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Metizolam

Metizolam Structure
Metizolam structure
CAS No.
40054-68-0
Chemical Name:
Metizolam
Synonyms
Metizolam;Metizolam, Desmethyletizolam;Metizolam (1.0 mg/mL in Methanol);6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, 4-(2-chlorophenyl)-2-ethyl-;Metizolam 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, 4-(2-chlorophenyl)-2-ethyl-
CBNumber:
CB14820595
Molecular Formula:
C16H13ClN4S
Molecular Weight:
328.82
MDL Number:
MFCD30718265
MOL File:
40054-68-0.mol
Last updated:2024-03-26 14:13:49

Metizolam Properties

Melting point 153-154 °C
Boiling point 527.2±60.0 °C(Predicted)
Density 1.46±0.1 g/cm3(Predicted)
solubility DMF: 15mg/mL; DMSO: 15mg/mL; DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL
form A crystalline solid
pka 1.99±0.40(Predicted)
FDA UNII K1C6XI9LLX

Metizolam Chemical Properties,Uses,Production

Uses

Metizolam can be used as reactant/reagent in in preparation of thienylazole and thienotriazolodiazepine compounds as cholecystokinin antagonists. It can also be used in biological study of platelet-activating factor antagonist.

Metizolam synthesis

40054-40-8
40054-68-0
Synthesis of Metizolam from 5-(O-CHLOROPHENYL)-7-ETHYL-1,2-DIHYDRO-3H-THIENO[2,3-E][1,4]DIAZEPINE-2-THIONE

Metizolam Preparation Products And Raw materials

Raw materials

5-(O-CHLOROPHENYL)-7-ETHYL-1,2-DIHYDRO-3H-THIENO[2,3-E][1,4]DIAZEPINE-2-THIONE 5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one

Preparation Products

Metizolam 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, 4-(2-chlorophenyl)-2-ethyl- Metizolam (1.0 mg/mL in Methanol) Metizolam 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, 4-(2-chlorophenyl)-2-ethyl- Metizolam, Desmethyletizolam 40054-68-0