(R)-(-)-alpha-Methoxyphenylacetic acid
- CAS No.
- 3966-32-3
- Chemical Name:
- (R)-(-)-alpha-Methoxyphenylacetic acid
- Synonyms
- (R)-2-Methoxy-2-phenylacetic acid;(R)-(-)-α-Methoxyphenylacetic Acid;(R)-(-)-αBenzeneacetic acid, .a;O-METHYL-D-MANDELIC ACID;O-Methyl-(R)-mandelicacid;Acetic acid, methoxyphenyl;(-)-Methoxyphenylacetic acid;(1)-(Methoxy)phenylacetic acid;(methyloxy)(phenyl)acetic acid
- CBNumber:
- CB2105770
- Molecular Formula:
- C9H10O3
- Molecular Weight:
- 166.17
- MDL Number:
- MFCD00004250
- MOL File:
- 3966-32-3.mol
- MSDS File:
- SDS
Melting point | 66-68 °C(lit.) |
---|---|
Boiling point | 164-166°C 18mm |
alpha | -160.4 º (C=1, MEOH) |
Density | 1.1708 (rough estimate) |
refractive index | -147 ° (C=0.5, EtOH) |
Flash point | 164-166°C/18mm |
storage temp. | 2-8°C |
solubility | Chloroform, Ethanol, Methanol |
form | Fine Crystalline Powder or Needles |
pka | 3.10±0.10(Predicted) |
color | White |
optical activity | [α]20/D -150±3°, c = 0.5% in ethanol |
BRN | 3589257 |
CAS DataBase Reference | 3966-32-3(CAS DataBase Reference) |
FDA UNII | WA8N5X9TFK |
NIST Chemistry Reference | (R)-(-)-«alpha»-methoxyphenylacetic acid(3966-32-3) |
UNSPSC Code | 12352112 |
NACRES | NA.22 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 29189900 | |||||||||
NFPA 704 |
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(R)-(-)-alpha-Methoxyphenylacetic acid price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 248967 | (R)-(?)-α-Methoxyphenylacetic acid 99% | 3966-32-3 | 1g | $208 | 2024-03-01 | Buy |
Sigma-Aldrich | 65209 | (R)-(?)-α-Methoxyphenylacetic acid for chiral derivatization, ≥99.0% | 3966-32-3 | 1g | $310 | 2022-05-15 | Buy |
TCI Chemical | M0830 | (R)-(-)-alpha-Methoxyphenylacetic Acid >98.0%(GC)(T) | 3966-32-3 | 1g | $39 | 2024-03-01 | Buy |
TCI Chemical | M0830 | (R)-(-)-alpha-Methoxyphenylacetic Acid >98.0%(GC)(T) | 3966-32-3 | 5g | $123 | 2024-03-01 | Buy |
Alfa Aesar | L08719 | (R)-(-)-alpha-Methoxyphenylacetic acid, 99% | 3966-32-3 | 250mg | $37.65 | 2024-03-01 | Buy |
(R)-(-)-alpha-Methoxyphenylacetic acid Chemical Properties,Uses,Production
Chemical Properties
white fine crystalline powder or needles
Uses
(R)-(-)-α-Methoxyphenylacetic Acid is a useful synthetic intermediate. It is used as a reactant in the synthesis of dopamine receptor agonists. It can also be used to prepare hydroxytriamides as potent γ-secretase inhibitors.
General Description
(R)-(?)-α-Methoxyphenylacetic acid is a chiral derivatizating agent, which is employed for derivatizing enantiomers into diastereoisomers.
Purification Methods
Purify the acids by recrystallising from *C6H6/pet ether (b 80-100o). [Neilson & Peters J Chem Soc 1519 1962, Weizmann et al. J Am Chem Soc 70 1153 1948, Pirie & Smith J Chem Soc 338 1932, NMR: Dale & Mosher J Am Chem Soc 9 5 512 1973, for resolution: Roy & Deslongchamps Can J Chem 63 651 1985, Trost et al. J Am Chem Soc 1 0 8 4974 1986.] The racemic mixture has m 72o, b 121-122o/0.4mm, 165o/18mm (from pet ether) [Braun et al. Chem Ber 6 3 2847 1930]. [Beilstein 10 IV 566.]
(R)-(-)-alpha-Methoxyphenylacetic acid Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18142 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19852 | 58 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29866 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 18645 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from (R)-(-)-alpha-Methoxyphenylacetic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-10-25 | (R)-(-)-alpha-Methoxyphenylacetic acid
3966-32-3
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
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2022-09-28 | (R)-(-)-alpha-Methoxyphenylacetic acid
3966-32-3
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
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2019-07-06 | (R)-(-)-alpha-Methoxyphenylacetic acid
3966-32-3
|
US $1.00 / kg | 1kg | 95%-99% | as request | Career Henan Chemical Co |
-
- (R)-(-)-alpha-Methoxyphenylacetic acid
3966-32-3
- US $0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- (R)-(-)-alpha-Methoxyphenylacetic acid
3966-32-3
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- (R)-(-)-alpha-Methoxyphenylacetic acid
3966-32-3
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co
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