on lung pericyte proliferation in vitro
  • to test on THP-1 and J774A.1 cells for neopterin and nitrite formation respectively
  • as lipopolysaccharides (LPS) derivatives in binding experiments
  • to stimulate the spleen cells and as a mitogen stimulation for toll like receptor 4 (TLR4)

General Description

Lipid A is the fundamental structure of lipopolysaccharides (LPS), present in bacteria.

Biochem/physiol Actions

Lipid A is mainly essential for the robust immunostimulatory activities of lipopolysaccharides (LPS) in human. Lipid A is the hydrophobic domain of LPS helps in anchoring LPS to the plasma membrane of bacteria. It is immunologically active and an important constituent of LPS recognised by immune system.

LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) Preparation Products And Raw materials

Raw materials

Preparation Products

LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
Supplier Advantage
Sigma-Aldrich 80
LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) LIPID A, DIPHOSPHORYL FROM SALMONELLA MINNESOTA RE-595 (R MUTANTS) LIPID A, DIPHOSPHORYL FROM SALMONELLA*MI NNESOTA RE- lipid a, diphosphoryl from salmonella enterica serotype minnesota re 595 (re mutant) lipid A, diphosphoryl 2-deoxy-6-O-<2-deoxy-2-<(R)-3-dodecanoyloxytetradecanoylamino>-3-O-<(R)-3-tetradecanoyloxytetradecanoyl>-β-D-glucopyranosyl>-3-O-<(R)-3-hydroxytetradecanoyl>-2-<(R)-3-hydroxytetradecanoylamino>-α-D-glucopyranose 1,4'-bis(phosphate) α-D-Glucopyranose, 2-deoxy-6-O-[2-deoxy-2-[[(3R)-1-oxo-3-[(1-oxododecyl)oxy]tetradecyl]amino]-3-O-[(3R)-1-oxo-3-[(1-oxotetradecyl)oxy]tetradecyl]-4-O-phosphono-β-D-glucopyranosyl]-2-[[(3R)-3-hydroxy-1-oxotetradecyl]amino]-, 1-(dihydrogen phosphate) 3-[(3R)-3-hydroxytetradecanoate] α-D-Glucopyranose, 2-deoxy-6-O-[2-deoxy-2-[[(3R)-1-oxo-3-[(1-oxododecyl)oxy]tetradecyl]amino]-3-O-[(3R)-1-oxo-3-[(1-oxotetradecyl)oxy]tetradecyl]-4-O-phosphono-β-D-glucopyranosyl]-2-[[(3R)-3-hydroxy-1-oxotetradecyl]amino]-, 1-(dihydrogen phosphate) 3-[(3R)-3-hydroxytetradecanoate] 95991-05-2 C94H178N2O25P2 BioChemical Biochemicals and Reagents Glycolipids Complex Lipids Others Lipids Complex Lipids Glycolipids Others