ChemicalBook >> CAS DataBase List >>6-HYDROXY-7-METHOXYCOUMARIN
6-HYDROXY-7-METHOXYCOUMARIN
- CAS No.
- 776-86-3
- Chemical Name:
- 6-HYDROXY-7-METHOXYCOUMARIN
- Synonyms
- ISOSCOPOLETIN;ISOSCOPOLETINE;Isoscopolamine;7-Methoxyesculetin;6-O-Demethylscoparone;esculetin 7-methyl ether;6-HYDROXY-7-METHYLCOUMARIN;6-HYDROXY-7-METHOXYCOUMARIN;7-METHOXY-6-HYDROXYCOUMARIN;6-hudroxy-7-methoxycoumarin
- CBNumber:
- CB1472785
- Molecular Formula:
- C10H8O4
- Molecular Weight:
- 192.17
- MDL Number:
- MFCD00016976
- MOL File:
- 776-86-3.mol
- MSDS File:
- SDS
Last updated:2023-05-25 18:01:00
| Melting point | 206-208°C |
|---|---|
| Boiling point | 413.5±45.0 °C(Predicted) |
| Density | 1.37 g/cm3 |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO: soluble |
| form | Solid |
| pka | 8.94±0.20(Predicted) |
| color | Pale Beige to Light Beige |
| LogP | 0.830 (est) |
| CAS DataBase Reference | 776-86-3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 |
| Hazard Codes | Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| F | 8 |
| HS Code | 29322090 |
6-HYDROXY-7-METHOXYCOUMARIN price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL85752 | Isoscopoletin phyproof? Reference Substance | 776-86-3 | 20MG | $344 | 2024-03-01 | Buy |
| TRC | H517345 | 6-Hydroxy-7-methoxycoumarin | 776-86-3 | 2.5mg | $45 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FI67110 | Isoscopoletin | 776-86-3 | 100mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FI67110 | Isoscopoletin | 776-86-3 | 10mg | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FI67110 | Isoscopoletin | 776-86-3 | 25mg | $75 | 2021-12-16 | Buy |
6-HYDROXY-7-METHOXYCOUMARIN Chemical Properties,Uses,Production
Description
Isoscopolamine is an antiasthmatic drug, which has the effect of relaxing smooth muscle and antihistamine. It can be used clinically in patients with chronic bronchitis and bronchial asthma.
Chemical Properties
Yellow needle-like crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Dengzhanhua, Rhododendron.
Uses
Isoscopolamine has anti-inflammatory, antioxidant, improving myocardial ischemia, anti-arrhythmic effects.
Definition
ChEBI: Isoscopoletin is a hydroxycoumarin that is esculetin in which the hydroxy group at position 7 is replaced by a methoxy group. It is the major primary metabolite of scoparone. It has a role as a plant metabolite. It is a hydroxycoumarin and an aromatic ether. It is functionally related to an esculetin.
Biological Activity
Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active ingredient in Artemisia argyi. It has a significant inhibitory effect on cell proliferation with IC50 values of 4.0 μM and 1.6 μM against human CCRF-CEM leukemia cells and drug-resistant subline CEM/ADR5000, respectively. It (6-Hydroxy-7-methoxycoumarin) has the activity of inhibiting HBV replication.
6-HYDROXY-7-METHOXYCOUMARIN Preparation Products And Raw materials
Raw materials
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Preparation Products
Global( 167)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 953 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10319 | 58 |
View Lastest Price from 6-HYDROXY-7-METHOXYCOUMARIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Isoscopoletin
776-86-3
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2021-05-29 | 6-HYDROXY-7-METHOXYCOUMARIN USP/EP/BP
776-86-3
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-06 | 6-HYDROXY-7-METHOXYCOUMARIN
776-86-3
|
US $1.00 / kg | 1g | 99% | 100KG | Career Henan Chemical Co |
-
- Isoscopoletin
776-86-3
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- 6-HYDROXY-7-METHOXYCOUMARIN USP/EP/BP
776-86-3
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- 6-HYDROXY-7-METHOXYCOUMARIN
776-86-3
- US $1.00 / kg
- 99%
- Career Henan Chemical Co
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7-METHOXY-6-HYDROXYCOUMARIN
6-HYDROXY-7-METHYLCOUMARIN
6-HYDROXY-7-METHOXYCOUMARIN
ISOSCOPOLETIN
ISOSCOPOLETINE
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6-Hydroxy-7-methyl coumarin-(Isoscopoletin) -
ISOSCOPOLETIN (6-HYDROXY-7-METHYLCOUMARIN)
7-Methoxyesculetin, Esculetin 7-methyl ether, Isoscopoletin
6-Hydroxy-7-methoxy-2H-1-benzopyran-2-one
6-O-Demethylscoparone
6-hydroxy-7-methoxy-chromen-2-one
6-hydroxy-7-methoxychromen-2-one
6-hydroxy-7-methoxy-2H-chromen-2-one
7-Methoxyesculetin
esculetin 7-methyl ether
6-hudroxy-7-methoxycoumarin
Isoscopoletin (6-Hydroxy-7-methoxycoumarin)
2H-1-Benzopyran-2-one, 6-hydroxy-7-methoxy-
6-HYDROXY-7-METHOXYCOUMARIN USP/EP/BP
6-Hydroxy-7-methoxycoumarin (Isoscopoletine)
Isoscopolamine
776-86-3
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