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PF-06807656

PF-06807656 structure

CAS No.: 2213468-04-1

Chemical Name:: PF-06807656

Synonyms: PF-06807656;Benzamide, 3-[[(4-chlorophenyl)amino]sulfonyl]-4-methoxy-N-[1-(2-methyl-2H-1,2,3-triazol-4-yl)ethyl]-

CBNumber:: CB19631244

Molecular Formula:: C19H20ClN5O4S

Molecular Weight:: 449.91

MDL Number:

MOL File:: 2213468-04-1.mol

Last updated:2025-01-27 09:38:02

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PF-06807656 Properties

Density	1.43±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 2mg/mL, clear
pka	7.35±0.10(Predicted)
form	powder
color	white to beige
UNSPSC Code	51111800
NACRES	NA.77

PF-06807656 Chemical Properties,Uses,Production

Biological Activity

PF-06807656 is a 3-sulfamoylbenzamide-based renal outer medullary potassium channel (ROMK, CCNJ1, Kir1.1) inhibitor (IC50 = 61 nM by whole cell patch clamp) th at is insensitive to K80M or N171D pore mutation and exhibits high selectivity for human over r at species (IC50 against thallium sulfate/TlSO4-stimulated influx = 391 nM vs. >30 μM using human or r at ROMK1-expressing HEK293 cells; 82% vs. 0% inhibition by patch clamp using human or r at ROMK2-expressing HEK293 cells).

PF-06807656 Preparation Products And Raw materials

Raw materials

Preparation Products

PF-06807656 Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Biorbyt Ltd.	--	info@biorbyt.com	CHINA	6579	58

Supplier	Advantage
Biorbyt Ltd.	58

PF-06807656 Benzamide, 3-[[(4-chlorophenyl)amino]sulfonyl]-4-methoxy-N-[1-(2-methyl-2H-1,2,3-triazol-4-yl)ethyl]- 2213468-04-1