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NFAT Transcription Factor Regulator

CAS No.
245747-71-1
Chemical Name:
NFAT Transcription Factor Regulator
Synonyms
NFAT Transcription Factor Regulator;NFAT Transcription Factor Regulator-1;NFAT Transcription Factor Regulator 1,NFAT Transcription Factor Regulator1;N-(4-(5-(Difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-3-fluoroisonicotinamide;4-Pyridinecarboxamide, N-[4-[5-(difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-
CBNumber:
CB14797086
Molecular Formula:
C17H10F6N4O2
Molecular Weight:
416.28
MDL Number:
MFCD31715449
MOL File:
245747-71-1.mol
Last updated:2024-07-02 08:55:01

NFAT Transcription Factor Regulator Properties

Boiling point 408.4±45.0 °C(Predicted)
Density 1.53±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 150 mg/mL (360.33 mM);Water : < 0.1 mg/mL (insoluble)
form Solid
pka 9.85±0.70(Predicted)
color Light yellow to yellow

NFAT Transcription Factor Regulator price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0063874 NFATTranscriptionFactorRegulator-1 99.37% 245747-71-1 5mg $175 2021-12-16 Buy
ChemScene CS-0063874 NFATTranscriptionFactorRegulator-1 99.37% 245747-71-1 10mg $295 2021-12-16 Buy
ChemScene CS-0063874 NFATTranscriptionFactorRegulator-1 99.37% 245747-71-1 50mg $880 2021-12-16 Buy
Biorbyt Ltd orb572897 NFAT Transcription Factor Regulator 245747-71-1 100mg $1431.4 2021-12-16 Buy
ChemScene CS-0063874 NFATTranscriptionFactorRegulator-1 99.37% 245747-71-1 100mg $1500 2021-12-16 Buy
Product number Packaging Price Buy
CS-0063874 5mg $175 Buy
CS-0063874 10mg $295 Buy
CS-0063874 50mg $880 Buy
orb572897 100mg $1431.4 Buy
CS-0063874 100mg $1500 Buy

NFAT Transcription Factor Regulator Chemical Properties,Uses,Production

Biological Activity

NFAT Transcription Factor Regulator-1 is an inhibitor of IL-2 synthesis with IC50 of 182 nM.

in vitro

NFAT Transcription Factor Regulator-1 (compound example 19) inhibits IL-2 synthesis with an IC 50 of 182 nM. NFAT Transcription Factor Regulator-1 inhibits human and rat PBMC proliferation with IC 50 s of 82 and 146 nM, respectively. NFAT Transcription Factor Regulator-1 is able to inhibit IL-4 and IL-5 production in human T-cell lines with similar potency to its effects on IL -2 release.

target

IL-2

< span> 182 nM (IC 50 )

NFAT Transcription Factor Regulator Preparation Products And Raw materials

Raw materials

Preparation Products

NFAT Transcription Factor Regulator Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3732 55
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29795 68
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9412 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10011 58
Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 63720 58
NFAT Transcription Factor Regulator NFAT Transcription Factor Regulator-1 4-Pyridinecarboxamide, N-[4-[5-(difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro- NFAT Transcription Factor Regulator 1,NFAT Transcription Factor Regulator1 N-(4-(5-(Difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-3-fluoroisonicotinamide 245747-71-1