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(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE

CAS No.
86286-50-2
Chemical Name:
(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE
Synonyms
4,5-diphenyl-2-oxazolidinone;(4R,5S)-4,5-DIPHENYLOXAZOLIDIN-2-ONE;(4R,5S)-4,5-Diphenyl-2-oxazolidinone;2-Oxazolidinone, 4,5-diphenyl-, (4R,5S)-;(4R,5S)-cis-4,5-Diphenyloxazolidin-2-one;(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE;(4R,5S)-4,5-Diphenyl-2-oxazolidinone,99%e.e.;(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, ee: 98%;(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, 98%, ee: 98%
CBNumber:
CB1717996
Molecular Formula:
C15H13NO2
Molecular Weight:
239.27
MDL Number:
MFCD00674023
MOL File:
86286-50-2.mol
Last updated:2022-08-15 17:37:21

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Properties

Melting point 227-230 °C (lit.)
Boiling point 466.6±45.0 °C(Predicted)
Density 1.192±0.06 g/cm3(Predicted)
pka 11.56±0.60(Predicted)
optical activity [α]20/D 57±4°, c = 2 in methanol

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29029090

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 454540 (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone 98% 86286-50-2 1g $230 2023-01-07 Buy
American Custom Chemicals Corporation CHM0004668 (4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE 95.00% 86286-50-2 1G $744.02 2021-12-16 Buy
Chemenu CM190719 (4R,5S)-4,5-diphenyloxazolidin-2-one 95% 86286-50-2 5g $408 2021-12-16 Buy
Crysdot CD11042084 (4R,5S)-cis-4,5-Diphenyloxazolidin-2-one 95+% 86286-50-2 5g $432 2021-12-16 Buy
Ambeed A253448 (4R,5S)-cis-4,5-Diphenyloxazolidin-2-one 95+% 86286-50-2 5g $518 2021-12-16 Buy
Product number Packaging Price Buy
454540 1g $230 Buy
CHM0004668 1G $744.02 Buy
CM190719 5g $408 Buy
CD11042084 5g $432 Buy
A253448 5g $518 Buy

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Chemical Properties,Uses,Production

Chemical Properties

White powder or crystal

Uses

Versatile chiral auxiliary for asymmetric synthesis. For a recent review, see Aldrichimica Acta .

Preparation

To a stirred suspension of commercially available (10.0 g, 47 mmol) and triethylamine (14.4 mL, 0.10 mol) in dichloromethane (100 mL), diphosgene (3.0 mL, 25 mmol) was added dropwise at 0 °C and the mixture was stirred for 1 h at the same temperature. After concentration in vacuo, the residue was poured into water to precipitate crystals. The crystals were collected by filtration, successively washed with 10% HCl and H2O, and dried in vacuo at 50–60 °C for 3 h to afford 593a as colorless crystals (10.9 g, 97%).

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7191 65
Tianjin Derchemist Science & Technology Co., Ltd. 22-58627059 13920586291 zdcomcon@126.com China 3461 50
Shijiazhuang Lickon PharmaTech Co., Ltd. 031185291771 13832391721 yaofeng2005@163.com China 975 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 18112977050 cb6@aikonchem.com China 16684 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
Shanghai Chiral bio-compound co., Ltd. 021-5068 3667/17749785980/1029026415; 17749785980 1029026415@qq.com China 3013 58
(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE (4R,5S)-4,5-Diphenyl-2-oxazolidinone (4R,5S)-cis-4,5-Diphenyloxazolidin-2-one (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, ee: 98% (4R,5S)-4,5-Diphenyl-2-oxazolidinone,99%e.e. (4R,5S)-4,5-DIPHENYLOXAZOLIDIN-2-ONE (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, 98%, ee: 98% 4,5-diphenyl-2-oxazolidinone 2-Oxazolidinone, 4,5-diphenyl-, (4R,5S)- 86286-50-2 Oxazolidinone Derivatives Asymmetric Synthesis Chiral Auxiliaries Benzene derivatives Asymmetric Synthesis Chiral Auxiliaries Oxazolidinone Derivatives