OXITROPIUM BROMIDE
- CAS No.
- 30286-75-0
- Chemical Name:
- OXITROPIUM BROMIDE
- Synonyms
- Ba 253;ba253br;Oxivent;Ventilat;Tersigan;tersigat;oxitropium;ba-253-br-l;Oxitropiumbromid;oxitropiobromuro
- CBNumber:
- CB1727939
- Molecular Formula:
- C19H26BrNO4
- Molecular Weight:
- 412.32
- MDL Number:
- MFCD05664584
- MOL File:
- 30286-75-0.mol
Melting point | 203-204° (dec) |
---|---|
alpha | D21 -25° (c = 2.0 in water) |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | Very soluble in water, freely soluble in methanol, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. |
color | Off-White to Pale Yellow |
Stability | Hygroscopic |
FDA UNII | SF4NW7NH7C |
ATC code | R03BB02 |
OXITROPIUM BROMIDE price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | Y0000709 | Oxitropium bromide European Pharmacopoeia (EP) Reference Standard | 30286-75-0 | y0000709 | $220 | 2024-03-01 | Buy |
TRC | O847165 | Oxitropium bromide | 30286-75-0 | 10mg | $105 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003715 | OXITROPIUM BROMIDE 95.00% | 30286-75-0 | 5MG | $503.89 | 2021-12-16 | Buy |
OXITROPIUM BROMIDE Chemical Properties,Uses,Production
Description
Oxitropium bromide is an analog of the anticholinergics methscopolamine bromide and ipratropium bromide, useful in the treatment of bronchial asthma. Cited advantages include a long duration of action and lack of cardiovascular effects.
Chemical Properties
White or almost white, crystalline powder.
Originator
Boehringer Ingelheim (W. Germany)
Uses
Oxitropium Bromide is an anticholinergic agent.
Uses
Anticholinergic; treatment of reversible airways obstruction.
Manufacturing Process
14.5 g (0.05 mol) of (-)-norscopolamine and 5.4 g (0.05 mol) of ethyl bromide were dissolved in 300 cc of acetonitrile, 5.3 g (0.05 mol) of anhydrous sodium carbonate were suspended in the solution, and the suspension was heated at the boiling point for 10 hours. After a boiling time of 2.5 and 5 hours, respectively, the supply of ethyl bromide and sodium carbonate in the reaction mixture was replenished by adding each time 5.4 g (0.05 mol) of ethyl bromide and 5.3 g (0.05 mol) of anhydrous sodium carbonate. At the end of 10 hours of boiling, the inorganic sodium salts which had separated out were separated by vacuum filtration, the filter cake was washed with acetonitrile, and the acetonitrile was distilled out of the filtrate. The distillation residue was dissolved in ether, the solution was extracted with a small amount of water and then dried, and the ether was distilled off, yielding raw (-)-N-ethylnorscopolamine.
7.0 g (0.022 mol) of (-)-N-ethylnorscopolamine were dissolved in acetonitrile, 10.4 g (0.11 mol) of methyl bromide were added to the solution, and the mixture was allowed to stand at room temperature. The crystalline precipitate formed thereby was collected and recrystallized from acetonitrile.8.9 g (97.8% of theory) of white crystalline (-)-N-ethylnorscopolamine methobromide, melting point 203°C to 204°C (decomposition), were obtained.
brand name
Oxivent (Boehringer Ingelheim);TERSIGAT.
Therapeutic Function
Anticholinergic bronchodilator
Safety Profile
Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. An anticholinergic bronchodilator. When heated to decomposition it emits very toxic fumes of NOx and Brí.
OXITROPIUM BROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3632 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34571 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15395 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35426 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 17995 | 56 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
View Lastest Price from OXITROPIUM BROMIDE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-07-25 | OXITROPIUM BROMIDE
30286-75-0
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd |
-
- OXITROPIUM BROMIDE
30286-75-0
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd