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Imidapril

Imidapril Structure
Imidapril structure
CAS No.
89371-37-9
Chemical Name:
Imidapril
Synonyms
IMIDAPRIL;lmidaprfil;Imidapril HCl;Imidapril Hyd;Imidapril-d5 HCl;(S,S,S)-Imidapril;Imidapril USP/EP/BP;IMidapril (Tanatril);(s)-3-(n-((s)-1-ethoxycarbonyl-3-phenylpropyl)-l-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid;(4S)-3-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid
CBNumber:
CB1780943
Molecular Formula:
C20H27N3O6
Molecular Weight:
405.44
MDL Number:
MFCD00870777
MOL File:
89371-37-9.mol
Last updated:2024-10-28 23:16:16
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Imidapril Properties

Melting point 195-197°C
alpha D20 -71.7° (c = 0.5 in ethanol)
Boiling point 577.0±60.0 °C(Predicted)
Density 1.266±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
pka 2.44±0.20(Predicted)
form Solid
color White to off-white
CAS DataBase Reference 89371-37-9(CAS DataBase Reference)
FDA UNII BW7H1TJS22
ATC code C09AA16

Imidapril price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0006470 IMIDAPRIL 95.00% 89371-37-9 10MG $191.1 2021-12-16 Buy
American Custom Chemicals Corporation API0006470 IMIDAPRIL 95.00% 89371-37-9 100MG $1593.9 2021-12-16 Buy
Medical Isotopes, Inc. 11104 ImidaprilHCl 89371-37-9 50mg $1880 2021-12-16 Buy
AvaChem 1689B Imidapril 89371-37-9 10mg $59 2021-12-16 Buy
AvaChem 1689B Imidapril 89371-37-9 25mg $119 2021-12-16 Buy
Product number Packaging Price Buy
API0006470 10MG $191.1 Buy
API0006470 100MG $1593.9 Buy
11104 50mg $1880 Buy
1689B 10mg $59 Buy
1689B 25mg $119 Buy

Imidapril Chemical Properties,Uses,Production

Description

Imidapril is a new ACE inhibitor launched in Japan as a once-daily therapy for hypertension. Its active metabolite has more potent inhibitory effects on all tissue ACES from spontaneously hypertensive rats (SHRs) and Wistar Kyoto rats (WKYs) than many other ACE inhibitors including enalapril and captopril. It has a very long duration of action. In strokeprone spontaneously hypertensive rats (SHRSP), imidapril is effective in stroke prevention at a considerably lower dose than enalapril. This stroke preventive effect has been suggested to be primarily by an indirect mechanism related to the amelioration of kidney dysfunction.

Chemical Properties

White Solid

Originator

Tanabe (Japan)

Uses

Angiotensin converting enzyme (ACE) inhibitor. Antihypertensive

Definition

ChEBI: Imidapril is a member of the class of imidazolidines that is (4S)-1-methyl-2-oxoimidazolidine-4-carboxylic acid in which the hydrogen of the imidazolidine nitrogen has been substituted by (1S)-1-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}ethyl group. It is the prodrug for imidaprilat, an ACE inhibitor used for the treatment of chronic heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It is a dipeptide, a member of imidazolidines, a dicarboxylic acid monoester, a secondary amino compound, an ethyl ester and a N-acylurea.

brand name

Tanatril; Novarok

Imidapril Preparation Products And Raw materials

Raw materials

N-Hydroxysuccinimide Potassium tert-butoxide Ethyl butyrate Benzyl ester 4-Phenylbutyric acid
Propionyl chloride Midazopril hydrochloride 1-Methylpyrazole-4-ethoxycarbonyl-5-ethoxycarbonylsulfonamide Bromobenzene Imidazolidine
Aniline D-Alanine Tert-butyl ester Iodomethane (2S)-1-(3-Acetylthio-2-methyl-1-oxopropyl)-L-proline

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Preparation Products

Imidapril Suppliers

Global( 115)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29792 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29871 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49476 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 7724 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15352 58
Wuhan Fortuna Chemical Co., Ltd 		+86-027-59207850 info@fortunachem.com China 5972 58
Sinoway Industrial co., ltd. 		0592-5800732; +8613806035118 xie@china-sinoway.com China 988 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
LUYUNJIA CHEMISTRY XIAMEN LIMITED 		+86-592-5360779 +86-13055435203 China 5988 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Shaanxi Dideu Medichem Co. Ltd 		58
AFINE CHEMICALS LIMITED 		58
Wuhan Fortuna Chemical Co., Ltd 		58
Sinoway Industrial co., ltd. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
LUYUNJIA CHEMISTRY XIAMEN LIMITED 		58

View Lastest Price from Imidapril manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Imidapril Hydrochloride pictures 2025-02-12 Imidapril Hydrochloride
89371-37-9
 US $0.00-0.00 / Kg/Drum 1KG 99%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
Imidapril pictures 2024-10-28 Imidapril
89371-37-9
 US $3520.00-2785.00 / mg 10g TargetMol Chemicals Inc.
Imidapril pictures 2020-05-10 Imidapril
89371-37-9
 US $0.00-0.00 / Kg 1KG 99.0% 500 MT Shaanxi Dideu Medichem Co. Ltd
  • Imidapril pictures
  • Imidapril
    89371-37-9
  • US $3520.00-2785.00 / mg
  • TargetMol Chemicals Inc.
  • Imidapril pictures
  • Imidapril
    89371-37-9
  • US $0.00-0.00 / Kg
  • 99.0%
  • Shaanxi Dideu Medichem Co. Ltd

89371-37-9(Imidapril)Related Search:

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1-(2,6-Dimethylphenoxy)-2-propanamine Methyl Methyl bromide Carbonyl iron powder NICKEL CARBONYL
1-(2-AMINOETHYL)-2-IMIDAZOLIDONE Imidapril Diacid N-ISOPROPYL-AMINO-ACETIC ACID ETHYL ESTER HCL

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(s)-3-(n-((s)-1-ethoxycarbonyl-3-phenylpropyl)-l-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid IMIDAPRIL (4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic Aci 4-Imidazolidinecarboxylic acid, 3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, (4S)- 4-Imidazolidinecarboxylic acid, 3-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, [4S-[3[R*(R*)],4R*]]- (4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic Acid Hydrochloride (4S)-3-[(2S)-2-[N-[(1S)-1-(Ethyoxycarbonyl)-3-phenylpropyl]amino]propionyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid lmidaprfil (4S)-3-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino]propionyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid (4S)-3-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid (S,S,S)-Imidapril Imidapril HCl IMidapril (Tanatril) Imidapril-d5 HCl Imidapril USP/EP/BP Imidapril Hyd 89371-37-9 9371-37-9 C20H27N3O6 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals