ChemicalBook >> CAS DataBase List >>TTBK1-IN-2
TTBK1-IN-2
- CAS No.
- 2765453-51-6
- Chemical Name:
- TTBK1-IN-2
- Synonyms
- TTBK1-IN-2;TTBK1-IN-2, 10 mM in DMSO;N-(4-(4-Chlorophenoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-[4-(4-chlorophenoxy)phenyl]-
- CBNumber:
- CB211410968
- Molecular Formula:
- C18H13ClN4O
- Molecular Weight:
- 336.77
- MDL Number:
- MOL File:
- 2765453-51-6.mol
Last updated:2024-11-13 11:39:26
TTBK1-IN-2 Chemical Properties,Uses,Production
Biological Activity
TTBK1-IN-2 (compound 29) is a potent Tau-Tubulin kinase (TTBK1) inhibitor with IC50s of 0.24 and 4.22 μM, respectively. TTBK1-IN-2 reveals good brain penetration in vivo and is able to reduce TDP-43 phosphorylation not only in cell cultures but also in the spinal cord of transgenic TDP-43 mice[1].
References
[1]. Nozal V, et al. TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy. J Med Chem. 2022;65(2):1585-1607.
TTBK1-IN-2 Preparation Products And Raw materials
Raw materials
Preparation Products
TTBK1-IN-2 Suppliers
Global( 14)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 5960 | 55 |
Zhengzhou convergence chemical co., LTD | 0371-0371-55153829 18003835034 | 2853979819@qq.com | China | 9858 | 58 |
Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62075 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24644 | 58 |
Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 6830 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9266 | 58 |
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd | 13915962545 | 2881759498@qq.com | China | 8827 | 58 |
400-821-026 | sangon@qq.com | China | 47239 | 58 |
View Lastest Price from TTBK1-IN-2 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-11-12 | TTBK1-IN-2
2765453-51-6
|
US $74.00-252.00 / mg | 99.83% | 10g | TargetMol Chemicals Inc. |
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- TTBK1-IN-2
2765453-51-6
- US $74.00-252.00 / mg
- 99.83%
- TargetMol Chemicals Inc.
TTBK1-IN-2
7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-[4-(4-chlorophenoxy)phenyl]-
N-(4-(4-Chlorophenoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
TTBK1-IN-2, 10 mM in DMSO
2765453-51-6