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Pomalidomide-C6-PEG3-butyl iodide

Pomalidomide-C6-PEG3-butyl iodide Structure
Pomalidomide-C6-PEG3-butyl iodide structure
CAS No.
1835705-70-8
Chemical Name:
Pomalidomide-C6-PEG3-butyl iodide
Synonyms
Poma-6-2-2-6-I;Pomalidomide-6-2-2-6-I;Pomalidomide-C6-PEG3-butyl iodide;N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]-6-[2-[2-(6-iodohexoxy)ethoxy]ethoxy]hexanamide;Hexanamide, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-6-[2-[2-[(6-iodohexyl)oxy]ethoxy]ethoxy]-;N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-6-(2-(2-((6-iodohexyl)oxy)ethoxy)ethoxy)hexanamide, Crosslinker?E3 Ligase ligand conjugate, Pomalidomide-6-2-2-6-I, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
CBNumber:
CB75430559
Molecular Formula:
C29H40IN3O8
Molecular Weight:
685.55
MDL Number:
MFCD32173805
MOL File:
1835705-70-8.mol
MSDS File:
SDS
Last updated:2024-04-01 13:48:23
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Pomalidomide-C6-PEG3-butyl iodide Properties

Boiling point 813.9±65.0 °C(Predicted)
Density 1.446±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 10.69±0.40(Predicted)

Pomalidomide-C6-PEG3-butyl iodide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 904708 Pomalidomide-C6-PEG3-butyl iodide ≥95% 1835705-70-8 50MG $473 2023-06-20 Buy
Iris Biotech GmbH PTC1700 Pomalidomid-C6-PEG3-butyl-I 1835705-70-8 50mg $567 2021-12-16 Buy
Product number Packaging Price Buy
904708 50MG $473 Buy
PTC1700 50mg $567 Buy

Pomalidomide-C6-PEG3-butyl iodide Chemical Properties,Uses,Production

Uses

Protein degrader builiding block Pomalidomide-C6-PEG3-butyl iodide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant iodoalkane for reactivity with a nucleophilic group on a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant iodo group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

Pomalidomide-C6-PEG3-butyl iodide Preparation Products And Raw materials

Raw materials

Preparation Products

Pomalidomide-C6-PEG3-butyl iodide Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9854 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4824 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1365 58
Shaanxi borno biotechnology co., LTD +86-13759708231 asherw9@hotmail.com China 2351 58
Zhengzhou convergence chemical co., LTD 0371-0371-55153829 18003835034 2853979819@qq.com China 8986 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18488 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 40873 58
Supplier Advantage
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Xian confluore Biological Technology Co., Ltd. 		58
Sigma-Aldrich 80
Shanghai Chaolan Chemical Technology Center 58
Xi'an Confluore Biological Technology Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Shaanxi borno biotechnology co., LTD 58
Zhengzhou convergence chemical co., LTD 58
Changzhou Bojia Biomedical Technology Co., Ltd. 58
Jilin Chinese Academy of Sciences-yanshen Technology 58

View Lastest Price from Pomalidomide-C6-PEG3-butyl iodide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-6-2-2-6-I pictures 2024-04-02 Pomalidomide-6-2-2-6-I
1835705-70-8
 US $0.00 / mg 100mg >95.00% 100mg Xian confluore Biological Technology Co., Ltd.

1835705-70-8(Pomalidomide-C6-PEG3-butyl iodide)Related Search:

E3 ligase Ligand-Linker Conjugates 49 6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl E3 ligase Ligand-Linker Conjugates 55
1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Pomalidomide-6-2-2-6-N3 Pomalidomide-amido-C1-Br Pomalidomide-C6-NH2?hydrochloride Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide POMALIDOMIDE-C9-CO2H

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Pomalidomide-C6-PEG3-butyl iodide Pomalidomide-6-2-2-6-I N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]-6-[2-[2-(6-iodohexoxy)ethoxy]ethoxy]hexanamide Hexanamide, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-6-[2-[2-[(6-iodohexyl)oxy]ethoxy]ethoxy]- N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-6-(2-(2-((6-iodohexyl)oxy)ethoxy)ethoxy)hexanamide, Crosslinker?E3 Ligase ligand conjugate, Pomalidomide-6-2-2-6-I, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader Poma-6-2-2-6-I 1835705-70-8