alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride
- CAS No.
- 326-43-2
- Chemical Name:
- alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride
- Synonyms
- Vazalmin;Firmalgil;Phenyramidol HCl;FENYRAMIDOLHYDROCHLORIDE;1-Phenyl-2-(pyridin-2-ylamino)ethanol hydrochloride;alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride;Benzenemethanol, a-[(2-pyridinylamino)methyl]-,hydrochloride (1:1)
- CBNumber:
- CB1906929
- Molecular Formula:
- C13H15ClN2O
- Molecular Weight:
- 250.724
- MDL Number:
- MFCD00242757
- MOL File:
- 326-43-2.mol
- MSDS File:
- SDS
Melting point | 140-142° |
---|---|
FDA UNII | M574V6XQH7 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Toxicity | LD50 oral in mouse: 2425mg/kg |
alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Chemical Properties,Uses,Production
Originator
Analexin, Mallinckrodt Inc., US ,1960
Uses
Analgesic; relaxant (skeletal muscle).
Manufacturing Process
A mixture containing 188 g (0.20 mol) of 2-arninopyridine, 0.55 g of lithium amide and 75 cc of anhydrous toluene was refluxed for 1.5 hours. Styrene oxide (12.0 g = 0.10 mol) was then added to the reaction mixture with stirring over a period of ten minutes. The reaction mixture was stirred and refluxed for an additional 3.5 hours. A crystalline precipitate was formed during the reaction which was removed by filtration, MP 170°C to 171°C. 1.5 g. The filtrate was concentrated to dryness and a dark residue remained which was crystallized from anhydrous ether; yield 6.0 g. Upon recrystallization of the crude solid from 30 cc of isopropyl alcohol, 2.0 g of a light yellow solid was isolated; MP 170° to 171°C.
Therapeutic Function
Analgesic, Muscle relaxant
alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Preparation Products And Raw materials
alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15395 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
Wuhan Yuxiang Medical Technology Co., Ltd. | 13971275651 | sales@whyxpharma.com | China | 4352 | 58 |
Shaanxi kelkai Pharmaceutical Technology Co., Ltd | 029-029-2148545164 17392779578 | 2148545164@qq.com | China | 6578 | 58 |
Pushan Industry (Shaanxi) Co., Ltd | 029-81310890 18165209495 | 2929288192@qq.com | China | 10003 | 58 |