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NFAT Transcription Factor Regulator

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NFAT Transcription Factor Regulator Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:NFAT Transcription Factor Regulator-1
CAS:245747-71-1
Purity:98.00% Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；200 mg；5 mg；50 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:NFAT Transcription Factor Regulator-1
CAS:245747-71-1
Purity:98% Package:$83.9/1mg;$175.9/5mg;$295.9/10mg;$880.9/50mg;$1500.9/100mg;Bulk package Remarks:98%
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Email: klq@cw-bio.com
Products Intro: Product Name:NFAT transcription factor regulator 1
CAS:245747-71-1
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
Company Name: Beijing Solarbio Science & Tecnology Co., Ltd.  
Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Products Intro: Product Name:NFAT Transcription Factor Regulator-1
CAS:245747-71-1
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Products Intro: Product Name:NFAT Transcription Factor Regulator
CAS:245747-71-1
Purity:97.0% Package:5mg
NFAT Transcription Factor Regulator Basic information
Product Name:NFAT Transcription Factor Regulator
Synonyms:NFAT Transcription Factor Regulator;NFAT Transcription Factor Regulator-1;4-Pyridinecarboxamide, N-[4-[5-(difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-;NFAT Transcription Factor Regulator 1,NFAT Transcription Factor Regulator1;N-(4-(5-(Difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-3-fluoroisonicotinamide
CAS:245747-71-1
MF:C17H10F6N4O2
MW:416.28
EINECS:
Product Categories:
Mol File:245747-71-1.mol
NFAT Transcription Factor Regulator Structure
NFAT Transcription Factor Regulator Chemical Properties
Boiling point 408.4±45.0 °C(Predicted)
density 1.53±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 150 mg/mL (360.33 mM);Water : < 0.1 mg/mL (insoluble)
form Solid
pka9.85±0.70(Predicted)
color Light yellow to yellow
Safety Information
MSDS Information
NFAT Transcription Factor Regulator Usage And Synthesis
Biological ActivityNFAT Transcription Factor Regulator-1 is an inhibitor of IL-2 synthesis with IC50 of 182 nM.
in vitro

NFAT Transcription Factor Regulator-1 (compound example 19) inhibits IL-2 synthesis with an IC 50 of 182 nM. NFAT Transcription Factor Regulator-1 inhibits human and rat PBMC proliferation with IC 50 s of 82 and 146 nM, respectively. NFAT Transcription Factor Regulator-1 is able to inhibit IL-4 and IL-5 production in human T-cell lines with similar potency to its effects on IL -2 release.

target

IL-2

< span> 182 nM (IC 50 )

NFAT Transcription Factor Regulator Preparation Products And Raw materials
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