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ChemicalBook >> CAS DataBase List >>2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Structure
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- structure
CAS No.
2408882-54-0
Chemical Name:
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-
Synonyms
BCL6-IN-6;BCL6 IN 6,BCL6IN6;2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-
CBNumber:
CB211207269
Molecular Formula:
C27H31FN6O2S
Molecular Weight:
522.64
MDL Number:
MOL File:
2408882-54-0.mol
Last updated:2024-10-30 20:13:01
Request For Quotation

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Properties

Density 1.301±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka 11.58±0.70(Predicted)
color Light yellow to yellow

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Chemical Properties,Uses,Production

Biological Activity

BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL)[1].

References

[1]. Guo W, et al. Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth. J Med Chem. 2020;63(2):676-695.

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32063 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 6954 58
Absin Bioscience Inc. 021-38015121 15000105423 wulan@absin.cn China 24731 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19711 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12005 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Chaolan Chemical Technology Center 58
Absin Bioscience Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

View Lastest Price from 2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BCL6-IN-6 pictures 2024-10-30 BCL6-IN-6
2408882-54-0
 US $69.00-173.00 / mg 97.61% 10g TargetMol Chemicals Inc.
  • BCL6-IN-6 pictures
  • BCL6-IN-6
    2408882-54-0
  • US $69.00-173.00 / mg
  • 97.61%
  • TargetMol Chemicals Inc.

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Spectrum

2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-(2408882-54-0)1HNMR
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- BCL6-IN-6 BCL6 IN 6,BCL6IN6 2408882-54-0 C27H31FN6O2S