Sodium acetate trihydrate

Sodium acetate trihydrate Properties

Melting point	58 °C
Boiling point	>400°C
bulk density	900kg/m3
Density	1,45 g/cm³
Flash point	>250°C
storage temp.	Store at +5°C to +30°C.
solubility	H₂O: 3 M at 20 °C, clear, colorless
form	Solid
color	White
Odor	Slight acetic acid
PH Range	8.5 - 10 at 408 g/l at 25 °C
PH	7.5-9.0 (25℃, 50mg/mL in H2O)
pka	4.76 (acetic acid)(at 25℃)
Water Solubility	762 g/L (20 ºC)
λmax	λ: 260 nm Amax: ≤0.01 λ: 280 nm Amax: ≤0.01
Merck	14,8571
BRN	3732037
Stability	Stable. Incompatible with strong oxidizing agents, halogens.
InChIKey	AYRVGWHSXIMRAB-UHFFFAOYSA-M
LogP	-0.285 (est)
CAS DataBase Reference	6131-90-4(CAS DataBase Reference)
FDA UNII	4550K0SC9B
NIST Chemistry Reference	Sodium acetate trihydrate(6131-90-4)
EPA Substance Registry System	Acetic acid, sodium salt, trihydrate (6131-90-4)
UNSPSC Code	41116107
NACRES	NB.21

SAFETY

Risk and Safety Statements

Hazard Codes

Xi

Risk Statements

36/37/38

Safety Statements

24/25-36-26

WGK Germany

1

RTECS

AJ4580000

Autoignition Temperature

607 °C

TSCA

Yes

HS Code

29152200

Toxicity

LD50 orally in Rabbit: 3530 mg/kg LD50 dermal Rabbit > 10000 mg/kg

NFPA 704

	1
1		0

Sodium acetate trihydrate price More Price(68)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SX0255	Sodium acetate trihydrate Meets ACS Specifications GR ACS	6131-90-4	12kg	$407	2024-03-01	Buy
Sigma-Aldrich	PHR2618	Sodium Acetate Trihydrate Pharmaceutical Secondary Standard; Certified Reference Material	6131-90-4	2G	$267	2024-03-01	Buy
Sigma-Aldrich	7610-OP	OmniPur Sodium Acetate, Trihydrate - CAS 6131-90-4 - Calbiochem	6131-90-4	500g	$45	2024-03-01	Buy
Sigma-Aldrich	5.43833	Sodium acetate trihydrate for HPLC LiChropur?	6131-90-4	100G	$138	2024-03-01	Buy
Sigma-Aldrich	32318	Sodium acetate trihydrate puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5%	6131-90-4	500g	$49.6	2024-03-01	Buy

Product number	Packaging	Price	Buy
SX0255	12kg	$407	Buy
PHR2618	2G	$267	Buy
7610-OP	500g	$45	Buy
5.43833	100G	$138	Buy
32318	500g	$49.6	Buy

Sodium acetate trihydrate Chemical Properties,Uses,Production

Chemical Properties

Sodium acetate trihydrate is the trihydrate sodium salt oaf acetic acid. It is a colorless, odorless crystals that can be weathered in the air. Soluble in water and ether, pH of 0.1M aqueous solution is 8.9. moderately soluble in ethanol, 5.3 g/100mL. Anhydrous Sodium acetate occurs as colorless, transparent crystals or a granular crystalline powder with a slight acetic acid odor.

Uses

Sodium acetate trihydrate is used in various applications. It is used as a buffer of a pH range in between to 4.0 to 6.0. It is also used in the purification and precipitation of nucleic acids and in protein crystallization. It is used as a mordant dyeing, as a pickling agent in chrome tanning, as a neutralizer in waste streams containing sulfuric acid, in the textile industry and as a photoresist while using aniline dyes. It plays an important role to retard vulcanization of chloroprene in synthetic rubber production. It is a precursor to prepare ester from alkyl halide. Other applications are in photography, as an additive to food, in purification of glucose, in preservation of meat, in tanning, and as a dehydrating agent. In analytical chemistry it is used to prepare buffer solution.

Definition

ChEBI: Sodium acetate trihydrate is a hydrate. It contains a sodium acetate.

Preparation

Sodium acetate is prepared by reacting sodium hydroxide or sodium carbonate with acetic acid in aqueous solution. The solution is evaporated to obtain hydrated crystals of sodium acetate.
NaOH + CH3COOH → CH3COONa + H2O
Na2CO3 + CH3COOH → 2CH3COONa + CO2 + H2O

General Description

Sodium acetate trihydrate can be obtained from the crystallization of sodium acetate in water. On heating at 75°C, it melts, while on heating above 120°C it loses water of crystallization and gets converted into anhydrous form. The hyperfine proton and ¹³C splittings have been evaluated by recording ESR spectra of its irradiated single crystals. ESR studies suggested the existence of trapped methyl radicals. Its crystals are monoclinic and its crystal structure has been investigated by photographic methods. Unit cell parameters were evaluated.

Pharmaceutical Applications

Sodium acetate is used as part of a buffer system when combined with acetic acid in various intramuscular, intravenous, topical, ophthalmic, nasal, oral, otic, and subcutaneous formulations. It may be used to reduce the bitterness of oral pharmaceuticals. It can be used to enhance the antimicrobial properties of formulations; it has been shown to inhibit the growth of S. aureus and E. coli, but not C. albicans in protein hydrolysate solutions. It is widely used in the food industry as a preservative. Sodium acetate has also been used therapeutically for the treatment of metabolic acidosis in premature infants, and in hemodialysis solutions.

Biochem/physiol Actions

Sodium acetate trihydrate (SAT) is a phase change material (PCM) that can be easily combined with the preparation of domestic hot water, space heating, solar heating, and radiant floor heating systems. The hydrated salt of SAT possesses high latent heat density and thus can be used for low-temperature heat storage.

Safety

Sodium acetate is widely used in cosmetics, foods, and pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material.
A short-term feeding study in chickens with a diet supplemented with 5.44% sodium acetate showed reduced growth rates that were attributed to the sodium content.(9) Sodium acetate is poisonous if injected intravenously, is moderately toxic by ingestion, and is an irritant to the skin and eyes.
LD50 (rat, oral): 3.53 g/kg
LD50 (mouse, IV): 0.38 g/kg
LD50 (mouse, SC): 8.0 g/kg

storage

Sodium acetate should be stored in airtight containers.

Incompatibilities

Sodium acetate reacts with acidic and basic components. It will react violently with fluorine, potassium nitrate, and diketene.

Regulatory Status

GRAS listed. Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (injections, nasal, otic, ophthalmic, and oral preparations).

References

[1] http://www.europlat.org
[2] http://www.rxlist.com/sodium-acetate-drug.htm
[3] http://cosmetics.specialchem.com
[4] http://cecri.csircentral.net/2710/1/036-96.pdf

Sodium acetate trihydrate Preparation Products And Raw materials

Raw materials

Acetic acid solution Acetic acid Sodium hydroxide Activated carbon Sodium carbonate

Preparation Products

Gardenia blue pigment Pigment Yellow 83 5-Ethyl-2-thiophenecarboxaldehyde BISPYRAZOLONE LEAD PHOSPHITE, DIBASIC

6-HYDROXY-7-METHOXYCOUMARIN Pigment Red 32 Pigment Red 13 Pigment Yellow 65 o-Anisic acid

VINYL STEARATE 3-(2-FURYL)ISOXAZOL-5-AMINE Pigment Red 175 RHODINYL ACETATE softener IS

Phenethyl acetate Sodium diacetate 8-METHOXYCOUMARIN D-alpha-Tocopheryl acetate Geranyl acetate

3-Amino-5-phenylpyrazole 2,6-Dithiopurine ACID BLUE 92 glyceryl ethercarboxylic acid salt 3,3'-Dihydroxybenzidine

6-METHOXYCOUMARIN Cefotaxime PALMITIC ACID VINYL ESTER 2-Acetyl pyrrole 1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE

2-AMINO-4-(4-CHLORO-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER 5-METHYL-4-ISOXAZOLECARBONYL CHLORIDE 4-Hydroxy-3-methoxystyrene C. I. Pigment Red 258 7-isopropyl-4-methyloxepan-2-one

5-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)METHYL]-2-FURALDEHYDE 6-AMINO-5-NITROSO-3-METHYLURACIL Cephalothin sodium Coumarin 30 ISOXANTHOPTERIN

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Sodium acetate trihydrate Suppliers

Global( 743)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jiangsu Kolod Food Ingredients Co.,Ltd.	+8618805133257	sales3257@jskolod.com	China	132	60
Jiangsu Boquan Biotechnology Co., Ltd.	+86-18168774353	boquanshengwu003@boquansw.com	China	248	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531157085	abby@chuanghaibio.com	China	8808	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-15536356810	1022@dideu.com	China	3882	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	7906	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	7859	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5868	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18137	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+86-17396673057	linda@tnjone.com	China	1143	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3692	58

Supplier	Advantage
Jiangsu Kolod Food Ingredients Co.,Ltd.	60
Jiangsu Boquan Biotechnology Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Shanghai UCHEM Inc.	58
Shaanxi Dideu Medichem Co. Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58

View Lastest Price from Sodium acetate trihydrate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-23	Sodium acetate trihydrate 6131-90-4	US $1.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-04-17	Sodium Acetate 6131-90-4	US $1500.00 / KG	1KG	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
2025-04-15	Sodium acetate trihydrate 6131-90-4	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd

Sodium acetate trihydrate
6131-90-4
US $1.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Sodium Acetate
6131-90-4
US $1500.00 / KG
99.0% min
Shaanxi Dideu Medichem Co. Ltd

Sodium acetate trihydrate
6131-90-4
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Sodium acetate trihydrate Spectrum

Sodium acetate trihydrate(6131-90-4)IR1 Sodium acetate trihydrate(6131-90-4)IR2 Sodium acetate trihydrate(6131-90-4)Raman Sodium acetate trihydrate(6131-90-4)ESR

6131-90-4(Sodium acetate trihydrate)Related Search:

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MANGANESE(II) ACETATE TETRAHYDRATE MANGANESE(II) ACETATE YTTRIUM ACETATE

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