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2-Amino-6-chloropurine Riboside

2-Amino-6-chloropurine Riboside Structure
2-Amino-6-chloropurine Riboside structure
CAS No.
2004-07-1
Chemical Name:
2-Amino-6-chloropurine Riboside
Synonyms
6-Cl-Gr;NSC 44586;2-Amino-6-chL;6-CHLOROADENOSINE;6-CHLOROGUANOSINE;6-Chloroguanosine2;oropurine riboside;Regadenoson Impurity 40;6-CHLOROGUANINE RIBOSIDE;2-NH2-6-Cl-purine-riboside
CBNumber:
CB1755136
Molecular Formula:
C10H12ClN5O4
Molecular Weight:
301.69
MDL Number:
MFCD00005735
MOL File:
2004-07-1.mol
MSDS File:
SDS
Last updated:2025-03-19 16:26:59
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2-Amino-6-chloropurine Riboside Properties

Melting point 165-167 °C (dec.)(lit.)
Boiling point 729.9±70.0 °C(Predicted)
Density 1.8359 (rough estimate)
refractive index -38 ° (C=0.1, H2O)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO, Methanol
pka 13.05±0.70(Predicted)
form Powder
color White to Off-white
InChIKey TXWHPSZYRUHEGT-ACJOCUEISA-N
CAS DataBase Reference 2004-07-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
Hazard Note  Irritant
HS Code  29349990
NFPA 704
0
1 0

2-Amino-6-chloropurine Riboside price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2054 2-Amino-6-chloropurine Riboside >95.0%(HPLC)(T) 2004-07-1 1g $50 2024-03-01 Buy
TCI Chemical A2054 2-Amino-6-chloropurine Riboside >95.0%(HPLC)(T) 2004-07-1 5g $196 2024-03-01 Buy
Alfa Aesar J64468 2-Amino-6-chloropurine riboside, 95% 2004-07-1 1g $99.65 2024-03-01 Buy
Alfa Aesar J64468 2-Amino-6-chloropurine riboside, 95% 2004-07-1 5g $191 2021-12-16 Buy
Usbiological A1376-58 2-Amino-6-chloropurine-9-b-D-riboside 2004-07-1 500mg $319 2021-12-16 Buy
Product number Packaging Price Buy
A2054 1g $50 Buy
A2054 5g $196 Buy
J64468 1g $99.65 Buy
J64468 5g $191 Buy
A1376-58 500mg $319 Buy

2-Amino-6-chloropurine Riboside Chemical Properties,Uses,Production

Chemical Properties

Colourless Crystalline Solid

Uses

2-Amino-6-chloropurine riboside (1) is a a novel class of inhibitors of endogenous protein degradation for the preparation of a number of important purine nucleoside derivatives. For example, 6-thioguanosine 2 and 6-selenoguanosine 3 were prepared from a reaction of 1 and the corresponding sodium thiosulfate or potassium selenosulfate.1) 18O-labeled guanosine 4 was incubated from 1 with adenosine deaminase in (18O)-water.2) 2-Amino-6-ethoxypurine riboside 5 and 2-amino-N6-amino-N6-methyladenosine 6 were prepared by treatment of 1 with nucleophiles, sodium ethoxide and methylhydrazine, respectively.3,4) 2-Amino-N6-substituted purine analogues, as typified by 6, were reported as anti-malarial active compounds.
2-Amino-6-chloropurine Riboside Reaction

References

[1] A. JANKOWSKI L. T D Wise. Sodium Thiosulfate and Potassium Selenosulfate as Reagents to Prepare Thio-and Selenopurine Nucleosides[J]. Nucleosides, Nucleotides & Nucleic Acids, 1989, 8 1: 339-348. DOI:10.1080/07328318908054179.
[2] SUNDEEP RAYAT. 5-Cyanoimino-4-oxomethylene-4,5-dihydroimidazole and 5-Cyanoamino-4-imidazolecarboxylic Acid Intermediates in Nitrosative Guanosine Deamination: Evidence from 18O-Labeling Experiments[J]. Journal of the American Chemical Society, 2004, 126 32: 9960-9969. DOI:10.1021/ja049835q.
[3] MORRIS J. ROBINS. Nucleic acid related compounds. 114. Synthesis of 2,6-(disubstituted)purine 2′,3′-dideoxynucleosides and selected cytotoxic, anti-hepatitis b, and adenosine deaminase substrate activities[J]. Journal of Heterocyclic Chemistry, 2009, 38 6: 1297-1306. DOI:10.1002/jhet.5570380609.
[4] KATHLEEN TOO . Anti-malarial activity of N6-modified purine analogues[J]. Bioorganic & Medicinal Chemistry, 2007, 15 16: Pages 5551-5562. DOI:10.1016/j.bmc.2007.05.038.
[5] ALICJA STACHELSKA-WIERZCHOWSKA. Tri-Cyclic Nucleobase Analogs and their Ribosides as Substrates of Purine-Nucleoside Phosphorylases. II Guanine and Isoguanine Derivatives.[J]. Molecules, 2019, 24 8. DOI:10.3390/molecules24081493.
[6] SHIH-HSI CHU Ming Y C Chyng Yann Shiue. Synthesis and cytotoxicity of 6-selenopurine arabinoside and related compounds[J]. Journal of pharmaceutical sciences, 1975, 64 8: 1343-1346. DOI:10.1002/jps.2600640818.

2-Amino-6-chloropurine Riboside Preparation Products And Raw materials

Raw materials

7-METHYLGUANINE 6-Chloroguanine

Preparation Products

2-Acetonyl-9-[3-deoxy-beta-d-ribouranosyl]hypoxanthine 2-AMino-6-chloropurine-9-(2'-O-Methyl)riboside

2-Amino-6-chloropurine Riboside Suppliers

Global( 330)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531157085 abby@chuanghaibio.com China 8808 58
Anhuyan (Hainan) Biotechnology Co., LTD 		+8618163349544 mollylucking@foxmail.com China 2764 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29730 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-+86-371-66670886 info@dakenam.com China 19805 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29858 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Yunbio Tech Co.,Ltd. 		+86-010-60605551 +86-18046518538 yunbiochem@126.com China 321 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8615060885618 sales@amoychem.com China 6383 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Anhuyan (Hainan) Biotechnology Co., LTD 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Yunbio Tech Co.,Ltd. 		58
Xiamen AmoyChem Co., Ltd 		58
Hubei xin bonus chemical co. LTD 		58
Alchem Pharmtech,Inc. 		58

View Lastest Price from 2-Amino-6-chloropurine Riboside manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-6-chloropurine-9-riboside pictures 2025-04-25 2-Amino-6-chloropurine-9-riboside
2004-07-1
 US $0.00-0.00 / Kg/Drum 1KG 98%min 500kg WUHAN FORTUNA CHEMICAL CO., LTD
2-Amino-6-chloropurine-9-riboside pictures 2025-04-23 2-Amino-6-chloropurine-9-riboside
2004-07-1
 US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Amino-6-chloropurine-9-riboside pictures 2025-04-22 2-Amino-6-chloropurine-9-riboside
2004-07-1
 US $0.00 / G/KG 1G/KG 99% 100000000KG Anhuyan (Hainan) Biotechnology Co., LTD

2-Amino-6-chloropurine Riboside Spectrum

2-Amino-6-chloropurine-9-riboside(2004-07-1)MS2-Amino-6-chloropurine-9-riboside(2004-07-1)1HNMR2-Amino-6-chloropurine-9-riboside(2004-07-1)13CNMR2-Amino-6-chloropurine-9-riboside(2004-07-1)IR12-Amino-6-chloropurine-9-riboside(2004-07-1)IR2

2004-07-1(2-Amino-6-chloropurine Riboside)Related Search:

PUROMYCIN AMINONUCLEOSIDE Adenosine Guanine Guanosine Guanosine 5'-monophosphate disodium salt
Glycine 6-Chloroguanine 6-Chloropurine Acyclovir Ribavirin
6-Chloropurine ribonucleoside 6-Methoxyguanine 3-Aminophenol 6-Aminocaproic acid 6-Thioguanine
NUCLEOSIDE PHOSPHORYLASE BACTERIAL 5'-Guanylic acid Tris(hydroxymethyl)aminomethane

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2-Amino-6-chloro-9-(beta-D-ribofuranosyl)-9H-purine 2-Amino-6-chloro-9H-purine-9-riboside, 6-Chloro-9-(beta-D-ribofuranosyl)-9H-purin-2-amine, (2R,3R,4S,5R)-2-(2-Amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 2-AMino-6-chloropurine riboside, Water ≤1.3% 6- chlorineguanine nucleotide 2-AMino-6-chloropurine riboside, water ≤4.5% 2-AMINO-6-CHLORO-9-(BETA-D-RIBOFURANOSYL)PURINE 2-AMINO-6-CHLOROPURINE-9-BETA-D-RIBOSIDE 2-AMINO-6-CHLOROPURINE-9-RIBOSIDE 2-AMINO-6-CHLOROPURINE RIBOSIDE 6-CHLOROADENOSINE 6-CHLOROGUANINE RIBOSIDE 6-CHLOROGUANOSINE 6-chloro-9-beta-D-ribofuranosyl-9H-purin-2-amine 2-Amino-6-chloro-9H-purine-9-riboside 2-Amino-6-chloropurine-9-b-D-riboside 2-Amino-6-chloro-9-(b-D-ribofuranosyl)purine 6-Chloroguanosine2 2-AMINO-6-CHLOROPURINE RIBOSIDE 97% (HPLC) 2-AMINO-6-CHLOROPURINE RIBOSIDE (6-CHLOROGUANOSINE) 9H-PURIN-2-AMINE, 6-CHLORO-9-.BETA.-D-RIBOFURANOSYL- 2-Amino-6-chloropurine-9--D-riboside 2-NH2-6-Cl-purine-riboside 6-Cl-Gr 9H-Purin-2-amine, 6-chloro-9-β-D-ribofuranosyl- 6-Chloroguanosine≥ 98% (HPLC) 6-Chloroguanine nucleoside 2-Amino-6-chloropurine-9-riboside,99% (-)-2-Amino-6-chloropurine riboside, 6-Chloroguanine riboside 1β-(2-Amino-6-chloro-9H-purine-9-yl)-1-deoxy-β-D-ribofuranose 2-Amino-6-chloro-9-β-D-ribofuranosyl-9H-purine 6-Chloro-9-(β-D-ribofuranosyl)-9H-purine-2-amine 6-Chloro-9-β-D-ribofuranosyl-9H-purin-2-amine 9-(β-D-Ribofuranosyl)-6-chloro-9H-purine-2-amine 2-Amino-6-chloropurine riboside ,98% 2-AMino-6-chloropurine Ribonucleoside NSC 44586 (2R,3R,4S,5R)-2-(2-aMino-6-chloro-9H-purin-9-yl)-5-(hydroxyMethyl)-tetrahydrofuran-3,4-diol 2-Amino-6-chloro-9-(β-D-ribofuranosyl)purine 2-Amino-6-chloropurine Riboside > 2-Amino-6-chL oropurine riboside 2-Amino-6-chloropurine-9-riboside, 6-Chloro-guanosine 2-Amino-6-chloropurine-9-riboside USP/EP/BP 2-Amino-6-chloropurine-9-β-D-riboside (2R,3R,4S,5R)-2-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 2-Amino-6-chloropurine riboside, 95%, water ≤4.5% 2-Amino-6-chloropurine riboside, 98%, Water ≤1.3% 2-Amino-6-chloropurine-9-ridoside 2-Amino-6-chloro purine-9-riboside, 2-Amino-6-chloro-9-(b-D-ribofurano syl)-9H-purine, endogenous protein degradation inhibitor -Amino-6-chloro purine-9-riboside (2R,3S,4R,5R)-2-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol Regadenoson Impurity 40 2004-07-1 2004-7-1 2004-07-01 2004-07-0 2004/7/1 BioChemical