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HYDROXYFASUDIL MONOHYDROCHLORIDE

HYDROXYFASUDIL MONOHYDROCHLORIDE structure

CAS No.: 155558-32-0

Chemical Name:: HYDROXYFASUDIL MONOHYDROCHLORIDE

Synonyms: Fasudil Hydroxy;Hydroxyfasudil HCl;Fasudil Impurity 7 HCl;Hydroxyfasudil (HA-1100);Hydroxyfasudil HCl (HA1100);Hydroxyfasudil Hydrochloride;Hydroxyfasudil (HA-1100) HCl;HYDROXYFASUDIL MONOHYDROCHLORIDE;Hydroxyfasudil hydrochloride hydrate;HA 1100 hydrochloride (Hydroxyfasudil)

CBNumber:: CB1973040

Molecular Formula:: C14H18ClN3O3S

Molecular Weight:: 343.82902

MDL Number:: MFCD06411567

MOL File:: 155558-32-0.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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HYDROXYFASUDIL MONOHYDROCHLORIDE Properties

Melting point	>250 (dec.)
storage temp.	Inert atmosphere,2-8°C
solubility	H2O: >5mg/mL
form	solid
color	white
Water Solubility	Soluble in water (20mM)
InChIKey	XWWFOUVDVJGNNG-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P501

Hazard Codes

Risk Statements

WGK Germany

NFPA 704

	0
2		0

HYDROXYFASUDIL MONOHYDROCHLORIDE price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H4413	Hydroxyfasudil hydrochloride hydrate ≥98% (HPLC), solid	155558-32-0	5mg	$286	2024-03-01	Buy
Sigma-Aldrich	390602	Hydroxyfasudil	155558-32-0	2mg	$159	2024-03-01	Buy
Cayman Chemical	14413	HA-1100 (hydrochloride) ≥98%	155558-32-0	1mg	$32	2024-03-01	Buy
Cayman Chemical	14413	HA-1100 (hydrochloride) ≥98%	155558-32-0	5mg	$116	2024-03-01	Buy
Sigma-Aldrich	H4413	Hydroxyfasudil hydrochloride hydrate ≥98% (HPLC), solid	155558-32-0	25mg	$1080	2024-03-01	Buy

Product number	Packaging	Price	Buy
H4413	5mg	$286	Buy
390602	2mg	$159	Buy
14413	1mg	$32	Buy
14413	5mg	$116	Buy
H4413	25mg	$1080	Buy

HYDROXYFASUDIL MONOHYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.

General Description

A cell-permeable, hydroxylated metabolite of HA 1077 (Fasudil; Cat. No. 371970) that displays anti-anginal properties. Acts as an ATP-competitive and a reversible inhibitor of Rho-kinase (IC₅₀ = 0.9 and 1.8 μM using a peptide and MLC as substrate, respectively) with ~100-fold greater selectivity over MLCK, MRCKβ, and PKC. Reported to inhibit the Rho kinase-mediated contraction both in vitro and in vivo.

Biochem/physiol Actions

Cell permeable: yes

storage

-20°C

HYDROXYFASUDIL MONOHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

HYDROXYFASUDIL MONOHYDROCHLORIDE Suppliers

Global( 101)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9639	58
Alfa Chemistry		Info@alfa-chemistry.com	United States	24072	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11922	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58

Supplier	Advantage
Standardpharm Co. Ltd.	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Finetech Industry Limited	58
Alfa Chemistry	58
InvivoChem	58
TargetMol Chemicals Inc.	58
China National Standard Pharmaceutical Corporation Limited	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
LEAPCHEM CO., LTD.	58

View Lastest Price from HYDROXYFASUDIL MONOHYDROCHLORIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	Hydroxyfasudil Hydrochloride 155558-32-0	US $55.00-127.00 / mg		99.82%	10g	TargetMol Chemicals Inc.

Hydroxyfasudil Hydrochloride
155558-32-0
US $55.00-127.00 / mg
99.82%
TargetMol Chemicals Inc.

HYDROXYFASUDIL MONOHYDROCHLORIDE Spectrum

HYDROXYFASUDIL MONOHYDROCHLORIDE(155558-32-0)¹HNMR

155558-32-0(HYDROXYFASUDIL MONOHYDROCHLORIDE)Related Search:

5-Quinolinesulfonic acid, 2-methyl- Fasudil Pyridine N-Oxide TFA Salt 1,4-ditosyl-1,4-diazepane Fasudil diMer Fasudil Impurity 6

Fasudil Impurity 13 Fasudil N-hydroxy iMpurity 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol quinoline-5-sulphonic acid Fasudil Impurity

8-Methylquinoline 2-METHYLQUINOLINE-6-SULFONIC ACID Quinoline Fasudil IMpurity 3 1-(p-Toluenesulfonyl)hoMopiperazine, 95%

Isoquinoline Fasudil Impurity 8 N-(3-HYDROXYPROPYL)ETHYLENEDIAMINE

1of4

5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone Hydroxyfasudil Hydrochloride 1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine monohydrochloride HYDROXYFASUDIL MONOHYDROCHLORIDE Hydroxyfasudil hydrochloride hydrate,1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate Hydroxyfasudil hydrochloride hydrate Hydroxyfasudil (HA-1100) HA-1100 HYDROCHLORIDE;HA 1100 HYDROCHLORIDE;HA1100 HYDROCHLORIDE 5-(1,4-diazepan-1-ylsulfonyl)-2h-isoquinolin-1-one Hydroxyfasudil hydrochloride (HA-1100 hydrochloride) Hydroxyfasudil - CAS 155558-32-0 - Calbiochem Hydroxyfasudil HCl Hydroxyfasudil (HA-1100) HCl 1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1) Fasudil Impurity 7 HCl Fasudil Hydroxy 5-((1,4-diazepan-1-yl)sulfonyl)isoquinolin-1-ol hydrochloride 5-[(1,4-Diazepan-1-yl)sulfonyl]isoquinolin-1(2H)-one Hydrochloride Hydroxyfasudil HCl (HA1100) 5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one,hydrochloride HA-1100,ROCK,Hydroxyfasudil Hydrochloride,Hydroxyfasudil,Rho-associated kinase,HA 1100,inhibit,HA1100,Rho-kinase,Rho-associated protein kinase,ROK,Inhibitor Hydroxyfasudil hydrochloride hydrate Hydroxyfasudil hydrochloride HA 1100 hydrochloride (Hydroxyfasudil) HA 1100 hydrochloride (Hydroxyfasudil), Rho-kinase inhibitor 155558-32-0 C14H17N3O3SHCl Various Metabolites and Impurities Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals