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ChemicalBook >> CAS DataBase List >>Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Structure
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- structure
CAS No.
2305936-70-1
Chemical Name:
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Synonyms
OUN 36701;Poma-C?-COOH;Thalidomide-4-NH-C8-COOH;Pomalidomide 4'-alkylC8-acid;9-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]amino]nonanoic Acid;9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)nonanoic acid;9-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}nonanoic acid;Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
CBNumber:
CB18344509
Molecular Formula:
C22H27N3O6
Molecular Weight:
429.47
MDL Number:
MOL File:
2305936-70-1.mol
Last updated:2024-10-28 16:48:35
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Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Properties

Boiling point 718.9±60.0 °C(Predicted)
Density 1.351±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
pka 4.78±0.10(Predicted)

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Chemical Properties,Uses,Production

Description

Pomalidomide C8-acid, also known as Pomalidomide 4'-alkylC8-acid and OUN36701, is a Pomalidomide-based cereblon ligand with a linker, which is a useful precursor for synthesis of PROTAC degraders. Targeted protein degradation (TPD) is an emerging therapeutic modality with the potential to tackle disease-causing proteins that have historically been highly challenging to target with conventional small molecules. PROTAC degraders are usually heterobifunctional small molecules consisting of two ligands joined by a linker: one ligand recruits and binds a protein of interest (POI) while the other recruits and binds an E3 ubiquitin ligase. Simultaneous binding of the POI and ligase by the PROTAC induces ubiquitylation of the POI and its subsequent degradation by the ubiquitin–proteasome system (UPS), after which the PROTAC is recycled to target another copy of the POI.ubiquitylation of the POI and its subsequent degradation by the ubiquitin–proteasome system (UPS), after which the PROTAC is recycled to target another copy of the POI.

storage

Store at -20°C

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Suppliers

Global( 20)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32118 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7189 65
Chengdu Novel Biomedical Co., Ltd. 028-85255396 18302801538 cdnovell@163.com China 2310 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1388 58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD 025-86755008 17751752005 hszhang@bestfluorodrug.com China 2358 58
Zhengzhou convergence chemical co., LTD 0371-0371-55153829 18003835034 2853979819@qq.com China 9718 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2881924765@qq.com China 8139 58
Wuhan Augda Biotechnology Co., Ltd 15071299552 262933239@qq.com China 6883 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62163 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Daicel Chiral Technologies (China)CO.,LTD 65
Chengdu Novel Biomedical Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD 58
Zhengzhou convergence chemical co., LTD 58
Hubei Kele Fine Chemical Co., Ltd 58
Wuhan Augda Biotechnology Co., Ltd 58
Bide Pharmatech Ltd. 58

View Lastest Price from Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide 4'-alkylC8-acid pictures 2024-10-28 Pomalidomide 4'-alkylC8-acid
2305936-70-1
 US $523.00 / mg 10g TargetMol Chemicals Inc.

2305936-70-1(Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-)Related Search:

4-((2-azidoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione INDEX NAME NOT YET ASSIGNED E3 ligase Ligand-Linker Conjugates 49 Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide 6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid
Pomalidomide-C6-PEG3-butyl iodide POMALIDOMIDE-C9-CO2H Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl E3 ligase Ligand-Linker Conjugates 55
1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Pomalidomide-6-2-2-6-N3 Pomalidomide-amido-C1-Br Pomalidomide-C6-NH2?hydrochloride Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

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Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- OUN 36701 9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)nonanoic acid Thalidomide-4-NH-C8-COOH 9-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]amino]nonanoic Acid Poma-C?-COOH Pomalidomide 4'-alkylC8-acid 9-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}nonanoic acid 2305936-70-1